Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Henryk Chmara"'
Publikováno v:
European Journal of Medicinal Chemistry. 29:61-67
A series of peptides with N 3 -( S )-bromosuccinamoyl-( S )-2,3-diaminopropanoic acid, a novel selective inhibitor of glucosamine-6-phosphate synthase were synthesized and evaluated in vitro for antimicrobial activity against selected bacterial and f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fc419aea19a8f7551b19a25b70af5d9
https://doi.org/10.1016/0223-5234(94)90127-9
https://doi.org/10.1016/0223-5234(94)90127-9
Publikováno v:
The Journal of Antibiotics. 47:715-723
Peptide analogues of Sch 37137 the antifungal antibiotic have been synthesized and evaluated in vitro against Candida sp. Di- and tripeptides containing methionine, leucine, norvaline, lysine, glutamic acid and N3-(trans-epoxysuccinamoyl)-L-2,3-diami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1333f9bbdf5f9c47f6d8735522a4a66a
https://doi.org/10.7164/antibiotics.47.715
https://doi.org/10.7164/antibiotics.47.715
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1115:225-229
N3-Haloacetyl derivatives of L-2,3-diaminopropanoic acid, novel glutamine analogs, were shown to be strong inhibitors of glucosamine-6-phosphate synthase from bacteria and Candida albicans. The inhibition was competitive with respect to glutamine and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7578db2dc11663a9e3b395f9449849c2
https://doi.org/10.1016/0304-4165(92)90058-3
https://doi.org/10.1016/0304-4165(92)90058-3
Several dipeptides, containing the N 3-(4-methoxyfumaroyl)-L-2,3-diaminopropanoic acid (FMDP) moiety linked to protein and non-protein amino acids, exhibited a strong growth-inhibitory and bactericidal effect against Bacillus subtilis. FMDP-dipeptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0b95656706832080f9b6a3b75af423c
http://hdl.handle.net/11581/317209
http://hdl.handle.net/11581/317209
Publikováno v:
Journal of general microbiology. 137(4)
The glycopeptide antibiotic teicoplanin belongs to the same group as vancomycin and ristocetin and is a valuable tool for studying the autolytic system of sensitive Gram-positive bacteria. Teicoplanin, at a concentration of 1 microgram ml-1, caused r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd569add430972f099568aaa523e1dd
https://pubmed.ncbi.nlm.nih.gov/1830328
https://pubmed.ncbi.nlm.nih.gov/1830328
Publikováno v:
Journal of medicinal chemistry. 33(10)
Six peptide conjugates consisting of either norvaline, methionine, or lysine and N3-(iodoacetyl)-L-2,3-diaminopropanoic acid--a strong, irreversible inactivator of bacterial and fungal glucosamine-6-phosphate synthase--were synthesized and their anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7739bf559cd062b2381ebafc9dc66a48
https://pubmed.ncbi.nlm.nih.gov/2120441
https://pubmed.ncbi.nlm.nih.gov/2120441
Publikováno v:
The Journal of Antibiotics. 37:1038-1043
Glucosamine-6-phosphate synthetase from Escherichia coli K-12 is progressively inactivated L-beta-(2,3-epoxycyclohexyl-4-on)alanine (anticapsin). With increasing concentrations of anticapsin the reaction exhibits rate saturation: the minimum inactiva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55cb7ced9cc201f69e036e26b38ce823
https://doi.org/10.7164/antibiotics.37.1038
https://doi.org/10.7164/antibiotics.37.1038
Publikováno v:
The Journal of Antibiotics. 34:1608-1612
Tetaine induced the lysis of Escherichia coli cells. Several di- and tripeptides were found to protect this cells against tetaine action. Certain peptides are able to diminish the inhibition by tetaine of diaminopimelic acid incorporation into peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047604eb50afcb28253f646615d59656
https://doi.org/10.7164/antibiotics.34.1608
https://doi.org/10.7164/antibiotics.34.1608
Autor:
Hans Zähner, Henryk Chmara
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 787:45-52
Incubation of anticapsin with the purified glucosamine synthetase (2-amino-2-deoxy- d -glucose-6-phosphate ketol-isomerase, amino transferring, EC 5.3.1.19) from Escherichia coli , Pseudomonas aeruginosa , Arthrobacter aurescens and Bacillus thuringi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be7b599a81d57626058d2a1e97da91e9
https://doi.org/10.1016/0167-4838(84)90106-7
https://doi.org/10.1016/0167-4838(84)90106-7
Publikováno v:
Archives of Microbiology. 135:130-136
The mycelial (M) form of Candida albicans is more sensitive to the action of the antibiotic tetaine than the yeast (Y) form. Tetaine, at low concentrations about 1 microgram/ml also inhibits Y-M transition. It causes severe deformation of cells, aggl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d212f3b7430ead96d38c6a86ffa91941
https://doi.org/10.1007/bf00408022
https://doi.org/10.1007/bf00408022