Výsledky vyhledávání - "Henry Z. Markus"

Expression and Purification of Recombinant Tick Anticoagulant Peptide (Y1W/D10R) Double Mutant Secreted bySaccharomyces cerevisiae

Autor: Loren D. Schultz, Shi-Shan Mao, Charlotte C Ip, Jin Huang, Hugh A. George, Mohinder K. Sardana, Joseph G. Joyce, E. Dale Lehman, James C. Cook, William J. Miller, Henry Z. Markus, Wayne K. Herber

Publikováno v: Protein Expression and Purification. 13:291-300

A double mutant of tick anticoagulant peptide (TAP) was cloned as a chimeric fusion with the yeast α-mating factor pre-proleader peptide. Expression in yeast ( Saccharomyces cerevisiae ) resulted in the secretion of the TAP mutein into the culture m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132228cbebb0f6bb5267a0c67d7ac187
https://doi.org/10.1006/prep.1998.0893

Zobrazit plný text záznamu

Vaccination with yeast-expressed cottontail rabbit papillomavirus (CRPV) virus-like particles protects rabbits from CRPV-induced papilloma formation

Autor: James C. Cook, Alan R. Shaw, Henry Z. Markus, Loren D. Schultz, Kathrin U. Jansen, Ronald W. Ellis, John J. Donnelly, Mark Rosolowsky, Douglas Martinez

Publikováno v: Vaccine. 13:1509-1514

Papillomaviruses infect epithelia of the skin and mucous membranes and cause benign or malignant tumours in animals and in humans. The viruses are highly species-specific, and cell culture systems for propagating human papillomaviruses (HPVs) do not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002824026a57bb2eb20db2d9d485796c
https://doi.org/10.1016/0264-410x(95)00103-8

Zobrazit plný text záznamu

Purification and characterization of human plasminogen activator inhibitor type I expressed in Saccharomyces cerevisiae

Autor: Schultz Loren D, Henry Z. Markus, Ronald W. Ellis, Timothy R. Hare, Stephen J. Gardell, Jang H. Han, Christine E. Carty, Bernice J. Keech

Publikováno v: Archives of Biochemistry and Biophysics. 278:467-474

The rapidly acting inhibitor of plasminogen activators, PAI-1, was produced intracellularly in Saccharomyces cerevisiae by using the ADH2 promoter to drive the expression of the human PAI-1 cDNA. Approximately 8 mg of human PAI-1 was produced per lit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb52441f4e117785c0f5e98c4e043d30
https://doi.org/10.1016/0003-9861(90)90286-8

Zobrazit plný text záznamu

Human papillomavirus type 11 (HPV-11) neutralizing antibodies in the serum and genital mucosal secretions of African green monkeys immunized with HPV-11 virus-like particles expressed in yeast

Autor: William M. Hurni, Darron R. Brown, Henry Z. Markus, Janine T. Bryan, E. Dale Lehman, Kathryn J. Hofmann, Schultz Loren D, Cook James C, Alan R. Shaw, Robert S. Lowe, Joseph G. Joyce, Neeper Michael P, Kathrin U. Jansen, George Hugh A

Publikováno v: The Journal of infectious diseases. 176(5)

It has been shown previously that immunization of animals with recombinant virus-like particles (VLPs) consisting of the viral capsid proteins L1 or L1 plus L2 protected animals against experimental viral challenge. However, none of these experimenta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d523fe9b62f74f0b1a8424c22e35b84
https://pubmed.ncbi.nlm.nih.gov/9359711

Zobrazit plný text záznamu

Sequence conservation within the major capsid protein of human papillomavirus (HPV) type 18 and formation of HPV-18 virus-like particles in Saccharomyces cerevisiae

Autor: Kathrin U. Jansen, Henry Z. Markus, Neeper Michael P, Martin Müller, Darron R. Brown, Kathryn J. Hofmann

Publikováno v: The Journal of general virology. 77

The major capsid protein L1 of human papillomaviruses (HPVs) has been identified as a promising candidate antigen for a prophylactic HPV vaccine. Since amino acid sequence heterogeneity has been demonstrated for the L1 genes within individual HPV typ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be206f08a4a07802db841468142d373a
https://pubmed.ncbi.nlm.nih.gov/8601783

Zobrazit plný text záznamu

Expression, purification and characterization of multigram amounts of a recombinant hybrid HV1-HV2 hirudin variant expressed in Saccharomyces cerevisiae

Autor: William J. Miller, Schultz Loren D, E.D. Lehman, Joseph G. Joyce, M.A. Jacobson, Henry Z. Markus, Fred J. Bailey, C.T. Dunwiddie

Publikováno v: Protein expression and purification. 4(3)

Hirudin (HIR), derived from leeches, and tick anticoagulant peptide (TAP) are polypeptide protease inhibitors of thrombin and coagulation factor Xa (fXa), respectively, and they have both shown utility in vitro and in vivo as potent antithrombotic ag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ee526ecd3f857296c1d33a0dec917c
https://pubmed.ncbi.nlm.nih.gov/8518563

Zobrazit plný text záznamu

A novel single-dose delivery system for vaccines

Autor: Buynak Eb, Robert E. Weibel, William J. McAleer, Victor M. Villarejos, Maurice R. Hilleman, Henry Z. Markus, Arlene A. McLean

Publikováno v: Journal of Biological Standardization. 10:329-333

A single-dose, low-cost vaccine delivery system (Ezeject®) consisting of lyophilized measles (Moraten—Attenuvax®) vaccine loaded into a pre-filled single-dose plastic syringe with a squeezable body portion has been developed in these laboratories

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1873a664a3ca166e6b24b7ea98cf9b5f
https://doi.org/10.1016/s0092-1157(82)80009-7

Zobrazit plný text záznamu

Vaccine against Human Hepatitis B Virus Prepared from Antigen Derived from Human Hepatoma Cells in Culture

Autor: Eugene B. Buynak, Arlene A. McLean, William J. McAleer, Robert E. Weibel, D. Eugene Wampler, Maurice R. Hilleman, Henry Z. Markus, William J. Miller

Publikováno v: Experimental Biology and Medicine. 175:314-319

Vaccine against human hepatitis B was prepared using antigen derived from hepatitis B carrier hepatoma cells grown in the interstices of a Diaflo hollow filter unit. Hepatitis B surface antigen (HBsAg) produced by these cells was purified by immune a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a33f1c2c1617d70b225d9364678e2eb
https://doi.org/10.3181/00379727-175-41801

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání