Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Henry Tomasiewicz"'
Autor:
Henry Tomasiewicz, Barbara Goldberg, Rekha Shukla, Michael Pickart, Zhihuo Luo, Daniel N. Weber, Michael J. Carvan, Renee A. Hesselbach, Craig A. Berg, David H. Petering
Publikováno v:
The Journal of STEM Outreach. 4
The objective of our program is to foster and facilitate authentic research experiences in middle and high school science courses. We do so by providing students with a complete experience in scientific experimentation and communication. The centerpi
Autor:
Michael J. Carvan, Craig A. Berg, Renee A. Hesselbach, Barbara Goldberg, David H. Petering, Henry Tomasiewicz
Publikováno v:
Zebrafish. 11:384-395
Developing zebrafish embryos were used as a model system for high school students to conduct scientific investigations that reveal features of normal development and to test how different environmental toxicants impact the developmental process. The
Publikováno v:
Inorganic chemistry. 54(24)
Fluorescent zinc sensors are the most commonly used tool to study the intracellular mobile zinc status within cellular systems. Previously, we have shown that the quinoline-based sensors Zinquin and 6-methoxy-8-p-toluenesulfonamido-quinoline (TSQ) pr
Publikováno v:
Inorganic Chemistry. 50:7563-7573
Zn(2+) is a necessary cofactor for thousands of mammalian proteins. Research has suggested that transient fluxes of cellular Zn(2+) are also involved in processes such as apoptosis. Observations of Zn(2+) trafficking have been collected using Zn(2+)
Publikováno v:
2015 IEEE Great Lakes Biomedical Conference (GLBC).
A wide range of species, from chickens to pigs have been used as model systems for studying spinal deformities. However most of these models focus on the etiology of the problem, and few studies examine the effects of spinal deformities on locomotion
Autor:
Henry Tomasiewicz, John G. Wood
Publikováno v:
Cell Motility and the Cytoskeleton. 44:155-167
Although microtubules are known to play an important role in many cellular processes, they have been virtually neglected in fish. In this report, microtubule-associated proteins (MAPs) in fish (teleost) were characterized using antibodies (Abs) direc
Autor:
Henry Tomasiewicz, Susan M. Dymecki
Publikováno v:
Developmental Biology. 201:57-65
Here we demonstrate how a Flp recombinase-based tagging system can be used to link temporally distinct developmental events in the mouse. By directly following Flp-mediated DNA rearrangements we have analyzed the adult expansion of embryonic neural p
Autor:
Rémi Quirion, Urs Rutishauser, Terry Magnuson, Joseph Rochford, Lalit K. Srivastava, Graham K. Wood, Henry Tomasiewicz
Publikováno v:
NeuroReport. 9:461-466
NCAM-180 knockout mice, which have documented deficits in neural migration, were used to determine whether developmental abnormalities could lead to morphological changes and alterations in sensory motor gating mechanisms. Measurement of the lateral
Publikováno v:
Neuron. 16(4):735-743
Transplantation studies have been used to show that tangential migration of olfactory bulb interneuron precursors is retarded in NCAM-mutant mice, and that this defect reflects loss of NCAM polysialic acid (PSA). In contrast, radial migration of cell
Publikováno v:
Neuron. 13:595-609
The mutation of N-CAM in mice produces a phenotype dominated by an undersized olfactory bulb and accumulation of precursors in the subependymal layer. We demonstrate here that this defect can be duplicated by injection of an enzyme that specifically