Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Henry Sunpath"'
Autor:
Tamlyn A. Rautenberg, Shu Kay Ng, Gavin George, Mahomed-Yunus S. Moosa, Suzanne M. McCluskey, Rebecca F. Gilbert, Selvan Pillay, Isaac Aturinda, Kevin L. Ard, Winnie R. Muyindike, Nicholas Musinguzi, Godfrey Masette, Melendhran Pillay, Pravi Moodley, Jaysingh Brijkumar, Rajesh T. Gandhi, Brent Johnson, Henry Sunpath, Mwebesa B. Bwana, Vincent C. Marconi, Mark J. Siedner
Publikováno v:
Health and Quality of Life Outcomes, Vol 21, Iss 1, Pp 1-8 (2023)
Abstract Background Antiretroviral treatment improves health related quality of life (HRQoL) of people with human immunodeficiency virus (PWH). However, one third initiating first-line treatment experience virological failure and the determinants of
Externí odkaz:
https://doaj.org/article/d2b188a0d0b546e59e050e2059d1f1ea
Autor:
Collins Iwuji, Meg Osler, Lusanda Mazibuko, Natalia Hounsome, Nothando Ngwenya, Rujeko Samanthia Chimukuche, Thandeka Khoza, Dickman Gareta, Henry Sunpath, Andrew Boulle, Kobus Herbst
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background There is poor viral load monitoring (VLM) and inadequate management of virological failure in HIV-positive individuals on antiretroviral therapy in rural KwaZulu-Natal, South Africa. This could be contributing to increasing HIV dr
Externí odkaz:
https://doaj.org/article/e64abf9e2eaa46c9a60ec88858971779
Publikováno v:
Southern African Journal of HIV Medicine, Vol 22, Iss 1, Pp e1-e4 (2021)
In many ways, the coronavirus disease 2019 (COVID-19) pandemic mirrors the challenges, lessons and opportunities of the HIV pandemic. In this article, we argue that global pandemics such as COVID-19 and HIV require a global response. We highlight the
Externí odkaz:
https://doaj.org/article/1ee1e956895f43a9a79a5cfa3b5aa9de
Autor:
Chang Liu, Zicheng Wang, Qin Hui, Yiyun Chiang, Junyu Chen, Jaysingh Brijkumar, Johnathan A. Edwards, Claudia E. Ordonez, Mathew R. Dudgeon, Henry Sunpath, Selvan Pillay, Pravi Moodley, Daniel R. Kuritzkes, Mohamed Y. S. Moosa, Dean P. Jones, Vincent C. Marconi, Yan V. Sun
Publikováno v:
Metabolites, Vol 12, Iss 7, p 624 (2022)
Genome-wide association studies (GWAS) of circulating metabolites have revealed the role of genetic regulation on the human metabolome. Most previous investigations focused on European ancestry, and few studies have been conducted among populations o
Externí odkaz:
https://doaj.org/article/bf1d74c523884a97babc8a57fa42f3ec
Autor:
Soo-Yon Rhee, Vici Varghese, Susan P. Holmes, Gert U. Van Zyl, Kim Steegen, Mark A. Boyd, David A. Cooper, Sabin Nsanzimana, Shanmugam Saravanan, Charlotte Charpentier, Tulio de Oliveira, Mary-Ann A. Etiebet, Federico Garcia, Dominique Goedhals, Perpetua Gomes, Huldrych F. Günthard, Raph L. Hamers, Christopher J Hoffmann, Gillian Hunt, Awachana Jiamsakul, Pontiano Kaleebu, Phyllis Kanki, Rami Kantor, Bernhard Kerschberger, Vincent C. Marconi, Jean D'amour Ndahimana, Nicaise Ndembi, Nicole Ngo-Giang-Huong, Casper Rokx, Maria M. Santoro, Jonathan M. Schapiro, Daniel Schmidt, Lillian Seu, Kim C.E. Sigaloff, Sunee Sirivichayakul, Lindiwe Skhosana, Henry Sunpath, Michele Tang, Chunfu Yang, Sergio Carmona, Ravindra K. Gupta, Robert W. Shafer
Publikováno v:
EBioMedicine, Vol 18, Iss C, Pp 225-235 (2017)
Tenofovir disoproxil fumarate (TDF) genotypic resistance defined by K65R/N and/or K70E/Q/G occurs in 20% to 60% of individuals with virological failure (VF) on a WHO-recommended TDF-containing first-line regimen. However, the full spectrum of reverse
Externí odkaz:
https://doaj.org/article/c8c4f508a28b4db2b1253f3f557db59d
Autor:
Sinaye Ngcapu, Kristof Theys, Pieter Libin, Vincent C. Marconi, Henry Sunpath, Thumbi Ndung’u, Michelle L. Gordon
Publikováno v:
Viruses, Vol 9, Iss 11, p 330 (2017)
The South African national treatment programme includes nucleoside reverse transcriptase inhibitors (NRTIs) in both first and second line highly active antiretroviral therapy regimens. Mutations in the RNase H domain have been associated with resista
Externí odkaz:
https://doaj.org/article/4a29a963646e48e89bfd82ae372adc67
Publikováno v:
PLoS ONE, Vol 8, Iss 12 (2013)
[This corrects the article DOI: 10.1371/journal.pone.0044793.].
Externí odkaz:
https://doaj.org/article/51537f4f4f564abf8b54a385f1227bbf
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44793 (2012)
In HIV-infected patients receiving rifampicin-based treatment for tuberculosis (TB), the dosage of lopinavir/ritonavir (LPV/r) is adjusted to prevent sub-therapeutic lopinavir concentrations. In this setting, South African clinicians were advised to
Externí odkaz:
https://doaj.org/article/c043f49c01e84dbb8902613a34911ded
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49591 (2012)
With improved access to pediatric antiretroviral therapy (ART) in resource-limited settings, more children could experience first-line ART treatment failure.We performed a retrospective cohort analysis using electronic medical records from HIV-infect
Externí odkaz:
https://doaj.org/article/7fcbded8488745b2a801e4cd79e7695d
Autor:
Boris Julg, Danielle Poole, Musie Ghebremichael, Carmen Castilla, Marcus Altfeld, Henry Sunpath, Richard A Murphy, Bruce D Walker
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31161 (2012)
Factors predicting suboptimal CD4 cell recovery have been studied in HIV clade-B infected US and European populations. It is, however, uncertain to what extent these results are applicable to HIV clade-C infected African populations. Multivariate ana
Externí odkaz:
https://doaj.org/article/51d1d995be35480aa721e1a4c4d1c44d