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Abstract 194: Frequency of Mononuclear Diploid Cardiomyocytes Underlies Natural Variation in Heart Regeneration

Publikováno v: Circulation Research. 121

Strong evidence from the literature supports the model that mononuclear, diploid cardiomyocytes (MNDCMs), a relatively rare population in the adult mammalian heart, are a regeneration-competent population, but this has not previously been subjected t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b98bc21626f0a1e93d48fec58abee6b2
https://doi.org/10.1161/res.121.suppl_1.194

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Abstract 237: PRMT1-p53-Slug Axis Regulates Epicardial EMT and Ventricular Development

Autor: Olan Jackson-Weaver, Jian Wu, Yongchao Gou, Yibu Chen, Meng Li, Henry Sucov, Jian Xu

Publikováno v: Circulation Research. 121

Rationale: Epicardial epithelial-to-mesenchymal trasition (EMT) is a vital process in embryonic heart development. During EMT, epicardial cells acquire migratory and invasive properties, and differentiate into new cell types, including cardiac fibrob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c979bb7a08d53cc0bb21a0bd6d1930c5
https://doi.org/10.1161/res.121.suppl_1.237

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Abstract 130: Epicardial-to-Myocyte Hypertrophic Signaling is Mediated by Epicardial/Mesenchymal Status and Protein Arginine Methyltransferase-1

Autor: Olan Jackson-Weaver, Henry Sucov, Jian Xu

Publikováno v: Circulation Research. 117

The epithelial-to-mesenchymal transition (EMT) is an important cellular mechanism in a diverse range of biological processes such as development, wound healing, cancer metastasis, and organ fibrosis. Epicardial cells are mesothelial cells lining the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a48ed8a3fca9c53e1112ffe9ec1902d3
https://doi.org/10.1161/res.117.suppl_1.130

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