Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Henry R. Askew"'
Autor:
T. C. Stevenson Keller, Christophe Lechauve, Alexander S. Keller, Gilson Brás Broseghini-Filho, Joshua T. Butcher, Henry R. Askew Page, Aditi Islam, Zhe Yin Tan, Leon J. DeLalio, Steven Brooks, Poonam Sharma, Kwangseok Hong, Wenhao Xu, Alessandra Simão Padilha, Claire A. Ruddiman, Angela K. Best, Edgar Macal, Daniel B. Kim-Shapiro, George Christ, Zhen Yan, Miriam M. Cortese-Krott, Karina Ricart, Rakesh Patel, Timothy P. Bender, Swapnil K. Sonkusare, Mitchell J. Weiss, Hans Ackerman, Linda Columbus, Brant E. Isakson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
In mammals, hypoxia causes dilation of small arteries for increased metabolic demand. Keller et al used novel transgenic mice to show alpha hemoglobin in endothelium, once thought only in red blood cells, can regulate hypoxic-mediated dilation.
Externí odkaz:
https://doaj.org/article/b9f465340f0741ff838bff1e07d81c95
Akademický článek
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Autor:
Henry R. Askew Page, Samuel N. Baldwin, Onur Cil, Alan S. Verkman, Kenneth P. Roos, Pyone Myat Thwe, Peter M. Haggie, Iain A. Greenwood, Marc O. Anderson, Maria C. Jordan, Xiaolan Chen
Publikováno v:
Kidney international, vol 100, iss 2
Kidney Int
Kidney Int
Hypertension is a major cause of cardiovascular morbidity and mortality, despite the availability of antihypertensive drugs with different targets and mechanisms of action. Here, we provide evidence that pharmacological inhibition of TMEM16A (ANO1),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf8826a854b2a42c909c572d902841a
https://escholarship.org/uc/item/0q2931m3
https://escholarship.org/uc/item/0q2931m3
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Onur Cil, Maria C. Jordan, Pyone Myat Thwe, Iain A. Greenwood, Marc O. Anderson, Henry R. Askew Page, Kenneth P. Roos, Samuel N. Baldwin, Alan S. Verkman
Publikováno v:
Hypertension. 76
Hypertension is a major cause of cardiovascular morbidity and mortality, despite the availability of antihypertensive drugs with different targets and mechanisms of action. There is an unmet need for antihypertensive drugs with novel mechanisms of ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f91d49376c641e95417cb577784ad9ef
https://doi.org/10.1161/hyp.76.suppl_1.mp30
https://doi.org/10.1161/hyp.76.suppl_1.mp30
Autor:
Henry R. Askew-Page, Lauren A Biwer, Jenna Milstein, Swapnil K. Sonkusare, Scott R. Johnstone, Kwangseok Hong, Brant E. Isakson, Edgar Macal, Pooneh Bagher, Miranda E. Good
Publikováno v:
Am J Physiol Heart Circ Physiol
Discrete calcium signals within the vascular endothelium decrease with age and contribute to impaired endothelial-dependent vasodilation. Calreticulin (Calr), a multifunctional calcium binding protein and endoplasmic reticulum (ER) chaperone, can med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3c1053669f9e44fe65b9891f5edd05
https://europepmc.org/articles/PMC7346539/
https://europepmc.org/articles/PMC7346539/
Autor:
Scott R. Johnstone, Brant E. Isakson, Frank Beier, Matteo Ottolini, Mabruka Alfaidi, Stefanie Redemann, Silvia Penuela, Henry R. Askew-Page, Abigail G. Wolpe, Swapnil K. Sonkusare, Kevin J. Barr, A. Wayne Orr
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcf5e88c54093f6f10c5ffb0c7b22dbf
https://doi.org/10.1096/fasebj.2020.34.s1.06867
https://doi.org/10.1096/fasebj.2020.34.s1.06867
Autor:
Samuel N. Baldwin, Iain A. Greenwood, Henry R. Askew Page, Søren Peter Olesen, Thomas A. Jepps, Thomas Dalsgaard, Oleksandr V. Povstyan
Publikováno v:
Br J Pharmacol
Background and Purpose: Coronary artery disease leads to ischaemic heart disease and ultimately myocardial infarction. Thus, it is important to determine the factors that regulate coronary blood flow. Ca2+‐activated chloride channels contribute to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d2fd3f9ad1adbf7dc048aaac1910cc
https://pubmed.ncbi.nlm.nih.gov/30710335
https://pubmed.ncbi.nlm.nih.gov/30710335
Autor:
Jiwang Chen, Leigh Anne Swayne, Rachel B. Weaver, Iain A. Greenwood, Mykhaylo V. Artamonov, Miranda E. Good, Alexander S. Keller, Sara A. Murphy, Silvia Penuela, Avril V. Somlyo, Henry R. Askew-Page, Angela K. Best, Ellen L. Mintz, Scott R. Johnstone, Andrew K. J. Boyce, Brant E. Isakson, Roberto F. Machado, Richard D. Minshall, T.C. Stevenson Keller, Leon J. DeLalio
Publikováno v:
Anatomy and Cell Biology Publications
Objective— Sympathetic nerve innervation of vascular smooth muscle cells (VSMCs) is a major regulator of arteriolar vasoconstriction, vascular resistance, and blood pressure. Importantly, α–adrenergic receptor stimulation, which uniquely couples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a0ac8e471e795dcd81ecdfd6d72e51
https://openaccess.sgul.ac.uk/id/eprint/112718/1/nihms979945-1.pdf
https://openaccess.sgul.ac.uk/id/eprint/112718/1/nihms979945-1.pdf
Autor:
Iain A. Greenwood, Henry R. Askew Page
This chapter focuses on the role of chloride (Cl-) channels in smooth muscle. The membrane potential of smooth muscle cells is modulated by the patency of different ion channels positioned in the cell membrane. To understand the role of Cl- in smooth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a5589b780697545181d77eaae710a31
https://doi.org/10.1201/b20699-2
https://doi.org/10.1201/b20699-2