Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Henry O'Donnell"'
Autor:
Isha Singh, Anubha Seth, Christian B. Billesbølle, Joao Braz, Ramona M. Rodriguiz, Kasturi Roy, Bethlehem Bekele, Veronica Craik, Xi-Ping Huang, Danila Boytsov, Vladimir M. Pogorelov, Parnian Lak, Henry O’Donnell, Walter Sandtner, John J. Irwin, Bryan L. Roth, Allan I. Basbaum, William C. Wetsel, Aashish Manglik, Brian K. Shoichet, Gary Rudnick
Publikováno v:
Cell, vol 186, iss 10
The serotonin transporter (SERT) removes synaptic serotonin and is the target of anti-depressant drugs. SERT adopts three conformations: outward-open, occluded, and inward-open. All known inhibitors target the outward-open state except ibogaine, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d58613557bb5172a1708dafaffcd158
https://escholarship.org/uc/item/5cg0t59n
https://escholarship.org/uc/item/5cg0t59n
Autor:
Elissa A. Fink, Conner Bardine, Stefan Gahbauer, Isha Singh, Kris White, Shuo Gu, Xiaobo Wan, Beatrice Ary, Isabella Glenn, Joseph O’Connell, Henry O’Donnell, Pavla Fajtová, Jiankun Lyu, Seth Vigneron, Nicholas J. Young, Ivan S. Kondratov, Anthony J. O’Donoghue, Yurii Moroz, Jack Taunton, Adam R. Renslo, John J. Irwin, Adolfo García-Sastre, Brian K. Shoichet, Charles S. Craik
Antiviral therapeutics to treat SARS-CoV-2 are much desired for the on-going pandemic. A well-precedented viral enzyme is the main protease (MPro), which is now targeted by an approved drug and by several investigational drugs. With the inevitable li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a54cce0adbd99c2d1934399aea5fb9c
https://doi.org/10.1101/2022.07.05.498881
https://doi.org/10.1101/2022.07.05.498881
Autor:
Isha Singh, Anubha Seth, Christian B. Billesbølle, Joao Braz, Ramona M. Rodriguiz, Kasturi Roy, Bethlehem Bekele, Veronica Craik, Xi-Ping Huang, Danila Boytsov, Parnian Lak, Henry O’Donnell, Walter Sandtner, Bryan L. Roth, Allan I. Basbaum, William C. Wetsel, Aashish Manglik, Brian K. Shoichet, Gary Rudnick
SUMMARYThe serotonin transporter (SERT) removes synaptic serotonin and is the target of anti-depressant drugs. SERT adopts three conformations: outward-open, occluded, and inward-open. All known inhibitors target the outward-open state except ibogain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5895a65a89afbdc8ac539061b017cdf2
https://doi.org/10.1101/2022.06.13.495991
https://doi.org/10.1101/2022.06.13.495991
Autor:
Anat Levit Kaplan, Ryan T. Strachan, Joao M. Braz, Veronica Craik, Samuel Slocum, Thomas Mangano, Vanessa Amabo, Henry O’Donnell, Parnian Lak, Allan I. Basbaum, Bryan L. Roth, Brian Shoichet
Publikováno v:
Journal of medicinal chemistry, vol 65, iss 5
J Med Chem
J Med Chem
The 5-HT5A receptor (5-HT5AR), for which no selective agonists and only a few antagonists exist, remains the least understood serotonin (5-HT) receptor. A single commercial antagonist (SB-699551) has been widely used to investigate central nervous sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192ee3a80586cb56d73c824b54aae90d
https://doi.org/10.1101/2021.12.06.471449
https://doi.org/10.1101/2021.12.06.471449
Publikováno v:
Cyclopedia of Biography: A Record of the Lives of Eminent Persons; 1878, p4-4, 1/4p
Autor:
Brooks, Alasdair1 (AUTHOR)
Publikováno v:
Post-Medieval Archaeology. Jun2022, Vol. 56 Issue 1, p28-42. 15p.
Publikováno v:
Direct Marketing News. Apr2014, Vol. 36 Issue 4, p46-45. 2p.
Autor:
Fink, Elissa A., Bardine, Conner, Gahbauer, Stefan, Singh, Isha, Detomasi, Tyler C., White, Kris, Gu, Shuo, Wan, Xiaobo, Chen, Jun, Ary, Beatrice, Glenn, Isabella, O'Connell, Joseph, O'Donnell, Henry, Fajtová, Pavla, Lyu, Jiankun, Vigneron, Seth, Young, Nicholas J., Kondratov, Ivan S., Alisoltani, Arghavan, Simons, Lacy M.
Publikováno v:
Protein Science: A Publication of the Protein Society; Aug2023, Vol. 32 Issue 8, p1-24, 24p
Publikováno v:
Direct Marketing News. Feb2014, Vol. 36 Issue 2, p50-50. 2/3p.