Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Henry N Yu"'
Publikováno v:
Frontiers in Endocrinology, Vol 6 (2015)
Glycoprotein hormones, follicle-stimulating hormone (FSH), luteinizing hormone (LH), and thyroid stimulating hormone (TSH) are heterodimeric proteins with a common subunit and hormone-specific subunit. These hormones are dominant regulato
Externí odkaz:
https://doaj.org/article/45eeb62a5ffa44859c25d8fab5a8df6d
Autor:
Niamh S. Sayers, Priyanka Anujan, Henry N. Yu, Stephen S. Palmer, Jaya Nautiyal, Stephen Franks, Aylin C. Hanyaloglu
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2022)
Follicle-stimulating hormone (FSH) and its G protein-coupled receptor, FSHR, represents a paradigm for receptor signaling systems that activate multiple and complex pathways. Classically, FSHR activates Gαs to increase intracellular levels of cAMP,
Externí odkaz:
https://doaj.org/article/68b2b6b7698f46bb95b942fa91ee3022
Autor:
Silvia Sposini, Francesco De Pascali, Rachel Richardson, Niamh S. Sayers, David Perrais, Henry N. Yu, Stephen Palmer, Selva Nataraja, Eric Reiter, Aylin C. Hanyaloglu
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Follicle-stimulating hormone receptor (FSHR) is a G protein-coupled receptor (GPCR) with pivotal roles in reproduction. One key mechanism dictating the signal activity of GPCRs is membrane trafficking. After binding its hormone FSH, FSHR undergoes in
Externí odkaz:
https://doaj.org/article/e23f5dba43fd4c0eb3ef91dc52330195
Autor:
Francesco De Pascali, Mohammed Akli Ayoub, Riccardo Benevelli, Silvia Sposini, Jordan Lehoux, Nathalie Gallay, Pauline Raynaud, Flavie Landomiel, Frédéric Jean-Alphonse, Christophe Gauthier, Lucie P. Pellissier, Pascale Crépieux, Anne Poupon, Asuka Inoue, Nicolas Joubert, Marie-Claude Viaud-Massuard, Livio Casarini, Manuela Simoni, Aylin C. Hanyaloglu, Selva G. Nataraja, Henry N. Yu, Stephen S. Palmer, Romain Yvinec, Eric Reiter
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9850 (2021)
Follicle-stimulating hormone receptor (FSHR) plays a key role in reproduction through the activation of multiple signaling pathways. Low molecular weight (LMW) ligands composed of biased agonist properties are highly valuable tools to decipher comple
Externí odkaz:
https://doaj.org/article/f144abbebe294986baabcf655018a84f
Autor:
Niamh S, Sayers, Priyanka, Anujan, Henry N, Yu, Stephen S, Palmer, Jaya, Nautiyal, Stephen, Franks, Aylin C, Hanyaloglu
Publikováno v:
Frontiers in endocrinology. 12
Follicle-stimulating hormone (FSH) and its G protein-coupled receptor, FSHR, represents a paradigm for receptor signaling systems that activate multiple and complex pathways. Classically, FSHR activates Gαs to increase intracellular levels of cAMP,
Autor:
Selvaraj Nataraja, Henry N Yu, Claire L. Newton, Sharika Hanyroup, Ross Anderson, Robert P. Millar
Publikováno v:
Endocrinology. 162(12)
Mutations in G protein-coupled receptors (GPCRs) underlie numerous diseases. Many cause receptor misfolding and failure to reach the cell surface. Pharmacological chaperones are cell-permeant small molecules that engage nascent mutant GPCRs in the en
Publikováno v:
Angewandte Chemie. 117:7903-7907
Publikováno v:
Angewandte Chemie International Edition; Jul2005, Vol. 44 Issue 29, p4596-4599, 4p