Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Henry N, Nguyen"'
Autor:
Todd Kinsella, Scott K. Powers, Kathy White, Taisei Kinoshita, Tarikere Gururaja, George C. Yam, Kurt J. Sollanek, Donald G. Payan, Vanessa Taylor, John McLaughlin, Wayne Lang, Rongxian Ding, Baljit K. Singh, Mark D. Claypool, Marina Gelman, Derek Hansen, Ira J. Smith, Stephanie Yung, Ashley J. Smuder, Yan Chen, Kelly McCaughey, Raniel Alcantara, Wei Li, Rajinder Singh, Oh Sung Kwon, Guillermo Godinez, Jason Romero, Michael P. Wiggs, Esteban Masuda, Henry N. Nguyen, Annabelle M. Friera, Melissa S. Ho, Kristen Baltgalvis, Daniel P. Creger
Publikováno v:
The FASEB Journal
Controlled mechanical ventilation (CMV) is associated with the development of diaphragm atrophy and contractile dysfunction, and respiratory muscle weakness is thought to contribute significantly to delayed weaning of patients. Therefore, therapeutic
Publikováno v:
Journal of Alzheimer's Disease. 17:369-382
Donepezil, an acetylcholinesterase (AChE) inhibitor used for treating Alzheimer's disease patients, is thought to act by increasing brain extracellular acetylcholine (ACh), and ACh binding to cholinergic receptors. Muscarinic receptors are coupled to
Autor:
Dede Greenstein, Mei Chen, Lisa Chang, Mireille Basselin, Stanley I. Rapoport, Henry N. Nguyen
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 29:648-658
Nicotine exerts its central effects by activating pre- and postsynaptic nicotinic acetylcholine receptors (nAChRs). Presynaptic nAChRs modulate the release of many neurotransmitters that bind to postsynaptic receptors. These may be coupled to the act
Publikováno v:
Journal of Neurochemistry. 90:40-49
Chronic nicotine exposure up-regulates neuronal nicotinic receptors, but the functional consequences for these receptors is less well understood. Following 2 weeks of nicotine or saline treatment by osmotic minipump, the functional activity of nicoti
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 22:206-214
To determine the role of calcium homeostasis in ischemic neuronal death, the authors used an in vitro model of oxygen–glucose deprivation in neuronal cell lines. Exposure of human neuroblastoma SH-SY5Y cells to 10- to 16-hour oxygen–glucose depri
Publikováno v:
Brain Research. 924:159-166
Inhibiting Ca(2+) uptake by the sarcoendoplasmic reticular Ca(2+)-ATPase pump (SERCA) causes release of Ca(2+) from the endoplasmic reticulum (ER), increased cytosolic Ca(2+) ([Ca(2+)](cyt)) and depletion of ER Ca(2+) stores. These studies were desig
Publikováno v:
Journal of neurochemistry. 90(1)
Chronic nicotine exposure up-regulates neuronal nicotinic receptors, but the functional consequences for these receptors is less well understood. Following 2 weeks of nicotine or saline treatment by osmotic minipump, the functional activity of nicoti
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 307(3)
Subtypes of neuronal nicotinic acetylcholine receptors (nAChRs) are differentially sensitive to up-regulation by chronic nicotine exposure in vitro. To determine whether this occurs in animals, rats were implanted with minipumps containing saline +/-
Autor:
David C, Perry, Yingxian, Xiao, Henry N, Nguyen, John L, Musachio, Martha I, Dávila-García, Kenneth J, Kellar
Publikováno v:
Journal of neurochemistry. 82(3)
Comparison of [125I]epibatidine and 5-[125I]iodo-3-(2-azetidinylmethoxy)pyridine ([125I]A-85380) autoradiography showed evidence for nicotinic receptor heterogeneity. To identify the receptor subtypes, we performed [125I]epibatidine autoradiography i
Autor:
Coronnello, Claudia1,2 clc196@pitt.edu, Hartmaier, Ryan3, Arora, Arshi1, Huleihel, Luai4, Pandit, Kusum V.4, Bais, Abha S.1, Butterworth, Michael5, Kaminski, Naftali4, Stormo, Gary D.6, Oesterreich, Steffi3, Benos, Panayiotis V.1,7 benos@pitt.edu
Publikováno v:
PLoS Computational Biology. Dec2012, Vol. 8 Issue 12, p1-13. 13p. 1 Diagram, 4 Graphs.