Výsledky vyhledávání - "Henry M. Wisniewski"

Plasma amyloid ?-peptide 1-42 and incipient Alzheimer's disease

Autor: Henry M. Wisniewski, Diane M. Jacobs, Pankaj D. Mehta, Scott A. Small, Yaakov Stern, Jennifer J. Manly, Carol Merchant, Karen L. Bell, Ming-Xin Tang, Richard Mayeux

Publikováno v: Annals of Neurology. 46:412-416

Mutations in the amyloid precursor protein and presenilin 1 and 2 genes result in elevated plasma levels of the amyloid beta-peptide species terminating at amino acid residue 42 (A beta1-42). In a longitudinal study of unrelated elderly individuals,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::acdb339ed2785020af850eefe99bfc90
https://doi.org/10.1002/1531-8249(199909)46:3<412::aid-ana19>3.0.co

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The therapeutic effect of an herbal formula Badmaev 28 (Padma 28) on experimental allergic encephalomyelitis (EAE) in SJL/J mice

Autor: Henry M. Wisniewski, Georgia B. Schuller-Levis, P. B. Kozlowski, Vladimir Badmaev

Publikováno v: Phytotherapy Research. 13:218-221

A herbal formula, Badmaev 28, was evaluated in the treatment of an induced attack in a chronic relapsing model of experimental allergic encephalomyelitis (EAE) in SJL/J mice. Chronic EAE was induced by immunization of 8 week old mice with an emulsion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ed3bc967fa346f1b83e4065d927a5d6a
https://doi.org/10.1002/(sici)1099-1573(199905)13:3<218::aid-ptr426>3.0.co

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Characterization of a strain of cerebral endothelial cells derived from goat brain which retain their differentiated traits after long-term passage

Autor: Xiu-Lan Yao, Edmund C. Jenkins, Richard S. Trowbridge, Wei Quan, Thomas D. Bunch, Alma Maciulis, Henry M. Wisniewski, Louis Faso

Publikováno v: In Vitro Cellular & Developmental Biology - Animal. 30:226-235

A strain of cerebral endothelial cells was established from isolated cortical microvessels of caprine brain. These cells, which are referred to as EC1 cells, can be routinely subcultured to 32 passages without the loss of differentiated morphologic a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2242b5edd00d60c67e8f93112f3b145b
https://doi.org/10.1007/bf02632044

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Pathology of Alzheimer's Disease

Autor: Henry M. Wisniewski, B.V.M. Li-wen Ko, Blass Jp

Publikováno v: Psychiatric Clinics of North America. 14:397-420

The fundamental pathophysiology of Alzheimer's disease remains poorly understood, but progress has been dramatic in description of the pathology at the molecular level. The characteristic Alzheimer amyloid derives, in part, by action of microglia, fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5bf5a5fbf8067eb4245ee4e0c5690132
https://doi.org/10.1016/s0193-953x(18)30315-0

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Mitochondrial dysfunction induced by oxidative stress in the brains of hamsters infected with the 263 K scrapie agent

Autor: Yong-Sun Kim, Seung Il Choi, Won-Kyu Ju, Richard I. Carp, Eun-Kyoung Choi, Jin Kim, Henry M . Wisniewski, Ho-Zoo Lea

Publikováno v: Acta neuropathologica. 96(3)

Scrapie, one of the prion diseases, is a transmissible neurodegenerative disease of sheep and other animals. Clinical symptoms of prion diseases are characterized by a long latent period, followed by progressive ataxia, tremor, and death. To study th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7aeadd2847c09a5de65a72626db6447
https://pubmed.ncbi.nlm.nih.gov/9754961

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Interaction of protein kinase C with phosphoinositides

Autor: Henry M. Wisniewski, Ved Chauhan, Abha Chauhan, Hans Brockerhoff

Publikováno v: Archives of biochemistry and biophysics. 287(2)

Calcium/phosphatidylserine-dependent protein kinase C (PKC) is activated by phosphatidylinositol 4,5-bisphosphate (PIP2), as well as by diacylglycerol (DG) and phorbol esters. Here we report that PIP2, like DG, increases the affinity of PKC for Ca2+,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61bd95f02d703f5fbc9ff9b13c8d314b
https://pubmed.ncbi.nlm.nih.gov/1654811

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Experience with prenatal fragile X detection

Autor: Henry M. Wisniewski, R. D. Rudelli, John M. Opitz, W. Ted Brown, Judith Brooks, Charlotte J. Duncan, Edmund C. Jenkins

Publikováno v: American Journal of Medical Genetics. 17:215-239

We have attempted the prenatal detection of the fra(X) 9 times. Three fra(X) positive fetuses have been diagnosed: 2 males and one female. The diagnosis on the 2 males has been confirmed. The testes of the 2 fra(X) positive fetuses appeared large for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d7d2c476ecf6a58e28fd36282ca962
https://doi.org/10.1002/ajmg.1320170114

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