Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Henry L. Keen"'
Autor:
Athmane Teghanemt, Priyanjali Pulipati, Kara Misel-Wuchter, Kenneth Day, Matthew S. Yorek, Ren Yi, Henry L. Keen, Christy Au, Thorsten Maretzky, Prajwal Gurung, Dan R. Littman, Priya D. Issuree
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Epigenetic states that are established during thymic T cell development influence functionality of mature T cells. Authors here show that early developmental programming of the Cd4 locus is comprised of DNA-demethylation at a specific stimulus-respon
Externí odkaz:
https://doaj.org/article/482db9321db34efd98079e36a3067f0a
Autor:
Venkateswaran Ganesh, Dongrim Seol, Piedad C. Gomez-Contreras, Henry L. Keen, Kyungsup Shin, James A. Martin
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 466 (2022)
Exosomes have attracted attention due to their ability to promote intercellular communication leading to enhanced cell recruitment, lineage-specific differentiation, and tissue regeneration. The object of this study was to determine the effect of exo
Externí odkaz:
https://doaj.org/article/6b4922342eb549eb9318e33e1ce15104
Autor:
Nicole K. Littlejohn, Henry L. Keen, Benjamin J. Weidemann, Kristin E. Claflin, Kevin V. Tobin, Kathleen R. Markan, Sungmi Park, Meghan C. Naber, Francoise A. Gourronc, Nicole A. Pearson, Xuebo Liu, Donald A. Morgan, Aloysius J. Klingelhutz, Matthew J. Potthoff, Kamal Rahmouni, Curt D. Sigmund, Justin L. Grobe
Publikováno v:
Cell Reports, Vol 16, Iss 6, Pp 1548-1560 (2016)
Activation of the brain renin-angiotensin system (RAS) stimulates energy expenditure through increasing of the resting metabolic rate (RMR), and this effect requires simultaneous suppression of the circulating and/or adipose RAS. To identify the mech
Externí odkaz:
https://doaj.org/article/e7234e0f403b4ffda221e675b42b26a6
Autor:
Jehan Alladina, Neal P. Smith, Tristan Kooistra, Kamil Slowikowski, Isabela J. Kernin, Jacques Deguine, Henry L. Keen, Kasidet Manakongtreecheep, Jessica Tantivit, Rod A. Rahimi, Susan L. Sheng, Nhan D. Nguyen, Alexis M. Haring, Francesca L. Giacona, Lida P. Hariri, Ramnik J. Xavier, Andrew D. Luster, Alexandra-Chloé Villani, Josalyn L. Cho, Benjamin D. Medoff
Publikováno v:
Science Immunology. 8
Asthma is a chronic disease most commonly associated with allergy and type 2 inflammation. However, the mechanisms that link airway inflammation to the structural changes that define asthma are incompletely understood. Using a human model of allergen
Publikováno v:
Microbiology resource announcements. 11(7)
Autor:
Henry L. Keen, Athmane Teghanemt, Prajwal Gurung, Priya D. Issuree, Ren Yi, Kenneth Day, Matt Yorek, Priyanjali Pulipati, Kara Misel-Wuchter, Christy Au, Thorsten Maretzky, Dan R. Littman
The potential for early thymic developmental events to program epigenetic states that influence adult T cell physiology remains an important question in health. Herein using the Cd4 locus as a paradigm for early developmental programming, we demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2750691a410b8ae832260b62304f894c
https://doi.org/10.21203/rs.3.rs-474492/v1
https://doi.org/10.21203/rs.3.rs-474492/v1
Autor:
Athmane Teghanemt, Priyanjali Pulipati, Kenneth Day, Matt Yorek, Ren Yi, Kara Misel-Wuchter, Henry L Keen, Christy Au, Thorsten Maretzky, Prajwal Gurung, Dan R. Littman, Priya D. Issuree
The repressive effect of DNA methylation at promoters is well-known. However, its role within conserved sequences in intragenic and intergenic regions is less clear. Using Cd4 as a model gene, here we show that DNA methylation regulates the function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3014e0b313628b9e65f2531cff76d2f
https://doi.org/10.1101/2021.05.03.442517
https://doi.org/10.1101/2021.05.03.442517
Autor:
Frederick W. Quelle, Curt D. Sigmund, Ko-Ting Lu, Jeffrey D. Singer, James A. McCormick, Henry L. Keen, Larry N. Agbor, Anand R. Nair, Jing Wu, Deborah R. Davis
Patients with mutations in Cullin-3 (CUL3) exhibit severe early onset hypertension but the contribution of the smooth muscle remains unclear. Conditional genetic ablation of CUL3 in vascular smooth muscle (S-CUL3KO) causes progressive impairment in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5f224eac7626721b7cc665c8365457
https://europepmc.org/articles/PMC6675584/
https://europepmc.org/articles/PMC6675584/
Autor:
Chunyan Hu, Shi Fang, Deng-Fu Guo, Masashi Mukohda, Henry L. Keen, Curt D. Sigmund, Fredrick W. Quelle, Anand R. Nair, Debbie R Davis, Stella-Rita Ibeawuchi, Xuebo Liu, Ko-Ting Lu, Larry N. Agbor, Jing Wu
Publikováno v:
The FASEB Journal. 33
Autor:
Aloysius J. Klingelhutz, Nicole K. Littlejohn, Kamal Rahmouni, Kevin V. Tobin, Justin L. Grobe, Meghan C. Naber, Nicole A Pearson, Matthew J. Potthoff, Benjamin J. Weidemann, Francoise A. Gourronc, Xuebo Liu, Kathleen R. Markan, Sungmi Park, Kristin E. Claflin, Donald A. Morgan, Henry L. Keen, Curt D. Sigmund
Publikováno v:
Cell Reports, Vol 16, Iss 6, Pp 1548-1560 (2016)
SummaryActivation of the brain renin-angiotensin system (RAS) stimulates energy expenditure through increasing of the resting metabolic rate (RMR), and this effect requires simultaneous suppression of the circulating and/or adipose RAS. To identify t