Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Henry L Wong"'
Autor:
Giuseppe Cataldo, Mary M. Lunzer, Eyup Akgün, Henry L. Wong, Philip S. Portoghese, Donald A. Simone
Publikováno v:
Neuroscience. 516:54-61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c048e45c72204f282d9c739b70b78754
https://doi.org/10.1016/j.neuroscience.2023.02.006
https://doi.org/10.1016/j.neuroscience.2023.02.006
Autor:
Erik B. Faber, Nan Wang, Kristen John, Luxin Sun, Henry L. Wong, David Burban, Rawle Francis, Defeng Tian, Kwon H. Hong, An Yang, Liming Wang, Mazen Elsaid, Hira Khalid, Nicholas M. Levinson, Ernst Schönbrunn, Jon E. Hawkinson, Gunda I. Georg
Publikováno v:
Journal of Medicinal Chemistry. 66:1928-1940
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8f7407374916699833f89e391662359
https://doi.org/10.1021/acs.jmedchem.2c01731
https://doi.org/10.1021/acs.jmedchem.2c01731
Autor:
Erik B. Faber, Nan Wang, Kristen John, Luxin Sun, David Burban, Henry L. Wong, Rawle Francis, Defeng Tian, Kwon H. Hong, An Yang, Liming Wang, Mazen Elsaid, Hira Khalid, Nicholas Levinson, Ernst Schönbrunn, Jon E. Hawkinson, Gunda Georg
Despite the status of cyclin-dependent kinase 2 (CDK2) as a validated target for both anticancer and contraceptive indications, a CDK2 inhibitor with exquisite selectivity has been historically challenging, largely due to the structural similarity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40cb086dde45184ebee3b82d2da24e6
https://doi.org/10.26434/chemrxiv-2022-4h8lf-v2
https://doi.org/10.26434/chemrxiv-2022-4h8lf-v2
Autor:
Emily Moslinger, Martin Kaufmann, Prameet M. Sheth, Henry L. Wong, Anne K. Ellis, Calvin Sjaarda, Robert I. Colautti, Sean M.P. Bennet, Stephen Vanner, Kaede Takami, Katya Douchant, David E. Reed
BackgroundRespiratory viruses are transmitted and acquired via the nasal mucosa, and thereby may influence the nasal metabolome composed of biochemical products produced by both host cells and microbes. Studies of the nasal metabolome demonstrate vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71e922f1c50eed04e1dbfd175ca7298
https://doi.org/10.1101/2021.06.18.21259150
https://doi.org/10.1101/2021.06.18.21259150
Publikováno v:
Journal of Medicinal Chemistry. 62:1684-1689
Pironetin, the only crystallographically confirmed natural product to target α-tubulin, displays potent cytotoxic activity against sensitive and resistant A2780 ovarian cancer cell lines but is only marginally active in vivo. We now report that piro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed6dfd45e73c9e892b2d1c6547d56bf9
https://doi.org/10.1021/acs.jmedchem.8b01774
https://doi.org/10.1021/acs.jmedchem.8b01774
Autor:
Robert I. Colautti, David Huang, Nazneen Rustom, Claudio N. Soares, Henry L. Wong, Calvin Sjaarda, T. Hugh Guan, Melissa Hudson, Gerald A Evans, Muhammad Ayub, Zhengxin Sun, Santiago Pérez-Patrigeon, Prameet M. Sheth
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
The emergence and rapid global spread of SARS-CoV-2 demonstrates the importance of infectious disease surveillance, particularly during the early stages. Viral genomes can provide key insights into transmission chains and pathogenicity. Nasopharyngea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b424a91db4690f25251ad6b4ea892a
Autor:
Alexander Khoruts, Henry L Wong, Melissa Weldy, Peter I. Dosa, Michael J. Sadowsky, Ali Nakhi
Publikováno v:
RSC Med Chem
Bile acid derivatives have been investigated as possible therapeutics for a wide array of conditions, including several for which gut-restricted analogs would likely be preferred. These include the prevention of Clostridioides difficile infection (CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93ebd76aa947d24a64a2584f221b184
https://pubmed.ncbi.nlm.nih.gov/34046622
https://pubmed.ncbi.nlm.nih.gov/34046622
Autor:
Valérie C. Pierre, Timothy R. DeGrado, Aditya Bansal, Henry L. Wong, Mukesh K. Pandey, Fiona Armstrong-Pavlik, M. Andrey Joaqui-Joaqui, Mandapati V. Ramakrishnam Raju, Ayca Dundar
Publikováno v:
Inorganic chemistry. 59(17)
Four tris-bidentate catecholamide (CAM) ligands were synthesized, characterized, and evaluated as ligands for radiolabeling of gallium-68 for positron emission tomography (PET). Three of those ligands, 2,2-Glu-CAM, 3,3-Glu-CAM, and TREN-bisGlyGlu-CAM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38605a2c5414d3d98eebc969e59c0bf
https://pubmed.ncbi.nlm.nih.gov/32820888
https://pubmed.ncbi.nlm.nih.gov/32820888
Autor:
Claudio N. Soares, Henry L. Wong, Santiago Pérez-Patrigeon, Prameet M. Sheth, Calvin Sjaarda, Melissa Hudson, Robert I. Colautti, Nazneen Rustom, Gerald A Evans, T. Hugh Guan, David Huang, Muhammad Ayub
The emergence and global spread of SARS-CoV-2 has had profound social and economic consequences and has shed light on the importance of continued and additional investment in global health and infectious disease surveillance. Identifying changes in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2901beaba28e3d5ae81d00d4f5cbbda2
https://doi.org/10.1101/2020.06.25.171744
https://doi.org/10.1101/2020.06.25.171744
Autor:
Joseph S. Tash, Henry L. Wong, Erick J. Carlson, Vijayalaxmi Gupta, C. Leigh Allen, Gunda I. Georg, Sheri Ann Hild, Sudhakar Jakkaraj
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 1
International Journal of Molecular Sciences, Vol 21, Iss 1, p 301 (2019)
Volume 21
Issue 1
International Journal of Molecular Sciences, Vol 21, Iss 1, p 301 (2019)
This study shows for the first time that an iminosugar exerts anti-spermiogenic effect, inducing reversible infertility in a species that is not related to C57BL/6 male mice. In CD rats, N-butyldeoxygalactonojirimycin (NB-DGJ) caused reversible infer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a08deee5969c11a461cece53df486f
http://europepmc.org/articles/PMC6982022
http://europepmc.org/articles/PMC6982022