Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Henry Jacobelli"'
Autor:
Jocelyne Puaud, Veronique Fasquelle, Ajith C. Manage, Roger Wrigglesworth, Bernard Gaudilliere, Henry Jacobelli, Matthew Badland, Ingrid Devillers, Isabelle Pevet, Corinne Durand, Anthony J. Shorter
Publikováno v:
Tetrahedron Letters. 52:5292-5296
The syntheses of various substituted azaindolines are described. Azaindolines were identified as potential key intermediates towards new PDE4 inhibitors.
Autor:
Roger Wrigglesworth, Moulay Idrissi, Ingrid Devillers, Henry Jacobelli, Isabelle Pevet, Corinne Durand, François Moreau, Bernard Gaudilliere, Veronique Fasquelle, Jocelyne Puaud
Publikováno v:
ChemInform. 35
Autor:
Eric Auclair, Veronique Fasquelle, Annette M. Doherty, Kam Chan, Stéphane Milano, Emmanuelle Lallier, Bernadette Bertin, Malika Ouagued, Marie-Noelle Rocher, Catherine Burnouf, Christèle Bigot, Brigitte Martin, Roger Wrigglesworth, Marie-Pierre Pruniaux, Richard B. Gilbertsen, Frederic Feru, Jocelyne Puaud, Nadine Avenel, Jacquie Maignel, Yves Pascal, Adel Kebsi, Calvet Alain Pierre, Henry Jacobelli, Christophe Terrasse, Corinne Durand
Publikováno v:
Journal of medicinal chemistry. 43(25)
The synthesis, structure-activity relationships, and biological properties of a novel series of potent and selective phosphodiesterase type 4 (PDE4) inhibitors are described. These new aminodiazepinoindoles displayed in vitro PDE4 activity with submi