Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Henry J. Barton"'
Publikováno v:
Genome Biology and Evolution
Sex chromosomes contribute substantially to key evolutionary processes such as speciation and adaptation. Several theories suggest that evolution could occur more rapidly on sex chromosomes, but currently our understanding of whether and how this occ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71391d319be550abcd7f72ec9c706cfa
https://doi.org/10.1093/gbe/evaa044
https://doi.org/10.1093/gbe/evaa044
Autor:
Marjaana J. Häyrinen, Jenni Kiiskilä, Annamari Ranki, Liisa Väkevä, Henry J. Barton, Milla E. L. Kuusisto, Katja Porvari, Hanne Kuitunen, Kirsi-Maria Haapasaari, Hanna-Riikka Teppo, Outi Kuittinen
Publikováno v:
Cancers
Volume 15
Issue 5
Pages: 1527
Volume 15
Issue 5
Pages: 1527
The purpose of this RNA sequencing study was to investigate the biological mechanism underlying how the transcription factors (TFs) Twist1 and Zeb1 influence the prognosis of mycosis fungoides (MF). We used laser-captured microdissection to dissect m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b6ecfb5f5e41281fd7344ad21f097e
https://doi.org/10.3390/cancers15051527
https://doi.org/10.3390/cancers15051527
Autor:
Kai Zeng, Henry J Barton
Publikováno v:
Genome Biology and Evolution
Insertions and deletions (INDELs) remain understudied, despite being the most common form of genetic variation after single nucleotide polymorphisms. This stems partly from the challenge of correctly identifying the ancestral state of an INDEL and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85960d9fa8296a02cbd97bda909e5c2a
https://doi.org/10.1093/gbe/evz068
https://doi.org/10.1093/gbe/evz068
Autor:
Henry J Barton, Kai Zeng
Understanding the determinants of genomic base composition is fundamental to understanding genome evolution. GC biased gene conversion (gBGC) is a key driving force behind genomic GC content, through the preferential incorporation of GC alleles over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a52e17a6aa831f271923a183398f37f1
https://doi.org/10.1101/2021.04.20.440602
https://doi.org/10.1101/2021.04.20.440602
Publikováno v:
Genome Biology and Evolution
Whole-genome duplications (WGD) have been considered as springboards that potentiate lineage diversification through increasing functional redundancy. Divergence in gene regulatory elements is a central mechanism for evolutionary diversification, yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5320c64dc7abca413cca18465f33db43
https://pubmed.ncbi.nlm.nih.gov/33749748
https://pubmed.ncbi.nlm.nih.gov/33749748
Publikováno v:
Genome Biology and Evolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::8b29fe55d63510321b92fab888e623c3
Whole genome duplications (WGD) have been considered as springboards that potentiate lineage diversification through increasing functional redundancy. Divergence in gene regulatory elements is a central mechanism for evolutionary diversification, yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c246fdc3ed97fcfa9ad30865741008da
https://doi.org/10.1101/2020.11.20.389684
https://doi.org/10.1101/2020.11.20.389684
Publikováno v:
Molecular Biology and Evolution
It is known that the effective population size (Ne) and the mutation rate (u) vary across the genome. Here, we show that ignoring this heterogeneity may lead to biased estimates of past demography. To solve the problem, we develop new methods for joi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156139a788c9f2d85f3e40ff389667df
https://doi.org/10.1093/molbev/msy212
https://doi.org/10.1093/molbev/msy212
Autor:
Kai Zeng, Henry J Barton
Publikováno v:
Molecular Biology and Evolution
Small insertions and deletions (INDELs; ≤50 bp) are the most common type of variability after single nucleotide polymorphism (SNP). However, compared with SNPs, we know little about the distribution of fitness effects (DFE) of new INDEL mutations a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8feb9de7c2115e773b166f44b0eb4667
https://doi.org/10.1093/molbev/msy054
https://doi.org/10.1093/molbev/msy054
Autor:
Toni I. Gossmann, Henry J Barton, Matthew C. Heatley, Christopher R. Cooney, Leeban Yusuf, Joseph P.G. Palmer
Publikováno v:
Genome Res
Recent progress has been made in identifying genomic regions implicated in trait evolution on a microevolutionary scale in many species, but whether these are relevant over macroevolutionary time remains unclear. Here, we directly address this fundam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4a0a742719463c9e1264fef079c379
https://doi.org/10.1101/844951
https://doi.org/10.1101/844951