Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Henry J Martell"'
Autor:
Divya Natesan, Li Zhang, Henry J. Martell, Tanya Jindal, Patrick Devine, Bradley Stohr, Carlos Espinosa-Mendez, James Grenert, Jessica Van Ziffle, Nancy Joseph, Sarah Umetsu, Courtney Onodera, Michelle Turski, Emily Chan, Arpita Desai, Rahul Aggarwal, Anthony Wong, Sima Porten, Jonathan Chou, Terence Friedlander, Lawrence Fong, Eric J. Small, Alejandro Sweet-Cordero, Vadim S. Koshkin
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionTumor mutational burden (TMB) and APOBEC mutational signatures are potential prognostic markers in patients with advanced urothelial carcinoma (aUC). Their utility in predicting outcomes to specific therapies in aUC warrants additional st
Externí odkaz:
https://doaj.org/article/d5d36889a09849b4bd34fd75789880d6
Autor:
Kathryn D. Sanders, Darren K. Griffin, Henry J. Martell, Joshua Blazek, Michael Large, Tony Gordon
Publikováno v:
Journal of Assisted Reproduction and Genetics. 40:653-664
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::986bd4332d7f918c8e72d2fb6e688f2d
https://doi.org/10.1007/s10815-022-02678-8
https://doi.org/10.1007/s10815-022-02678-8
Publikováno v:
BMC Genomics, Vol 18, Iss S5, Pp 47-64 (2017)
Abstract Background Cystinuria is an inherited disease that results in the formation of cystine stones in the kidney, which can have serious health complications. Two genes (SLC7A9 and SLC3A1) that form an amino acid transporter are known to be respo
Externí odkaz:
https://doaj.org/article/71c1d6b1ed034c839d8bcd01fa0ee451
Autor:
Maren van Son, Marcos S. Lopes, Henry J. Martell, Martijn F. L. Derks, Lars Erik Gangsei, Jorgen Kongsro, Mark N. Wass, Eli H. Grindflek, Barbara Harlizius
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Modern breeding schemes for livestock species accumulate a large amount of genotype and phenotype data which can be used for genome-wide association studies (GWAS). Many chromosomal regions harboring effects on quantitative traits have been reported
Externí odkaz:
https://doaj.org/article/4844aa66aed64b37ad23d575c23b699f
Autor:
Henry J. Martell, Avanthi T. Shah, Alex G. Lee, Bogdan Tanasa, Stanley G. Leung, Aviv Spillinger, Heng-Yi Liu, Inge Behroozfard, Phuong Dinh, María V. Pons Ventura, Florette K. Hazard, Arun Rangaswami, Sheri L. Spunt, Norman J. Lacayo, Tabitha Cooney, Jennifer G. Michlitsch, Anurag K. Agrawal, Marcus R. Breese, Alejandro Sweet-Cordero
Publikováno v:
Cancer Research. 83:1509-1509
For many pediatric cancer patients, commonly used gene-panel sequencing tests yield few actionable results, partly due to the complex genomic alterations present. We hypothesized that an unbiased approach, combining whole-genome (WGS) and RNA sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27b898ddfe3bc343e773f0ae5f6196c3
https://doi.org/10.1158/1538-7445.am2023-1509
https://doi.org/10.1158/1538-7445.am2023-1509
Autor:
Anya Levinson, Jessica Van Ziffle, M Dwight Chen, Jacob Pfeil, Inge Behroozfard, E. Alejandro Sweet-Cordero, Charles Zaloudek, Avanthi Tayi Shah, Stanley G. Leung, Elliot Stieglitz, Arjun A. Rao, Benjamin Laguna, Nicholas R. Ladwig, Henry J Martell, Sofie R. Salama, Alex G. Lee, Marcus R. Breese, Lee-may Chen
Publikováno v:
JCO Precision Oncology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda6e5cb23a53fecc0fc172016633116
https://doi.org/10.1200/po.20.00132
https://doi.org/10.1200/po.20.00132
Autor:
Harry Jubb, Aleksandras Gutmanas, Radka Svobodová, Stephen Anyango, Sreenath Nair, Manjeet Kumar, Jonathan D. Tyzack, Leandro G Radusky, Toby J. Gibson, Liang-Chin Huang, Luis Serrano, Eloy Villasclaras Fernandez, Sameer Velankar, Petr Škoda, Michael J.E. Sternberg, Mark N. Wass, Fábio Madeira, Christine A. Orengo, Rishabh Jain, Stuart A. MacGowan, Patrizio Di Micco, Sayoni Das, Emmanuel D. Levy, Natarajan Kannan, John M. Berrisford, Tom L. Blundell, Janet M. Thornton, Radoslav Krivak, Christos C. Kannas, Lukáš Pravda, Bissan Al-Lazikani, Jose M. Dana, Abhik Mukhopadhyay, David R. Armstrong, Saqib Mir, Mihaly Varadi, Franca Fraternali, Karel Berka, Mallur S. Madhusudhan, Jake E McGreig, Mandar Deshpande, Neera Borkakoti, Luca Parca, António J. M. Ribeiro, Ian Sillitoe, Henry J Martell, Manuela Helmer-Citterich, Sucharita Dey, David Hoksza, Gulzar Singh, Jaroslav Koča, Typhaine Paysan-Lafosse, Geoffrey J. Barton, Alfonso Valencia, Wim F. Vranken
Publikováno v:
Nucleic Acids Research
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The Protein Data Bank in Europe-Knowledge Base (PDBe-KB, https://pdbe-kb.org) is a community-driven, collaborative resource for literature-derived, manually curated and computationally predicted structural and functional annotations of macromolecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa27c0dd4bcd59db90b1d8c5a0ca1042
http://europepmc.org/articles/PMC6943075
http://europepmc.org/articles/PMC6943075
Publikováno v:
Bioinformatics. 35:3553-3558
Motivation The potential of the Bombali virus, a novel Ebolavirus, to cause disease in humans remains unknown. We have previously identified potential determinants of Ebolavirus pathogenicity in humans by analysing the amino acid positions that are d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60bc3c244e94623a9253849d31832347
https://doi.org/10.1093/bioinformatics/btz267
https://doi.org/10.1093/bioinformatics/btz267
Autor:
Henry J. Martell, Avanthi Tayi Shah, Alex G. Lee, Bogdan Tanasa, Stanley G. Leung, Aviv Spillinger, Heng-Yi Liu, Inge Behroozfard, Phuong Dinh, Maria V. Pons Ventura, Florette K. Hazard, Arun Rangaswami, Sheri L. Spunt, Norman J. Lacayo, Tabitha Cooney, Jennifer G. Michlitsch, Anurag K. Agrawal, Marcus R. Breese, E. Alejandro Sweet-Cordero
Publikováno v:
Cancer Research. 82:54-54
The use of sequencing-based assays for clinical management of pediatric cancer patients has become increasingly common. However, for many pediatric patients, gene panel based sequencing tests yield few actionable results. Given the complex genomic al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::843dc7b13c05fe588c2602731939308e
https://doi.org/10.1158/1538-7445.am2022-54
https://doi.org/10.1158/1538-7445.am2022-54
Coevolution has been widely studied between species and has an important role in our understanding of biological function. For proteins there has recently been interest in the identification of positions within proteins that have coevolved including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23e385a9bb35bc5229c1e0e8ea5d2810
https://doi.org/10.1101/2020.08.07.240887
https://doi.org/10.1101/2020.08.07.240887
