Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Henry H. Ruiz"'
Autor:
Chunxue Zhou, Henry H. Ruiz, Li Ling, Giulia Maurizi, Kenichi Sakamoto, Claudia G. Liberini, Ling Wang, Adrien Stanley, Hale E. Egritag, Sofia M. Sanz, Claudia Lindtner, Mary A. Butera, Christoph Buettner
Publikováno v:
Molecular Metabolism, Vol 78, Iss , Pp 101813- (2023)
Objective: Hepatic steatosis is a key initiating event in the pathogenesis of alcohol-associated liver disease (ALD), the most detrimental organ damage resulting from alcohol use disorder. However, the mechanisms by which alcohol induces steatosis re
Externí odkaz:
https://doaj.org/article/592fa73d8ff24ad284823221a6a6e218
Autor:
Michael MacLean, Judyta Juranek, Swetha Cuddapah, Raquel López-Díez, Henry H. Ruiz, Jiyuan Hu, Laura Frye, Huilin Li, Paul F. Gugger, Ann Marie Schmidt
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-24 (2021)
Abstract Background Burgeoning evidence highlights seminal roles for microglia in the pathogenesis of neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). The receptor for advanced glycation end products (RAGE) binds ligands rele
Externí odkaz:
https://doaj.org/article/7ce367320eaa498091fe802eed3a57b8
Autor:
Carmen Hurtado del Pozo, Henry H. Ruiz, Lakshmi Arivazhagan, Juan Francisco Aranda, Cynthia Shim, Peter Daya, Julia Derk, Michael MacLean, Meilun He, Laura Frye, Randall H. Friedline, Hye Lim Noh, Jason K. Kim, Richard A. Friedman, Ravichandran Ramasamy, Ann Marie Schmidt
Publikováno v:
Cell Reports, Vol 28, Iss 3, Pp 773-791.e7 (2019)
Summary: Exquisite regulation of energy homeostasis protects from nutrient deprivation but causes metabolic dysfunction upon nutrient excess. In human and murine adipose tissue, the accumulation of ligands of the receptor for advanced glycation end p
Externí odkaz:
https://doaj.org/article/9cda9d74ebcc4ce59e138adbf8231d62
Autor:
Jae Hoon Jeong, Dong Kun Lee, Clemence Blouet, Henry H. Ruiz, Christoph Buettner, Streamson Chua, Jr., Gary J. Schwartz, Young-Hwan Jo
Publikováno v:
Molecular Metabolism, Vol 4, Iss 6, Pp 483-492 (2015)
Objective: Brown adipose tissue (BAT) thermogenesis is critical in maintaining body temperature. The dorsomedial hypothalamus (DMH) integrates cutaneous thermosensory signals and regulates adaptive thermogenesis. Here, we study the function and synap
Externí odkaz:
https://doaj.org/article/17d1ab3d576446ffb2680a5dec743953
Autor:
Robin A. Wilson, Lakshmi Arivazhagan, Henry H. Ruiz, Boyan Zhou, Kun Qian, Michaele B. Manigrasso, Rollanda Bernadin, Kaamashri Mangar, Alexander Shekhtman, Huilin Li, Ravichandran Ramasamy, Ann Marie Schmidt
Publikováno v:
Obesity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::690c8226f07fc2027a66bff731fa497c
https://doi.org/10.1002/oby.23774
https://doi.org/10.1002/oby.23774
Autor:
Lakshmi Arivazhagan, Collin J Popp, Henry H Ruiz, Robin A Wilson, Michaele B Manigrasso, Alexander Shekhtman, Ravichandran Ramasamy, Mary Ann Sevick, Ann Marie Schmidt
Publikováno v:
Cardiovascular research.
Overweight and obesity are leading causes of cardiometabolic dysfunction. Despite extensive investigation, the mechanisms mediating the increase in these conditions are yet to be fully understood. Beyond the endogenous formation of advanced glycation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1c3f1318a4d6f32132a77e1aae74a4
https://pubmed.ncbi.nlm.nih.gov/36448548
https://pubmed.ncbi.nlm.nih.gov/36448548
Autor:
Henry H Ruiz, Ann Marie Schmidt
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
The underlying pathophysiological mechanisms of obesity, a hallmark of metabolic and cardiovascular diseases, are not fully elucidated. Adipocyte hypertrophy contributes to insulin resistance, and is coupled to meaningful alterations in actin dynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fca2fdfd5857e5ea942f2c5881f891c
https://doi.org/10.1161/atvb.41.suppl_1.mp32
https://doi.org/10.1161/atvb.41.suppl_1.mp32
Autor:
Michaele B. Manigrasso, Michael MacLean, Carolina Vasquez, Robin A. Wilson, Ravichandran Ramasamy, Paul F. Gugger, Lakshmi Arivazhagan, Raquel López-Díez, Lander Egaña-Gorroño, Laura M Senatus, Ann Marie Schmidt, Alexander Shekhtman, Henry H. Ruiz
Publikováno v:
Immunometabolism
Fundamental modulation of energy metabolism in immune cells is increasingly being recognized for the ability to impart important changes in cellular properties. In homeostasis, cells of the innate immune system, such as monocytes, macrophages and den
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598609bf6c6e1cd067143582f8f79bb5
https://doi.org/10.20900/immunometab20210024
https://doi.org/10.20900/immunometab20210024
Autor:
Julia Derk, Richard A. Friedman, Carmen Hurtado del Pozo, Meilun He, Ravichandran Ramasamy, Laura Frye, Ann Marie Schmidt, Juan F. Aranda, Hye Lim Noh, Peter Daya, Lakshmi Arivazhagan, Randall H. Friedline, Michael MacLean, Cynthia Shim, Henry H. Ruiz, Jason K. Kim
Publikováno v:
Cell Reports, Vol 28, Iss 3, Pp 773-791.e7 (2019)
Cell reports
Cell reports
SUMMARY Exquisite regulation of energy homeostasis protects from nutrient deprivation but causes metabolic dysfunction upon nutrient excess. In human and murine adipose tissue, the accumulation of ligands of the receptor for advanced glycation end pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd343d60b26e6acbdbf2d38f0bcb5dca
http://www.sciencedirect.com/science/article/pii/S2211124719308344
http://www.sciencedirect.com/science/article/pii/S2211124719308344
Autor:
Julia Derk, Judyta K. Juranek, Ravichandran Ramasamy, Michael MacLean, Ann Marie Schmidt, Henry H. Ruiz
Publikováno v:
Neurochemistry International. 126:154-164
The Receptor for Advanced Glycation End Products (RAGE) is expressed by multiple cell types in the brain and spinal cord that are linked to the pathogenesis of neurovascular and neurodegenerative disorders, including neurons, glia (microglia and astr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb214ab4f01e7392ff35b8d760c5f1b6
https://doi.org/10.1016/j.neuint.2019.03.012
https://doi.org/10.1016/j.neuint.2019.03.012