Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Henry H. Lee"'
Autor:
Anthony P. West, Joel O. Wertheim, Jade C. Wang, Tetyana I. Vasylyeva, Jennifer L. Havens, Moinuddin A. Chowdhury, Edimarlyn Gonzalez, Courtney E. Fang, Steve S. Di Lonardo, Scott Hughes, Jennifer L. Rakeman, Henry H. Lee, Christopher O. Barnes, Priyanthi N. P. Gnanapragasam, Zhi Yang, Christian Gaebler, Marina Caskey, Michel C. Nussenzweig, Jennifer R. Keeffe, Pamela J. Bjorkman
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
West and colleagues develop the Variant Database software tool for examination of changing Spike mutations in SARS-CoV-2 genomes. The authors use this to detect emerging lineages of SARS-CoV-2 in New York and report the rapid spread of the B.1.526 li
Externí odkaz:
https://doaj.org/article/6617c4ad1147439fafe26eec5e36b019
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Adoption of DNA as a data storage medium could be accelerated with specialized synthesis processes and codecs. The authors describe TdT-mediated DNA synthesis in which data is stored in transitions between non-identical nucleotides and the use of syn
Externí odkaz:
https://doaj.org/article/dbba1ab593104571a6b337fe731ad32e
Autor:
Charlie Gilbert, Stephanie L. Brumwell, Alexander Crits-Christoph, Shinyoung Clair Kang, Zaira Martin-Moldes, Wajd Alsharif, Ariela Esmurria, Mary-Anne Nguyen, Henry H. Lee, Nili Ostrov
Microbial genetic manipulation requires access to engineerable plasmids that can be programmed to perturb genes, pathways and genomes. The extensive repertoire of plasmids available for model microbes, such asEscherichia coli, has facilitated fundame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::881202f01687c83e699a8162c128a708
https://doi.org/10.1101/2023.05.19.541510
https://doi.org/10.1101/2023.05.19.541510
Autor:
Zhi Ping, Shihong Chen, Guangyu Zhou, Xiaoluo Huang, Sha Joe Zhu, Haoling Zhang, Henry H. Lee, Zhaojun Lan, Jie Cui, Tai Chen, Wenwei Zhang, Huanming Yang, Xun Xu, George M. Church, Yue Shen
Publikováno v:
Nature Computational Science. 2:234-242
DNA is a promising data storage medium due to its remarkable durability and space-efficient storage. Early bit-to-base transcoding schemes have primarily pursued information density, at the expense of introducing biocompatibility challenges or decodi
Autor:
Michael J. Hammerling, Shinyoung Clair Kang, William Ward, Isabel F. Escapa, Pradeep Bugga, Cybill Del Castillo, Melissa Hopkins, Steven Chase, Sol Rey, Dylan Law, Alexander Carpio, Katharine Nelson, Simran Chhabria, Simran Gupta, Tiara Rivera, Jon M. Laurent, Haiping Hao, Henry H. Lee
In the ongoing COVID-19 pandemic, detecting the appearance and spread of variants of concern (VOC) is a critical capability in the fight to quell the virus and return to normalcy. Genomic surveillance of the emergence, propagation, and geographical s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa6ff8931dfde478112c463191e4b82b
https://doi.org/10.1101/2022.05.25.22273991
https://doi.org/10.1101/2022.05.25.22273991
Autor:
Dylan Law, Erica M. Briggs, Paolo Mita, Katharine K. Nelson, William Ward, Sol Rey, Michael Bois, Henry H. Lee, Nili Ostrov, Jon M Laurent
Publikováno v:
Proc Natl Acad Sci U S A
Severe acute respiratory coronavirus 2 (SARS-CoV-2) pandemic presents new scientific and scale-up challenges for diagnostic capabilities worldwide. The gold standard diagnostic for SARS-CoV-2 infection is an RT-qPCR which targets the SARS-CoV-2 genom
Autor:
Jennifer R. Keeffe, Steve Di Lonardo, Edimarlyn Gonzalez, Michel C. Nussenzweig, Tetyana I Vasylyeva, Courtney E Fang, Priyanthi N. P. Gnanapragasam, Jade C Wang, Jennifer L. Rakeman, Jennifer L Havens, Christian Gaebler, Christopher O. Barnes, Pamela J. Bjorkman, Anthony P. West, Marina Caskey, Zhi Yang, Moinuddin A Chowdhury, Henry H. Lee, Joel O. Wertheim, Scott Hughes
Publikováno v:
Nature communications, vol 12, iss 1
bioRxiv
article-version (status) pre
article-version (number) 3
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
bioRxiv
article-version (status) pre
article-version (number) 3
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Wide-scale SARS-CoV-2 genome sequencing is critical to tracking viral evolution during the ongoing pandemic. We develop the software tool, Variant Database (VDB), for quickly examining the changing landscape of spike mutations. Using VDB, we detect a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::267ce4db24613985c508e174988a4477
https://escholarship.org/uc/item/4g53j9cr
https://escholarship.org/uc/item/4g53j9cr
Autor:
Michael Bois, Paolo Mita, Henry H. Lee, Nili Ostrov, Dylan Law, Jon M Laurent, Kate A Nelson, William Ward, Sol Rey, Erica M. Briggs
The SARS Coronavirus 2 (SARS-CoV-2) pandemic presents new scientific and scale-up challenges for diagnostic capabilities worldwide. The gold standard diagnostic for SARS-CoV-2 infection is a reverse transcription/quantitative PCR (RT-qPCR) which targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a64edd847fea21c5e4f67db1e823f26
https://doi.org/10.1101/2021.06.21.21258023
https://doi.org/10.1101/2021.06.21.21258023
Autor:
Haoling Zhang, Shihong Chen, George M. Church, Zhaojun Lan, Yue Shen, Henry H. Lee, Jie Cui, Huang Xiaoluo, Xun Xu, Tai Chen, Sha Joe Zhu, Zhi Ping, Huanming Yang, Wenwei Zhang, Guangyu Zhou
DNA is a promising data storage medium due to its remarkable durability and space-efficient storage. Early bit-to-base transcoding schemes have primarily pursued information density, at the expense however of introducing biocompatibility challenges o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c391109d2c21f524d1b02b4d7fadd557
https://doi.org/10.21203/rs.3.rs-536997/v1
https://doi.org/10.21203/rs.3.rs-536997/v1
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature Communications
DNA is an emerging medium for digital data and its adoption can be accelerated by synthesis processes specialized for storage applications. Here, we describe a de novo enzymatic synthesis strategy designed for data storage which harnesses the templat