Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Henry G. Wall"'
Publikováno v:
Toxicologic Pathology. 40:391-402
The first electron microscopic images of biological specimens were made in the 1940s, and the next 30 years comprised an era of descriptive ultrastructure during which transmission electron microscopy (TEM) was integral to an explosion in cellular an
Autor:
Ernest E. McConnell, Holly Kolenda-Roberts, Marvin A. Friedman, Robert R. Maronpot, Errol Zeiger, Henry G. Wall
Publikováno v:
Critical Reviews in Toxicology. 39:512-537
To better understand the relevance of tunica vaginalis mesotheliomas (TVM) to human cancer risk, we examined the nature of TVM responses in 21 published rat cancer bioassays against the backdrop of the biology and molecular biology of mesothelium, an
Autor:
Carla E, Torrey, Henry G, Wall, James A, Campbell, Puntipa, Kwanyuen, Debie J, Hoivik, Richard T, Miller, Jane S, Allen, Manuel J, Jayo, Krzysztof, Selinger, Michael J, Santostefano
Publikováno v:
International Journal of Toxicology. 24:327-339
This study was conducted as part of the International Life Sciences Institute (ILSI) Alternatives to Carcinogenicity Testing program and evaluated the carcinogenic potential of clofibrate, a nongenotoxic, peroxisome proliferator-activated receptor (P
Autor:
Ruth M. Lightfoot, Henry G. Wall, Christopher W. Crumbley, Lisa D. Gates, Robert S. Geske, Lawrence W. Yoon, Chandikumar S. Elangbam, Donald Creech
Publikováno v:
Journal of Histochemistry & Cytochemistry. 53:671-677
5-Hydroxytryptamine-2B receptor (5HT2BR) stimulation is known to cause fibroblast mitogenesis, and the mitogenic effect has been proposed to trigger valvular heart disease in humans. In this study, we used real-time polymerase chain reaction (TaqMan)
Publikováno v:
Toxicologic Pathology. 30:483-491
A full assessment of all heart valves in rats and mice is often impractical and is usually not performed in routine toxicity studies, largely due to an inevitable inconsistency of histological sampling. The majority of reported heart valve changes in
Autor:
Heather Conway, Henry G Wall, Jacob D. McDonald, Matthew D. Reed, Ronald K. Wolff, Kelly J. Dix, Rodney A. Miller
Publikováno v:
Inhalation toxicology. 25(13)
Nebulized gentamicin solution was administered to rats (nose-only) and dogs (face mask) for 14 days with a 14-day recovery period. Control groups of each were exposed to saline aerosols. Mean estimated inhaled lung doses of gentamicin were 39, 123 an
Publikováno v:
International journal of toxicology. 31(6)
Male F344 rats were exposed to hydrazobenzene (HZB) by dietary feed at concentrations of 0, 5, 20, 80, 200, or 300 ppm for 5 days, 2 weeks, 4 weeks, or 13 weeks duration. End points evaluated included clinical observations, body weights, liver weight
Autor:
Carlyle D. Flemming, R.E. Wolfe, Henry G. Wall, Richard E. Whitmire, E.R. Kinkead, Susan K. Bunger
Publikováno v:
Toxicology and Industrial Health. 7:295-307
C8 polychlorotrifluoroethylene (pCTFE) oligomers accumulate preferentially in the liver during long-term oral exposure and appear to be more hepatotoxic than C6 oligomers. A repeated-dose gavage study was initiated to determine the relative contribut
Autor:
Edgar C. Kimmel, Susan K. Bunger, Carlyle D. Flemming, E.R. Kinkead, John H. Grabau, Henry G. Wall
Publikováno v:
Toxicology and Industrial Health. 7:309-318
Chloropentafluorobenzene (CPFB) has been identified as a can didate simulant for nonpersistent chemical warfare agents. Acute toxicity studies have shown that CPFB has limited adverse ef fects on laboratory animals. A 21-day inhalation study of rats
Decreased brain pathology in organophosphate-exposed rhesus monkeys following benzodiazepine therapy
Autor:
John V. Wade, Henry G. Wall, James B. Nold, Nancy K. Jaax, Denver D. Marlow, Isaac J. Hayward
Publikováno v:
Journal of the Neurological Sciences. 98:99-106
Two benzodiazepine compounds, midazolam and diazepam, were administered as adjunctive treatment to soman-exposed rhesus monkeys to evaluate their effects on acute soman intoxication. Monkeys were pretreated orally with pyridostigmine, exposed to soma