Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Henry G Smith"'
Autor:
Henry G Smith, Kunzah Jamal, Jasbani HS Dayal, Tencho Tenev, Joan Kyula‐Currie, Naomi Guppy, Patrycja Gazinska, Victoria Roulstone, Gianmaria Liccardi, Emma Davies, Ioannis Roxanis, Alan A Melcher, Andrew J Hayes, Gareth J Inman, Kevin J Harrington, Pascal Meier
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 6, Pp 1-17 (2020)
Abstract Drugs that mobilise the immune system against cancer are dramatically improving care for many people. Dying cancer cells play an active role in inducing anti‐tumour immunity but not every form of death can elicit an immune response. Moreov
Externí odkaz:
https://doaj.org/article/ebe09b78de1144a5ac46382d903dbfad
Autor:
Martin McLaughlin, Malin Pedersen, Victoria Roulstone, Katharina F. Bergerhoff, Henry G. Smith, Harriet Whittock, Joan N. Kyula, Magnus T. Dillon, Hardev S. Pandha, Richard Vile, Alan A. Melcher, Kevin J. Harrington
Publikováno v:
Molecular Therapy: Oncolytics, Vol 16, Iss , Pp 238-249 (2020)
Reovirus type 3 Dearing (reovirus) is a tumor-selective oncolytic virus currently under evaluation in clinical trials. Here, we report that the therapeutic efficacy of reovirus in head and neck squamous cell cancer can be enhanced by targeting the un
Externí odkaz:
https://doaj.org/article/ea1817def2d74912aacb316306d0be16
Autor:
Dario Callegaro, Rosalba Miceli, Sylvie Bonvalot, Peter C. Ferguson, Dirk C. Strauss, Veroniek V.M. van Praag, Antonin Levy, Anthony M. Griffin, Andrew J. Hayes, Silvia Stacchiotti, Cecile Le Pèchoux, Myles J. Smith, Marco Fiore, Angelo Paolo Dei Tos, Henry G. Smith, Charles Catton, Joanna Szkandera, Andreas Leithner, Michiel A.J. van de Sande, Paolo G. Casali, Jay S. Wunder, Alessandro Gronchi
Publikováno v:
EClinicalMedicine, Vol 17, Iss , Pp - (2019)
Background: Prognostic nomograms for patients with extremity soft tissue sarcoma (eSTS) typically predict survival or the occurrence of local recurrence or distant metastasis at time of surgery. Our aim was to develop and externally validate a dynami
Externí odkaz:
https://doaj.org/article/f0b27f46d3334d46bad3c29b1088875e
Publikováno v:
Annals of Surgery. 277:127-135
To investigate whether there is differential impact of histopathological risk factors for lymph node metastases (LNM) in pedunculated and non-pedunculated pT1 colorectal cancers (CRC).Tumour budding, lymphovascular invasion (LVI) and venous invasion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a655ac40ba80916135ff65b28375c9
https://doi.org/10.1097/sla.0000000000005684
https://doi.org/10.1097/sla.0000000000005684
Autor:
Kevin J. Harrington, Martin McLaughlin, Alan Melcher, Anguraj Sadanandam, Anna C. Wilkins, Krisha Desai, Elisa Fontana, Chanthirika Ragulan, Galabina Bozhanova, Shane Foo, Radhika R. Patel, James T.E. Paget, Henry G. Smith, Alex Pearson, Emmanuel C. Patin, Eva Crespo-Rodriguez, Harriet Whittock, Malin Pedersen, Katharina F. Bergerhoff, Magnus T. Dillon
Purpose:ATR inhibitors (ATRi) are in early phase clinical trials and have been shown to sensitize to chemotherapy and radiotherapy preclinically. Limited data have been published about the effect of these drugs on the tumor microenvironment.Experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4954af3c614c3181d2ace55e502316ce
https://doi.org/10.1158/1078-0432.c.6527228.v1
https://doi.org/10.1158/1078-0432.c.6527228.v1
Autor:
Kevin J. Harrington, Martin McLaughlin, Alan Melcher, Anguraj Sadanandam, Anna C. Wilkins, Krisha Desai, Elisa Fontana, Chanthirika Ragulan, Galabina Bozhanova, Shane Foo, Radhika R. Patel, James T.E. Paget, Henry G. Smith, Alex Pearson, Emmanuel C. Patin, Eva Crespo-Rodriguez, Harriet Whittock, Malin Pedersen, Katharina F. Bergerhoff, Magnus T. Dillon
Supplementary figures and tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e78d734f34504452c9609a08573d068
https://doi.org/10.1158/1078-0432.22469357
https://doi.org/10.1158/1078-0432.22469357
Autor:
Andrew J. Hayes, Kevin J. Harrington, Khin Thway, Alan Melcher, Aadil Khan, Magnus T. Dillon, James T. Paget, Katharina F. Bergerhoff, Radhika R. Patel, Martin McLaughlin, Joan N. Kyula-Currie, Victoria Roulstone, David Mansfield, Henry G. Smith
Purpose:The prevention and treatment of metastatic sarcoma are areas of significant unmet need. Immune checkpoint inhibitor monotherapy has shown little activity in sarcoma and there is great interest in identifying novel treatment combinations that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a346e3b40675453b78bd87196e92d1ba
https://doi.org/10.1158/1078-0432.c.6528191.v1
https://doi.org/10.1158/1078-0432.c.6528191.v1
Autor:
Andrew J. Hayes, Kevin J. Harrington, Khin Thway, Alan Melcher, Aadil Khan, Magnus T. Dillon, James T. Paget, Katharina F. Bergerhoff, Radhika R. Patel, Martin McLaughlin, Joan N. Kyula-Currie, Victoria Roulstone, David Mansfield, Henry G. Smith
Supplementary tables and figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542cb332a1bc5ef6846ca968def963b1
https://doi.org/10.1158/1078-0432.22472303.v1
https://doi.org/10.1158/1078-0432.22472303.v1
Autor:
Henry G Smith, Nis H Schlesinger, Dara Lundon, Almog Ben-Yaacov, Carmela Caballero, Wim Ceelen, Ina Suppan, Johnn Herrera Kok, Carl Holmberg, Laura Lorenzon, Helen Mohan, Giacomo Montagna, Nada Santrac, Raza Sayyed, Yvonne Schrage, Olivia Sgarbura, Mariela Vasileva-Slaveva, Andreas Brandl
Publikováno v:
Journal of Cancer Policy. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::985fa5227d6ff3414e2fddf7c7d3aa1d
https://doi.org/10.1016/j.jcpo.2023.100399
https://doi.org/10.1016/j.jcpo.2023.100399
Publikováno v:
British Journal of Surgery. 108:769-776
Background National screening programmes increase the proportion of T1 colorectal cancers. Local excision may be possible, but the risk of lymph node metastases (LNMs) could jeopardize long-term outcomes. The aim of the present study was to review th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0b59790b90cb297c19be7334cf1a35
https://doi.org/10.1093/bjs/znab168
https://doi.org/10.1093/bjs/znab168