Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Henry F. Duncan"'
Publikováno v:
Bioactive Materials, Vol 40, Iss , Pp 182-211 (2024)
The drive for minimally invasive endodontic treatment strategies has shifted focus from technically complex and destructive root canal treatments towards more conservative vital pulp treatment. However, novel approaches to maintaining dental pulp vit
Externí odkaz:
https://doaj.org/article/5a2fd81c53884923b55ce26b02b487cc
Publikováno v:
Bioactive Materials, Vol 27, Iss , Pp 574-593 (2023)
This opinion-led review paper highlights the need for novel translational research in vital-pulp-treatment (VPT), but also discusses the challenges in translating evidence to clinics. Traditional dentistry is expensive, invasive and relies on an outm
Externí odkaz:
https://doaj.org/article/de53515699a04b6185cfa10ea86f0b09
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6569 (2024)
Epigenetic modulation, including histone modification, alters gene expression and controls cell fate. Histone deacetylases (HDACs) are identified as important regulators of dental pulp cell (DPC) mineralisation processes. Currently, there is a paucit
Externí odkaz:
https://doaj.org/article/86b2029274084a7bb9e8a3ab6e2b21e0
Publikováno v:
Methods and Protocols, Vol 7, Iss 2, p 22 (2024)
The dental pulp has critical functions in tooth development as well as an ongoing role in promoting and maintaining the vitality of teeth. In particular, its regenerative ability allows dental tissues to be restored following damage caused by traumat
Externí odkaz:
https://doaj.org/article/c1b19dc321f0461c9f744b6b38538c2d
Autor:
Erika Cadoni, Francesca Ideo, Giuseppe Marongiu, Silvia Mezzena, Luca Frigau, Quirico Mela, Antonio Capone, Henry F. Duncan, Elisabetta Cotti
Publikováno v:
Clinical and Experimental Dental Research, Vol 8, Iss 5, Pp 1068-1075 (2022)
Abstract Objectives To assess the periapical status in patients with osteoporosis (OP) treated with denosumab (D), bisphosphonates (BPs), or not on medication, and to understand if these conditions influence the prevalence and the progression of apic
Externí odkaz:
https://doaj.org/article/051a4c3c63d845efa44bda60ff9fc525
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 875 (2024)
MMP13 gene expression increases up to 2000-fold in mineralizing dental pulp cells (DPCs), with research previously demonstrating that global MMP13 deletion resulted in critical alterations in the dentine phenotype, affecting dentine–tubule regulari
Externí odkaz:
https://doaj.org/article/4585d0a519fe4623a04b4865f36c24dc
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8631 (2023)
Within regenerative endodontics, exciting opportunities exist for the development of next-generation targeted biomaterials that harness epigenetic machinery, including microRNAs (miRNAs), histone acetylation, and DNA methylation, which are used to co
Externí odkaz:
https://doaj.org/article/588abb9402a8412383b53ce2a13d9c0f
Autor:
Henry F. Duncan, Yoshifumi Kobayashi, Yukako Yamauchi, Angela Quispe-Salcedo, Zhi Chao Feng, Jia Huang, Nicola C. Partridge, Teruyo Nakatani, Jeanine D’Armiento, Emi Shimizu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Matrix-metalloproteinase-13 (MMP13) is important for bone formation and remodeling; however, its role in tooth development remains unknown. To investigate this, MMP13-knockout (Mmp13−/−) mice were used to analyze phenotypic changes in the dentin
Externí odkaz:
https://doaj.org/article/f610c1a73e784a919257b58fbbb15662
Autor:
Ikhlas A. El karim, Henry F. Duncan
Publikováno v:
Frontiers in Dental Medicine, Vol 2 (2021)
Over the last 12 months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) virus has emerged as a significant global health problem with extensive repercussions for the practise of dentistry. As the principle transmission-route is via
Externí odkaz:
https://doaj.org/article/854827af8f9842e6a1ba60be84335572
Autor:
Ikhlas A. El karim, Paul R. Cooper, Imad About, Phillip L. Tomson, Fionnuala T. Lundy, Henry F. Duncan
Publikováno v:
Frontiers in Dental Medicine, Vol 2 (2021)
Research over several decades has increased our understanding of the nature of reparative and regenerative processes in the dental pulp, at both the cellular and molecular level. However, advances in scientific knowledge have not translated into nove
Externí odkaz:
https://doaj.org/article/922854437b8a4378a8d78102f1a57120