Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Henry F. Bolte"'
Autor:
Henry F. Bolte, Mark R. Berardi, Barbara Hartman, William Halliwell, Carol S. Auletta, Frederique M. Poulet
Publikováno v:
Toxicologic Pathology. 32:558-566
Phentolamine is a reversible competitive α-adrenergic antagonist with similar affinities for α1 and α2 receptors. It has a long history of safe clinical use, and was developed as a potential therapy for male erectile dysfunction because of its cap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90f5bf3cd7ad5e383b25eb30f3f541d
https://doi.org/10.1080/01926230490505086
https://doi.org/10.1080/01926230490505086
Autor:
Roger W. Reinhold, Gary M. Hoffman, Henry F. Bolte, William E. Rinehart, George M. Rusch, Ralph J. Parod, Martin Kayser
Publikováno v:
Toxicological Sciences. 44:197-205
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eb430be59a1cd82cd7a00dff0f9947c
https://doi.org/10.1093/toxsci/44.2.197
https://doi.org/10.1093/toxsci/44.2.197
Autor:
Brian D. Pillsbury, James B. Terrill, Lionel F. Rubin, Roger Ben-Dyke, Paul E. Newton, Arthur W. Sheldon, Robert T. Drew, Ira W. Daly, Henry F. Bolte
Publikováno v:
Toxicological Sciences. 22:561-576
Fischer 344 rats were exposed by inhalation to Sb2O3 (antimony trioxide) dust at exposure levels of 0, 0.25, 1.08, 4.92, and 23.46 mg/m3 for 6 hr/day, 5 days/week for 13 weeks followed by a 27-week observation period. Subsequently, an inhalation onco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55e35a0fbb9fe07d9b4f5af7d8f1d69
https://doi.org/10.1093/toxsci/22.4.561
https://doi.org/10.1093/toxsci/22.4.561
Publikováno v:
Fundamental and Applied Toxicology. 19:79-90
Male and female Fischer 344 rats (80/sex/group) were exposed to CSM fiber 6 hr/day, 5 days/week at target-exposure levels of 0, 1, 5, or 25 mg/m3 for 24 months, corresponding to 0, 27, 80, and 513 fibers/cc, respectively. Number and size of the airbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75a075ec4e2d57eab192c60b438a36ba
https://doi.org/10.1016/0272-0590(92)90031-c
https://doi.org/10.1016/0272-0590(92)90031-c
Autor:
John E. Dillberger, Aida M. Cancel, David C. Sokal, Dianne M. Creasy, Catherine M. Kelly, Henry F. Bolte
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 56(2)
This study investigated if quinacrine can induce a tumorigenic response in rats when administered in a manner similar to the intended human use for female non-surgical sterilization. Young sexually mature female rats received two doses of quinacrine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240689eb89fcf2cef43c6243d2355505
https://pubmed.ncbi.nlm.nih.gov/20043971
https://pubmed.ncbi.nlm.nih.gov/20043971
Publikováno v:
Inhalation toxicology. 14(12)
Methylethylketoxime, also known as MEKO or 2-butanone oxime (CAS No. 96-29-7), is a clear, colorless to light yellow liquid at room temperature. It is an industrial antioxidant used as an antiskinning agent in alkyd paint, an industrial blocking agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960f40d6b103452d8dd7ee00dae89ba6
https://pubmed.ncbi.nlm.nih.gov/12454789
https://pubmed.ncbi.nlm.nih.gov/12454789
Autor:
Jerry F. Hardisty, Paul E. Newton, Michael J. Derelanko, Henry F. Bolte, William E. Rinehart, William L. Wooding
Publikováno v:
Inhalation toxicology. 13(12)
To evaluate the oncogenic potential of methylethylketoxime (MEKO), CD-1 mice (50/sex/group) and F-344 rats (50/sex/group) were coexposed 6 h/day, 5 days/wk for 18 mo (mice) or 26 mo (rats) via whole-body inhalation exposures to target vapor concentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::314863753e1e49115c7f385db389f05d
https://pubmed.ncbi.nlm.nih.gov/11696876
https://pubmed.ncbi.nlm.nih.gov/11696876
Publikováno v:
Toxicology. 120(2)
The toxicity of ISIS 2302, a phosphorothioate oligonucleotide with antisense activity against human ICAM-1 mRNA, was investigated in cynomolgus monkeys (young adult). The oligonucleotide was administered by slow bolus injection every other day for 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c536fa83acbfc5114224b43f0311ea52
https://pubmed.ncbi.nlm.nih.gov/9184201
https://pubmed.ncbi.nlm.nih.gov/9184201
Publikováno v:
Journal of applied toxicology : JAT. 14(2)
Exposure to anticholinesterase pesticides has been associated with the development of ocular toxicity in humans and animals, ranging from blurred vision to degeneration of the optic nerve. Based on the concern for human safety, the US Environmental P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac44e239e845c512199798e4dbe33e2e
https://pubmed.ncbi.nlm.nih.gov/8027510
https://pubmed.ncbi.nlm.nih.gov/8027510
Publikováno v:
Journal of Toxicology and Environmental Health. 20:117-124
The subchronic inhalation toxicity of methanol was evaluated in rats and monkeys. Animals were exposed to 0, 500, 2000, and 5000 ppm methanol vapor for 6 h/d, 5 d/w, for 4 wk. The only treatment‐ and dose‐related effect noted was that of mucoid n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87358d3021f1be624ce220c06778806a
https://doi.org/10.1080/15287398709530965
https://doi.org/10.1080/15287398709530965