Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Henry F, VanBrocklin"'
Autor:
Jelena Levi, Caroline Guglielmetti, Timothy J. Henrich, John C. Yoon, Prafulla C. Gokhale, David A. Reardon, Juliet Packiasamy, Lyna Huynh, Hilda Cabrera, Marisa Ruzevich, Joseph Blecha, Michael J. Peluso, Tony L. Huynh, Sung-Min An, Mark Dornan, Anthony P. Belanger, Quang-Dé Nguyen, Youngho Seo, Hong Song, Myriam M. Chaumeil, Henry F. VanBrocklin, Hee-Don Chae
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Brown and brown-like adipose tissues have attracted significant attention for their role in metabolism and therapeutic potential in diabetes and obesity. Despite compelling evidence of an interplay between adipocytes and lymphocytes, the inv
Externí odkaz:
https://doaj.org/article/c7333532b2a4485eb5562ae7a4f52c49
Autor:
Jinkyu Jung, Eric L. Schneider, Wei Zhang, Hua Song, Meili Zhang, William Chou, Niranjan Meher, Henry F. VanBrocklin, Mary Helen Barcellos-Hoff, Tomoko Ozawa, Mark R. Gilbert, Daniel V. Santi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Central nervous system tumors have resisted effective chemotherapy because most therapeutics do not penetrate the blood-tumor-brain-barrier. Nanomedicines between ~ 10 and 100 nm accumulate in many solid tumors by the enhanced permeability a
Externí odkaz:
https://doaj.org/article/3d5e6d583d9c4105b0310e06048dd4f3
Autor:
Sally Ji Who Kim, Janine M. Lupo, Yicheng Chen, Miguel H. Pampaloni, Henry F. VanBrocklin, Jared Narvid, Helen Kim, Youngho Seo
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
AimNeuroinflammation plays a key role in both the pathogenesis and the progression of cerebral cavernous malformations (CCM). Flutriciclamide ([18F]GE-180) is a translocator protein (TSPO) targeting positron emission tomography (PET) tracer, develope
Externí odkaz:
https://doaj.org/article/ad99c6ece5384c7aadbe0d17125968d8
Autor:
Denis R. Beckford-Vera, Robert R. Flavell, Youngho Seo, Enrique Martinez-Ortiz, Maya Aslam, Cassandra Thanh, Emily Fehrman, Marion Pardons, Shreya Kumar, Amelia N. Deitchman, Vahid Ravanfar, Brailee Schulte, I-Wei Katherine Wu, Tony Pan, Jacqueline D. Reeves, Christopher C. Nixon, Nikita S. Iyer, Leonel Torres, Sadie E. Munter, Tony Hyunh, Christos J. Petropoulos, Rebecca Hoh, Benjamin L. Franc, Lucio Gama, Richard A. Koup, John R. Mascola, Nicolas Chomont, Steven G. Deeks, Henry F. VanBrocklin, Timothy J. Henrich
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Here, the authors apply positron emission tomography (PET) imaging to visualize HIV tissue-wide burden in infected individuals using a radiolabeled broadly neutralizing antibody, 89Zr-VRC01, and show that PET tracer lymph node uptake positively corre
Externí odkaz:
https://doaj.org/article/42a11e0860df4b12b471a443fa8f7ecb
Autor:
Jelena Levi, Heying Duan, Shahriar Yaghoubi, Juliet Packiasamy, Lyna Huynh, Tina Lam, Faiq Shaikh, Deepak Behera, Hong Song, Joseph Blecha, Salma Jivan, Youngho Seo, Henry F. VanBrocklin
Publikováno v:
Molecular Imaging, Vol 2022 (2022)
Purpose. [18F]F-AraG is a radiolabeled nucleoside analog that shows relative specificity for activated T cells. The aim of this study was to investigate the biodistribution of [18F]F-AraG in healthy volunteers and assess the preliminary safety and ra
Externí odkaz:
https://doaj.org/article/f0bbedca78fb42b38cf3884b3981ae2d
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 315 (2023)
Targeted nanotheranostic systems offer significant benefits due to the integration of diagnostic and therapeutic functionality, promoting personalized medicine. In recent years, prostate-specific membrane antigen (PSMA) has emerged as an ideal theran
Externí odkaz:
https://doaj.org/article/0cdb9960c299463c8162ef608b56cbb5
Publikováno v:
Neurobiology of Disease, Vol 133, Iss , Pp - (2020)
There is a unique in vivo interplay involving the mechanism of inactivation of acetylcholinesterase (AChE) by toxic organophosphorus (OP) compounds and the restoration of AChE activity by oxime antidotes. OP compounds form covalent adducts to this cr
Externí odkaz:
https://doaj.org/article/5a1142ea06b04ef6980b861c7b32bf99
Autor:
Niranjan Meher, Gary W. Ashley, Anil P. Bidkar, Suchi Dhrona, Cyril Fong, Shaun D. Fontaine, Denis R. Beckford Vera, David M. Wilson, Youngho Seo, Daniel V. Santi, Henry F. VanBrocklin, Robert R. Flavell
Publikováno v:
ACS applied materials & interfaces, vol 14, iss 45
Tumoral uptake of large-size nanoparticles is mediated by the enhanced permeability and retention (EPR) effect, with variable accumulation and heterogenous tumor tissue penetration depending on the tumor phenotype. The performance of nanocarriers via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbddcc2aae9f973792d37de877848af5
https://doi.org/10.1021/acsami.2c15095
https://doi.org/10.1021/acsami.2c15095
Autor:
Kiel D. Neumann, Javier E. Villanueva-Meyer, Christopher A. Mutch, Robert R. Flavell, Joseph E. Blecha, Tiffany Kwak, Renuka Sriram, Henry F. VanBrocklin, Oren S. Rosenberg, Michael A. Ohliger, David M. Wilson
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Occult bacterial infections represent a worldwide health problem. Differentiating active bacterial infection from sterile inflammation can be difficult using current imaging tools. Present clinically viable methodologies either detect morpho
Externí odkaz:
https://doaj.org/article/98560c85b2d34a00acba4335bac177d2
Autor:
Robert R. Flavell, Bin Liu, Jonathan Chou, Youngho Seo, Henry F. VanBrocklin, Rahul Aggarwal, David M. Wilson, Jiang He, Li Zhang, Ryan Tang, Yang Su, Denis Beckford-Vera, Chandrashekhar Dasari, Suchi Dhrona, Anju Wadhwa, Niranjan Meher, Umama Ali, Robin Peter, Emily A. Egusa, Scott Bidlingmaier, Emily Chan, Kondapa Naidu Bobba, Sinan Wang, Anil P. Bidkar
Figure S11: Antitumor activity of [225Ac]DOTA-YS5 in subcutaneous DU145 tumors in nude mice. Tumor volume, survival analysis, and weight measurements after the injections of [225Ac]DOTA-YS5 in DU145 xenografts (n=6).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088b646bab868db70b2465e494a23059
https://doi.org/10.1158/1078-0432.22820111.v1
https://doi.org/10.1158/1078-0432.22820111.v1
