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Autor:
Mark D. Black, Denis Boulay, Rosy Sher, Guy Griebel, Sukhveen Sahni, Robert E. Featherstone, Franck Slowinski, Sathapana Kongsamut, Vanessa Naimoli, C. Desvignes, Kosley Raymond W, Geoffrey B. Varty, Xavier Vigé, Olivier Bergis, Lisa Potestio, Philippe Pichat, Henry Defex
Publikováno v:
Scientific Reports
Normalization of altered glutamate neurotransmission through activation of the mGluR2 has emerged as a new approach to treat schizophrenia. These studies describe a potent brain penetrant mGluR2 positive allosteric modulator (PAM), SAR218645. The com