Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Henry B. C. Taylor"'
Autor:
Henry B. C. Taylor, Alexander F. Jeans
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Homeostatic synaptic plasticity (HSP) regulates synaptic strength both pre- and postsynaptically to ensure stability and efficient information transfer in neural networks. A number of neurological diseases have been associated with deficits in HSP, p
Externí odkaz:
https://doaj.org/article/dc65afad0e864488b8517568800a9a05
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Non-evoked miniature release of neurotransmitters is increasingly recognized as playing an important role in neural function and is implicated in synaptic plasticity, metaplasticity, and homeostasis. Spontaneous miniature release events (minis) are u
Externí odkaz:
https://doaj.org/article/b9144708b8674a3fadf23f0593816a3a
Autor:
Alexander Jeans, Zahid Padamsey, Helen Collins, Arn M. J. M. van den Maagdenberg, Henry B. C. Taylor, David M. Bannerman, William Foster, Caroline Weglinski, Nigel J. Emptage, William L. Klein
Publikováno v:
SSRN Electronic Journal.
Amyloid-β (Aβ)-dependent dysfunction and eventual loss of glutamatergic synapses is central to Alzheimer’s disease (AD) pathogenesis. However, the underlying mechanisms remain poorly understood, hindering the development of effective therapeutics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71acf0856c36d0f5aff69fed43d991c7
https://doi.org/10.2139/ssrn.3701260
https://doi.org/10.2139/ssrn.3701260
Publikováno v:
Cell Reports
Summary In Alzheimer’s disease, soluble oligomers of the amyloid-β peptide (Aβo) trigger a cascade of events that includes abnormal hyperphosphorylation of the protein tau, which is essential for pathogenesis. However, the mechanistic link betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c68588b5fa5f50436946323dd220a63
https://doi.org/10.1016/j.celrep.2021.109638
https://doi.org/10.1016/j.celrep.2021.109638
Autor:
William J, Foster, Henry B C, Taylor, Zahid, Padamsey, Alexander F, Jeans, Antony, Galione, Nigel J, Emptage
Publikováno v:
Science signaling. 11(558)
Acidic organelles, such as endosomes and lysosomes, store Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0fa5a1c17f1a7babf6388bf87113baa9
https://pubmed.ncbi.nlm.nih.gov/30482848
https://pubmed.ncbi.nlm.nih.gov/30482848