Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Henry A Choy"'
Autor:
Jean-Louis Escary, Henry A. Choy, Karen Reue, Xu-Ping Wang, Lawrence W. Castellani, Christopher K. Glass, Aldons J. Lusis, Michael C. Schotz
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 3, Pp 397-404 (1999)
Foam cells formed from receptor-mediated uptake of lipoprotein cholesterol by macrophages in the arterial intima are critical in the initiation, progression, and stability of atherosclerotic lesions. Macrophages accumulate cholesterol when conditions
Externí odkaz:
https://doaj.org/article/49376936a7764534a7790ec4d72423aa
Autor:
Henry A Choy
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41566 (2012)
Microbial pathogens acquire the immediate imperative to avoid or counteract the formidable defense of innate immunity as soon as they overcome the initial physical barriers of the host. Many have adopted the strategy of directly disrupting the comple
Externí odkaz:
https://doaj.org/article/895b6f60c4e3419ca9050eb241f5e285
Autor:
Mariana L Coutinho, Henry A Choy, Melissa M Kelley, James Matsunaga, Jane T Babbitt, Michael S Lewis, Jose Antonio G Aleixo, David A Haake
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 12, p e1422 (2011)
The leptospiral LigA protein consists of 13 bacterial immunoglobulin-like (Big) domains and is the only purified recombinant subunit vaccine that has been demonstrated to protect against lethal challenge by a clinical isolate of Leptospira interrogan
Externí odkaz:
https://doaj.org/article/60c73835637e47cab265f267a8c5cfab
Autor:
Henry A Choy, Melissa M Kelley, Julio Croda, James Matsunaga, Jane T Babbitt, Albert I Ko, Mathieu Picardeau, David A Haake
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16879 (2011)
Leptospirosis is a potentially fatal zoonotic disease in humans and animals caused by pathogenic spirochetes, such as Leptospira interrogans. The mode of transmission is commonly limited to the exposure of mucous membrane or damaged skin to water con
Externí odkaz:
https://doaj.org/article/908e1404bdc04d0cb14fc0efa9c36fce
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 9, p e815 (2010)
Pathogenic Leptospira spp. shed in the urine of reservoir hosts into freshwater can be transmitted to a susceptible host through skin abrasions or mucous membranes causing leptospirosis. The infection process involves the ability of leptospires to ad
Externí odkaz:
https://doaj.org/article/a6395a98bc1042a78b8cf2654422ca23
Autor:
Brian Stevenson, Henry A Choy, Marija Pinne, Matthew L Rotondi, M Clarke Miller, Edward Demoll, Peter Kraiczy, Anne E Cooley, Trevor P Creamer, Marc A Suchard, Catherine A Brissette, Ashutosh Verma, David A Haake
Publikováno v:
PLoS ONE, Vol 2, Iss 11, p e1188 (2007)
The pathogenic spirochete Leptospira interrogans disseminates throughout its hosts via the bloodstream, then invades and colonizes a variety of host tissues. Infectious leptospires are resistant to killing by their hosts' alternative pathway of compl
Externí odkaz:
https://doaj.org/article/cf75645695ac434ebc9eb6f2120bffb2
Autor:
Henry A. Choy, Melissa M. Kelley, Tammy L. Chen, Annette K. Møller, David A. Haake, James Matsunaga
Publikováno v:
Infection and Immunity. 75:2441-2450
Transmission of leptospirosis occurs through contact of mucous membranes and abraded skin with freshwater contaminated by pathogenic Leptospira spp. Exposure to physiological osmolarity induces leptospires to express high levels of the Lig surface pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3233597d71e9f243062e2cda6a839315
https://doi.org/10.1128/iai.01635-06
https://doi.org/10.1128/iai.01635-06
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1634:76-85
Macrophage-specific overexpression of cholesteryl ester hydrolysis in hormone-sensitive lipase transgenic (HSL Tg) female mice paradoxically increases cholesterol esterification and cholesteryl ester accumulation in macrophages, and thus susceptibili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509d601a4140f119605459fc18388846
https://doi.org/10.1016/j.bbalip.2003.09.001
https://doi.org/10.1016/j.bbalip.2003.09.001
Publikováno v:
Teratology. 54:34-44
Glucocorticoids (CORT) have been shown to induce cleft palate in mice. Although the pathogenetic pathway of CORT-induced cleft palate has been investigated for several decades, the molecular details remain to be elucidated. Since growth factors have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82a8474213eec75ea1b4b6fea6ff2085
https://doi.org/10.1002/(sici)1096-9926(199607)54:1<34::aid-tera5>3.0.co
https://doi.org/10.1002/(sici)1096-9926(199607)54:1<34::aid-tera5>3.0.co
Publikováno v:
Pediatric Research. 39:749-759
Lung morphogenesis has been shown to be regulated by glucocorticoids (CORT). Because CORT has been primarily thought to affect fetal lung development, previous studies have focused on the role of CORT receptor (GR)-mediated regulation of fetal lung d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ae44bfce83ba466d9020a890900052
https://doi.org/10.1203/00006450-199605000-00002
https://doi.org/10.1203/00006450-199605000-00002