Zobrazeno 1 - 10
of 238
pro vyhledávání: '"Henry, Kim"'
Autor:
Xiaoting Zhou, You-Kyung Lee, Xianting Li, Henry Kim, Carlos Sanchez-Priego, Xian Han, Haiyan Tan, Suiping Zhou, Yingxue Fu, Kerry Purtell, Qian Wang, Gay R. Holstein, Beisha Tang, Junmin Peng, Nan Yang, Zhenyu Yue
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Autophagy is a conserved, catabolic process essential for maintaining cellular homeostasis. Malfunctional autophagy contributes to neurodevelopmental and neurodegenerative diseases. However, the exact role and targets of autophagy in human n
Externí odkaz:
https://doaj.org/article/71903ec458994596b1e2fc44fc246235
Publikováno v:
Western Journal of Emergency Medicine, Vol 24, Iss 6, Pp 1104-1116 (2023)
Introduction: In recent decades, there has been a growing focus on addressing social needs in healthcare settings. California has been at the forefront of making state-level investments to improve care for patients with complex social and medical nee
Externí odkaz:
https://doaj.org/article/608a86ec4b794cd7b04c151122759350
Autor:
Shooshan Danagoulian, Joseph Miller, Bernard Cook, Satheesh Gunaga, Raef Fadel, Chaun Gandolfo, Nicholas L. Mills, Shalini Modi, Simon A. Mahler, Phillip D. Levy, Sachin Parikh, Seth Krupp, Khaled Abdul‐Nour, Howard Klausner, Steven Rockoff, Ryan Gindi, Aaron Lewandowski, Michael Hudson, Giuseppe Perrotta, Bryan Zweig, David Lanfear, Henry Kim, Elizabeth Shaheen, Gale Darnell, Hashem Nassereddine, Kegham Hawatian, Amy Tang, Catriona Keerie, James McCord
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 5, Iss 2, Pp n/a-n/a (2024)
Abstract Objective Protocols to evaluate for myocardial infarction (MI) using high‐sensitivity cardiac troponin (hs‐cTn) have the potential to drive costs upward due to the added sensitivity. We performed an economic evaluation of an accelerated
Externí odkaz:
https://doaj.org/article/39addd9ad218432f8fe3e0f6bc6997bd
Autor:
Henry Kim, Louis Kretz, Céline Ronin, Christina Starck, James A. Roper, Barbro Kahl-Knutson, Kristoffer Peterson, Hakon Leffler, Ulf J. Nilsson, Anders Pedersen, Fredrik R. Zetterberg, Robert J. Slack
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6704 (2024)
The beta-galactoside-binding mammalian lectin galectin-1 can bind, via its carbohydrate recognition domain (CRD), to various cell surface glycoproteins and has been implicated in a range of cancers. As a consequence of binding to sugar residues on ce
Externí odkaz:
https://doaj.org/article/401dc04e96c343c9aa7b54b26cf21dd8
Autor:
Jung Hwa Seo, Jeong Hong Shin, Junwon Lee, Daesik Kim, Hye-Yeon Hwang, Bae-Geun Nam, Jinu Lee, Hyongbum Henry Kim, Sung-Rae Cho
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Huntington’s disease (HD) is caused by a CAG repeat expansion in the huntingtin (HTT) gene. CRISPR-Cas9 nuclease causes double-strand breaks (DSBs) in the targeted DNA that induces toxicity, whereas CRISPR interference (CRISPRi) using dead
Externí odkaz:
https://doaj.org/article/ec1c423e00d74e488b61cd13642bddcb
Autor:
Myungjae Song, Jung Min Lim, Seonwoo Min, Jeong-Seok Oh, Dong Young Kim, Jae-Sung Woo, Hiroshi Nishimasu, Sung-Rae Cho, Sungroh Yoon, Hyongbum Henry Kim
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
While prime editing is a promising technology, PE2 systems often have low efficiency. Here the authors fuse a Rad51 DNA-binding domain to create hyPE2 with improved editing efficiency.
Externí odkaz:
https://doaj.org/article/585d27be31a74bf5926e523fa4034081
Akademický článek
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Autor:
Eul Sik Jung, Ji Hun Kim, Mi-Yoon Chang, Wonjun Hong, Zhejiu Quan, Seung Hyun Kim, Seungkwon You, Dae-Sung Kim, Jiho Jang, Sang-Hun Lee, Hyongbum Henry Kim, Hoon Chul Kang
Publikováno v:
Stem Cell Research, Vol 59, Iss , Pp 102664- (2022)
X-linked adrenoleukodystrophy (ALD) caused by the ABCD1 mutation, is the most common inherited peroxisomal disease. Previously, we generated an ALD patient-derived SCHi001-A iPSC model. In this study, we have performed the first genome editing of ALD
Externí odkaz:
https://doaj.org/article/5d11b80c4cb347fb883062844b1ab6e8
Publikováno v:
IEEE Access, Vol 9, Pp 5517-5530 (2021)
Residential energy trading systems (RETS) enable homeowners with distributed energy resources (DERs) to participate in virtualized energy markets that have the potential to reduce the peak demand of residential communities. Blockchains are key enable
Externí odkaz:
https://doaj.org/article/eb3c27377fdb448fae280ca1f6c2000b
Autor:
Jinyoung Kim, Kihyoun Park, Min Jung Kim, Hyejin Lim, Kook Hwan Kim, Sun-Woo Kim, Eun-Seo Lee, Hyongbum (Henry) Kim, Sung Joo Kim, Kyu Yeon Hur, Jae Hyeon Kim, Jin Hee Ahn, Kun-Ho Yoon, Ji-Won Kim, Myung-Shik Lee
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Islet amyloid polypeptide (IAPP) deposition is associated with islet cell loss in diabetes. Here the authors show that a small molecule autophagy enhancer reduces IAPP accumulation in vitro, and also improves glucose tolerance in hIAPP + mice fed hig
Externí odkaz:
https://doaj.org/article/b7f9dbe17f134b678299722702178b09