Zobrazeno 1 - 10
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pro vyhledávání: '"Henry, Kenneth J."'
Akademický článek
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Autor:
Monahan Patrick E, Li Baolin, Hamdouchi Chafiq, Lineswala Jayana, Henry Kenneth J, Miller Richard J, Ren Dongjun, Bhangoo Sonia, Chan David M, Ripsch Matthew S, White Fletcher A
Publikováno v:
Molecular Pain, Vol 3, Iss 1, p 38 (2007)
Abstract Background Animal and clinical studies have revealed that focal peripheral nerve axon demyelination is accompanied by nociceptive pain behavior. C-C and C-X-C chemokines and their receptors have been strongly implicated in demyelinating poly
Externí odkaz:
https://doaj.org/article/47c76c8349134dd7be3ed637773a2eee
Autor:
Badr Saeed, Douglas Kalvin, Patricia Ewing, Jerome Cohen, Saul H. Rosenberg, Henry Kenneth J, James T. Wasicak, Rolf E. Swenson, Sajeev Cherian, Michael J. Mitten, John J. Larsen, Andrew Tasker, Hing L. Sham, Shi-Chung Ng
Publikováno v:
Journal of Medicinal Chemistry. 42:4844-4852
Synthesis of a library of secondary benzylic amines based on the Sebti-Hamilton type peptidomimetic farnesyltransferase (FTase) inhibitor FTI-276 (1) led to the identification of 6 as a potent enzyme inhibitor (IC(50) of 8 nM) which lacked the proble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5780a23e1287809b0de953a41f3c66cb
https://doi.org/10.1021/jm990335v
https://doi.org/10.1021/jm990335v
Autor:
William J. Chiou, Martin Winn, Robert A. Mantei, Bryan K. Sorensen, Andrew Tasker, Thomas W. von Geldern, Gang Liu, Charles W. Hutchins, Boyd Steven A, Jinshyun R. Wu-Wong, Kennan C. Marsh, Douglas B. Dixon, Bach Nguyen, Terry J. Opgenorth, Henry Kenneth J
Publikováno v:
Bioorganic & Medicinal Chemistry. 7:991-1002
Endothelins, ET-1, ET-2, and ET-3 are potent vasoconstricting and mitogenic 21-amino acid bicyclic peptides, which exert their effects upon binding to the ET A and ET B receptors. The ET A receptor mediates vasoconstriction and smooth muscle cell pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774eb920ffc93a25410b5a8ff75a0d43
https://doi.org/10.1016/s0968-0896(99)00022-x
https://doi.org/10.1016/s0968-0896(99)00022-x
Autor:
William J. Chiou, Henry Kenneth J, T. J. Opgenorth, Wu-Wong, Doug Dixon, Steven A. Boyd, Kennan C. Marsh, James T. Wasicak, Bach Nguyen, N. S. Kozmina, M. Winn, Bruce G. Szczepankiewicz, von Geldern Tw, Gang Liu
Publikováno v:
Journal of medicinal chemistry. 41(17)
Previously we have reported the discovery of ABT-627 (1, A-147627, active enantiomer of A-127722), a 2,4-diaryl substituted pyrrolidine-3-carboxylic acid based endothelin receptor-A antagonist. This compound binds to the ETA receptor with an affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a3ca60f6317d0a2288a4afcb64c157
https://pubmed.ncbi.nlm.nih.gov/9703472
https://pubmed.ncbi.nlm.nih.gov/9703472
Publikováno v:
In Tetrahedron Letters 2007 48(10):1791-1794
Akademický článek
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Autor:
Bhangoo, Sonia, Ren, Dongjun, Miller, Richard J., Henry, Kenneth J., Lineswala, Jayana, Hamdouchi, Chafiq, Li, Baolin, Monahan, Patrick E., Chan, David M., Ripsch, Matthew S., White, Fletcher A.
Publikováno v:
Molecular Pain; 2007, Vol. 3 Issue 1, p38-57, 20p
Publikováno v:
Chirality; 2000, Vol. 12 Issue 5/6, p488-495, 8p
Publikováno v:
Chirality; 2000, Vol. 12 Issue: 5-6 p488-495, 8p