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pro vyhledávání: '"Henry, C M"'
Akademický článek
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Autor:
Henry C. M. Leung, Huijing Yu, Yifan Zhang, Wing Sze Leung, Ivan F. M. Lo, Ho Ming Luk, Wai-Chun Law, Ka Kui Ma, Chak Lim Wong, Yat Sing Wong, Ruibang Luo, Tak-Wah Lam
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Structural variation (SV) is a major cause of genetic disorders. In this paper, we show that low-depth (specifically, 4×) whole-genome sequencing using a single Oxford Nanopore MinION flow cell suffices to support sensitive detection of SV,
Externí odkaz:
https://doaj.org/article/f6842310431a4a36b0dd0196e0ce34ff
Designing short DNA words is a problem of constructing a set (i.e., code) of n DNA strings (i.e., words) with the minimum length such that the Hamming distance between each pair of words is at least k and the n words satisfy a set of additional const
Externí odkaz:
http://arxiv.org/abs/1201.6358
Autor:
Leung, Henry C. M.1 (AUTHOR), Yu, Huijing1 (AUTHOR), Zhang, Yifan1 (AUTHOR), Leung, Wing Sze1 (AUTHOR), Lo, Ivan F. M.2 (AUTHOR), Luk, Ho Ming2 (AUTHOR), Law, Wai-Chun3 (AUTHOR), Ma, Ka Kui1 (AUTHOR), Wong, Chak Lim1 (AUTHOR), Wong, Yat Sing1 (AUTHOR), Luo, Ruibang1 (AUTHOR) rbluo@cs.hku.hk, Lam, Tak-Wah1 (AUTHOR) twlam@cs.hku.hk
Publikováno v:
Scientific Reports. 3/16/2022, Vol. 12 Issue 1, p1-8. 8p.
Autor:
Bone S.F. Tang, Yvonne Chung, Chun Hang Au, Dona N. Ho, Tsun Leung Chan, Elaine Yue Ling Wong, Wai Sing Chan, Edmond S. K. Ma, Tak-Wah Lam, Henry C. M. Leung
Publikováno v:
BMC Research Notes, Vol 13, Iss 1, Pp 1-7 (2020)
BMC Research Notes
BMC Research Notes
Objective We designed and tested a Nanopore sequencing panel for direct tuberculosis drug resistance profiling. The panel targeted 10 resistance-associated loci. We assessed the feasibility of amplifying and sequencing these loci from 23 clinical spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a20ac2692db5f7824de8d9c4319f402
http://link.springer.com/article/10.1186/s13104-020-05287-9
http://link.springer.com/article/10.1186/s13104-020-05287-9
Autor:
Henry C. M. Leung, Wai-Sing Chan, Edmond S. K. Ma, Dinghua Li, Chun Hang Au, Dona N. Ho, Tak-Wah Lam, Bone S.F. Tang, T. K. Chan
Publikováno v:
Future Cardiology. 15:411-424
Aim: To explore potential utility of metagenomic sequencing for improving etiologic diagnosis of infective endocarditis (IE) caused by fastidious bacteria. Materials & methods: Plasma and heart valves of two patients, who were diagnosed with IE cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a70c635c5f7969a356d22e379adb19d
https://doi.org/10.2217/fca-2018-0088
https://doi.org/10.2217/fca-2018-0088
Publikováno v:
Zeitschrift für Pflanzenkrankheiten und Pflanzenschutz / Journal of Plant Diseases and Protection, 1999 May 01. 106(3), 275-283.
Externí odkaz:
https://www.jstor.org/stable/43215290
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114253 (2014)
Since the read lengths of high throughput sequencing (HTS) technologies are short, de novo assembly which plays significant roles in many applications remains a great challenge. Most of the state-of-the-art approaches base on de Bruijn graph strategy
Externí odkaz:
https://doaj.org/article/9ae0690a65ad42599be3f01b62fd6379
Autor:
Ruibang Luo, Zheng Z, Alan W. Leung, Lui W, Luk Hm, Tak-Wah Lam, Henry C. M. Leung, Chak-Lim Wong, Lo If
BackgroundThe application of long-read sequencing using the Oxford Nanopore Technologies (ONT) MinION sequencer is getting more diverse in the medical field. Having a high sequencing error of ONT and limited throughput from a single MinION flowcell,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07fa11d88dea0e668390518bba5fde3c
https://doi.org/10.1101/2021.04.05.438455
https://doi.org/10.1101/2021.04.05.438455
Autor:
Yan Xin, Patrick C. Y. Woo, Henry C. M. Leung, Tak-Wah Lam, Ruibang Luo, Wui Wang Lui, Jade L. L. Teng, Amy W. S. Leung
Publikováno v:
BIBM
Accurate and sensitive taxonomic profiling is essential for any metagenomic analysis to reveal microbial community structure and for potential functional prediction. Antimicrobial resistance (AMR) detection is also a critical task in the clinical dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c84e1bc6ab150a32e27f3e5c413c8f15
https://doi.org/10.1109/bibm49941.2020.9313313
https://doi.org/10.1109/bibm49941.2020.9313313