Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Henrique Serezani"'
Autor:
Huajia Zhang, Sonia Rodriguez, Lin Wang, Soujuan Wang, Henrique Serezani, Reuben Kapur, Angelo A. Cardoso, Nadia Carlesso
Publikováno v:
Stem Cell Reports, Vol 6, Iss 6, Pp 940-956 (2016)
Summary: Toll-like receptor 4 (TLR4) plays a central role in host responses to bacterial infection, but the precise mechanism(s) by which its downstream signaling components coordinate the bone marrow response to sepsis is poorly understood. Using mi
Externí odkaz:
https://doaj.org/article/00ef045ab67d47d2902a027e9e1de504
Autor:
Ly Pham, Padmini Komalavilas, Alex M. Eddie, Timothy E. Thayer, Dalton L. Greenwood, Ken H. Liu, Jaclyn Weinberg, Andrew Patterson, Joshua P. Fessel, Kelli L. Boyd, Jenny C. Schafer, Jamie L. Kuck, Aaron C. Shaver, David K. Flaherty, Brittany K. Matlock, Christiaan D. M. Wijers, C. Henrique Serezani, Dean P. Jones, Evan L. Brittain, Jeffrey C. Rathmell, Michael J. Noto
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Cpt1a-dependent fatty acid beta-oxidation is found to regulate neutrophil trafficking to the site of infection in a mouse model of pneumonia and is found to play a role in pneumonia susceptibility in humans.
Externí odkaz:
https://doaj.org/article/d76a7386c54d4c2f854b839fc40b5550
Autor:
Michelle L. Korir, Ryan S. Doster, Jacky Lu, Miriam A. Guevara, Sabrina K. Spicer, Rebecca E. Moore, Jamisha D. Francis, Lisa M. Rogers, Kathryn P. Haley, Amondrea Blackman, Kristen N. Noble, Alison J. Eastman, Janice A. Williams, Steven M. Damo, Kelli L. Boyd, Steven D. Townsend, C. Henrique Serezani, David M. Aronoff, Shannon D. Manning, Jennifer A. Gaddy
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Perinatal infection with Group B Streptococcus (GBS) is associated with preterm birth, neonatal sepsis, and stillbirth. Here, Korir et al. show that gene cadD, encoding a putative metal efflux transporter, is important for metal detoxification, immun
Externí odkaz:
https://doaj.org/article/597dc8cb42f34cfcbcc7b2c564bd3327
Autor:
Neil T. Sprenkle, Nathan C. Winn, Kaitlyn E. Bunn, Yang Zhao, Deborah J. Park, Brenna G. Giese, John J. Karijolich, K. Mark Ansel, C. Henrique Serezani, Alyssa H. Hasty, Heather H. Pua
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112928- (2023)
Summary: Identifying molecular circuits that control adipose tissue macrophage (ATM) function is necessary to understand how ATMs contribute to tissue homeostasis and obesity-induced insulin resistance. In this study, we find that mice with a myeloid
Externí odkaz:
https://doaj.org/article/818abb9941584f42ae9b426fc3080508
Autor:
Cara Lang, Sohini Roy, Yu Wang, Diana Graves, Yaomin Xu, C. Henrique Serezani, Michael Korrer, Young J. Kim
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Caspase-1 signaling in myeloid suppressor cells can promote T-cell independent cancer progression, but the regulation of inflammasome signaling within the highly heterogeneous myeloid population in the tumor milieu remains elusive. To resolve this co
Externí odkaz:
https://doaj.org/article/8afb072ac409417e812c9720a0d5d7ee
Autor:
Pegah Mehrpouya-Bahrami, Alina K. Moriarty, Paulo De Melo, W. Coles Keeter, Nada S. Alakhras, Andrew S. Nelson, Madeline Hoover, Maria S. Barrios, Jerry L. Nadler, C. Henrique Serezani, Mark H. Kaplan, Elena V. Galkina
Publikováno v:
JCI Insight, Vol 6, Iss 14 (2021)
Signal transducer and activator of transcription 4 (STAT4) is expressed in hematopoietic cells and plays a key role in the differentiation of T helper 1 cells. Although STAT4 is required for immunity to intracellular pathogens, the T cell–independe
Externí odkaz:
https://doaj.org/article/b83149859da34de388f9135a72903011
Autor:
Salina, Ana Carolina Guerta, de Aquino Penteado, Letícia, Dejani, Naiara Naiana, Silva-Pereira, Ludmilla, Raimundo, Breno Vilas Boas, Corrêa, Gabriel Ferranti, Oliveira, Karen Cristina, Ramalho, Leandra Naira Zambelli, Boko, Mèdéton Mahoussi Michaël, Bonato, Vânia L. D., Henrique Serezani, C., Medeiros, Alexandra Ivo
Publikováno v:
Apoptosis; Apr2024, Vol. 29 Issue 3/4, p321-330, 10p
Akademický článek
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Autor:
Nathan Klopfenstein, Stephanie L Brandt, Sydney Castellanos, Matthias Gunzer, Amondrea Blackman, C Henrique Serezani
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009387 (2021)
The skin innate immune response to methicillin-resistant Staphylococcus aureus (MRSA) culminates in the formation of an abscess to prevent bacterial spread and tissue damage. Pathogen recognition receptors (PRRs) dictate the balance between microbial
Externí odkaz:
https://doaj.org/article/1779f18dc5e84c0fbac6cebf2508449d
Publikováno v:
The Journal of Immunology. 210:359-368
Macrophages are sentinels of the innate immune system that maintain tissue homeostasis and contribute to inflammatory responses. Their broad scope of action depends on both functional heterogeneity and plasticity. Small noncoding RNAs called microRNA