Lymphatic endothelial cells prime naïve CD8+ T cells into memory cells under steady-state conditions

Autor: Efthymia Vokali, Shann S. Yu, Sachiko Hirosue, Marcela Rinçon-Restrepo, Fernanda V. Duraes, Stefanie Scherer, Patricia Corthésy-Henrioud, Witold W. Kilarski, Anna Mondino, Dietmar Zehn, Stéphanie Hugues, Melody A. Swartz

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)

Lymphatic endothelial cells (LECs) can cross-present antigen to naïve CD8+ T cells, but the significance of this interaction was unclear. Here the authors show that LECs directly induce CD8+ T cell differentiation with memory-like phenotypes, migrat

Externí odkaz: https://doaj.org/article/f23b98b899c044b5baa15c4c746b6da2

Lymphatic endothelial cells prime naïve CD8+ T cells into memory cells under steady-state conditions

Autor: Stefanie Scherer, Melody A. Swartz, Marcela Rincon-Restrepo, Stéphanie Hugues, Efthymia Vokali, Witold W. Kilarski, Sachiko Hirosue, Dietmar Zehn, Anna Mondino, Patricia Corthésy-Henrioud, Fernanda V. Duraes, Shann S. Yu

Publikováno v: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications, Vol. 11, No 1 (2020) P. 538

Lymphatic endothelial cells (LECs) chemoattract naïve T cells and promote their survival in the lymph nodes, and can cross-present antigens to naïve CD8+ T cells to drive their proliferation despite lacking key costimulatory molecules. However, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718400f022630378a2c95e8658dd96e8

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Determination of the Optimal Disassembly Sequence Using Decision Trees

Autor: Duta, L., Filip, F. Gh., Henrioud, J.M.

Publikováno v: In IFAC Proceedings Volumes October 2003 36(23):43-48

Driving immune responses with synthetic proteins - development of de novo designed immunogens to elicit respiratory syncytial virus neutralizing antibodies

Autor: Sesterhenn, Fabian, Yang, Che, Bonet, Jaume, Galloux, Marie, Wen, Xiaolin, Cramer, Johannes Thomas, Henrioud, Patricia Corthesy, Rosset, Stéphane, Eleouet, Jean Francois, Jardetzky, Ted, Krey, Thomas, Riffault, Sabine, Correia, Bruno Emanuel

Publikováno v: Protein Science
32nd Annual Symposium of the Protein-Society
32nd Annual Symposium of the Protein-Society, Protein Society. USA. Beckman Coulter Inc, USA. Pall ForteBio, USA. Bristol-Myers Squibb (BMS), USA., Jul 2018, Boston, United States. pp.2

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::fbebd923d43eee91dd9ce3d0a9ee1b07
https://hal.inrae.fr/hal-02734561