Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Henrike Liptau"'
Autor:
David Hassel, Roland Hetzer, Hugo A. Katus, Peter Nürnberg, Wolfgang Rottbauer, Tillman Dahme, Henrike Liptau, Benjamin Meder, Monika Stoll, Dieter Weichenhan, Christine Fischer, Philipp Ehlermann, Andreas Huge, Vera Regitz-Zagrosek, Matthias Grimmler, Alexander Hess, Jeanette Erdmann, Heribert Schunkert, Steffen Just
Publikováno v:
Nature Medicine. 15:1281-1288
Z-disks, the mechanical integration sites of heart and skeletal muscle cells, link anchorage of myofilaments to force reception and processing. The key molecules that enable the Z-disk to persistently withstand the extreme mechanical forces during mu
Autor:
Stefan Blankenberg, Alistair S. Hall, Ralph McGinnis, Peter S. Braund, Alison H. Goodall, Richard J. Dixon, Nilesh J. Samani, Inke R. König, Daniel F Schwarz, Christian Hengstenberg, Andrew Keniry, John R. Thompson, Jeanette Erdmann, François Cambien, Nour Eddine El Mokhtari, Stefan Schreiber, Massimo Mangino, Panos Deloukas, Willem H. Ouwehand, Klaus Stark, Pierre Ducimetière, Marcus Fischer, Laurence Tiret, Andreas Ziegler, Christa Meisinger, Henrike Liptau, H.-Erich Wichmann, Anika Götz, Helen Pollard, David-Alexandre Trégouët, Mohammed J. R. Ghori, Patrick Linsel-Nitschke, Heribert Schunkert, Ludwig A. Hothorn
Publikováno v:
Circulation. 117:1675-1684
Background— Recently, genome-wide association studies identified variants on chromosome 9p21.3 as affecting the risk of coronary artery disease (CAD). We investigated the association of this locus with CAD in 7 case-control studies and undertook a
Autor:
Jeanette Erdmann, Patrick Linsel-Nitschke, Henrike Liptau, Reinhard Depping, Piotr M. Kaczmarek, Eva-Maria Ehlers, Heribert Schunkert, Zouhair Aherrahrou, Lars C. Doehring
Publikováno v:
Journal of Biological Chemistry. 283:7608-7615
Dystrophic cardiac calcification (DCC) is an autosomal recessive trait characterized by calcium phosphate deposits in myocardial tissue. The Abcc6 gene locus was recently found to mediate DCC; however, at the molecular level the causative variants re
Autor:
Peter W. Radke, Hans-Werner Hense, Henrike Liptau, Björn Mayer, Jeanette Erdmann, Andrea Bässler, Heribert Schunkert, Marcus Fischer, Lars C. Doehring, Anika Götz, Stephan R. Holmer, Zouhair Aherrahrou, Wolfgang Lieb, Christian Hengstenberg
Publikováno v:
Journal of Hypertension. 25:1731-1738
OBJECTIVES Coronary artery calcification (CAC) determined by electron beam computed tomography is a predictor of future cardiovascular events. This study investigates conditions affecting CAC severity in patients with coronary artery disease (CAD) un
Autor:
Eva-Maria Ehlers, Sandra Wrobel, Piotr M. Kaczmarek, Andrea Pomarino, Anika Götz, Jeanette Erdmann, Lars C. Doehring, Heribert Schunkert, Zouhair Aherrahrou, Henrike Liptau, Bjoern Mayer
Publikováno v:
Physiological Genomics. 28:203-212
In mice, dystrophic cardiovascular calcification (DCC) is controlled by a major locus on proximal mouse chromosome 7 named Dyscalc1. Here we present a strategy that combines in silico analysis, expression analysis, and extensive sequencing for ultraf
Autor:
Hans H. Sievers, Heribert Schunkert, Jeanette Erdmann, Sandra Wrobel, Salah A. Mohamed, Carolin Hagemann, Zouhair Aherrahrou, K. Borzym, Henrike Liptau, Armin W. Erasmi
Publikováno v:
Biochemical and biophysical research communications. 345(4)
The bicuspid aortic valve (BAV) is the most common congenital cardiac malformation, occurring in 1-2% of the population. In a recent report, mutations in NOTCH1 a signaling and transcriptional regulator have been shown to cause BAV in two families. T
Autor:
Henrike Liptau, Christoph Viebahn
Publikováno v:
Differentiation; research in biological diversity. 65(4)
A central problem in embryological research is the identification of mechanisms by which control over the development of a viable individual is maintained. An important role in this process is attributed to intercellular communication the preconditio