EGF Activates Autocrine TGFα to Induce Prolonged EGF Receptor Signaling and Hepatocyte Proliferation

Autor: ShuZheng Liu, Lene Wierød, Ellen Skarpen, Helga Grøsvik, GuangCai Duan, Henrik S. Huitfeldt

Publikováno v: Cellular Physiology and Biochemistry, Vol 32, Iss 3, Pp 511-522 (2013)

Background/Aims: EGF receptor is a main participant in the regulation of liver regeneration. In primary hepatocyte cultures, EGF or TGFα binding to EGF receptor activates Erk1/2 and PI3K pathways, induces cyclin D1 and thus initiates DNA synthesis.

Externí odkaz: https://doaj.org/article/42962ef5484846d7ac39f8a3bda88bc7

Miljøgifter i norsk mat

Autor: Bjørn J. Bolann, Henrik S. Huitfeldt

Publikováno v: Tidsskrift for Den norske legeforening.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::66d096a6a6fdb8ac8bf2fd1a0f3d9274
https://doi.org/10.4045/tidsskr.21.0499

Evidence of selective activation of aryl hydrocarbon receptor nongenomic calcium signaling by pyrene

Autor: Isabelle Gallais, Eric Le Ferrec, Bendik Christian Brinchmann, Jørn A. Holme, Henrik S. Huitfeldt, William H. Bisson, Johan Øvrevik, Normand Podechard, Dominique Lagadic-Gossmann, Odile Sergent

Publikováno v: Biochemical Pharmacology
Biochemical Pharmacology, Elsevier, 2018, 158, pp.1-12. ⟨10.1016/j.bcp.2018.09.023⟩
Biochemical Pharmacology, 2018, 158, pp.1-12. ⟨10.1016/j.bcp.2018.09.023⟩

In its classical genomic mode of action, the aryl hydrocarbon receptor (AhR) acts as a ligand activated transcription factor regulating expression of target genes such as CYP1A1 and CYP1B1. Some ligands may also trigger more rapid nongenomic response

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648f96730f87b69358e904f524a13842
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01888873

Are environmental pollutants in the Norwegian diet harmful to children?

Autor: Bjørn J, Bolann, Sandra, Huber, Jerome, Ruzzin, Jan, Brox, Henrik S, Huitfeldt, Anne-Lise Bjørke, Monsen

Publikováno v: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke. 137(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cf85a965b831d1dcb65e277b36df652b
https://pubmed.ncbi.nlm.nih.gov/28225239

EGF Activates Autocrine TGFα to Induce Prolonged EGF Receptor Signaling and Hepatocyte Proliferation

Autor: GuangCai Duan, Helga Grøsvik, Ellen Skarpen, Lene Wierød, ShuZheng Liu, Henrik S. Huitfeldt

Publikováno v: Cellular Physiology and Biochemistry, Vol 32, Iss 3, Pp 511-522 (2013)

Background/Aims: EGF receptor is a main participant in the regulation of liver regeneration. In primary hepatocyte cultures, EGF or TGFα binding to EGF receptor activates Erk1/2 and PI3K pathways, induces cyclin D1 and thus initiates DNA synthesis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaceb9b25fe3b040f4efcbd59845fd73
http://www.karger.com/Article/FullText/354454