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pro vyhledávání: '"Henrik Landerer"'
Autor:
Elena Senís, Lluc Mosteiro, Stefan Wilkening, Ellen Wiedtke, Ali Nowrouzi, Saira Afzal, Raffaele Fronza, Henrik Landerer, Maria Abad, Dominik Niopek, Manfred Schmidt, Manuel Serrano, Dirk Grimm
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
In vivo reprogramming of somatic cells is hampered by the need for vectors to express the OKSM factors in selected organs. Here the authors report new AAV-based vectors capable of in vivo reprogramming at low doses.
Externí odkaz:
https://doaj.org/article/097051282c3e433e8f3bfa8162e92d23
Autor:
Dominik Niopek, Elena Senís, María Abad, Dirk Grimm, Stefan Wilkening, Saira Afzal, Henrik Landerer, Lluc Mosteiro, Ellen Wiedtke, Ali Nowrouzi, Raffaele Fronza, Manuel Serrano, Manfred Schmidt
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Communications
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Communications
In vivo reprogramming of somatic cells into induced pluripotent stem cells (iPSC) holds vast potential for basic research and regenerative medicine. However, it remains hampered by a need for vectors to express reprogramming factors (Oct-3/4, Klf4, S