Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Henrik Jessen Jürgensen"'
Autor:
Daniel Hargbøl Madsen, Henrik Jessen Jürgensen, Majken Storm Siersbæk, Dorota Ewa Kuczek, Loretta Grey Cloud, Shihui Liu, Niels Behrendt, Lars Grøntved, Roberto Weigert, Thomas Henrik Bugge
Publikováno v:
Cell Reports, Vol 21, Iss 13, Pp 3662-3671 (2017)
Physiologic turnover of interstitial collagen is mediated by a sequential pathway in which collagen is fragmented by pericellular collagenases, endocytosed by collagen receptors, and routed to lysosomes for degradation by cathepsins. Here, we use int
Externí odkaz:
https://doaj.org/article/8fc17f701ab7401a80b235b457b46cfd
Autor:
Pınar Çakılkaya, Rikke Raagaard Sørensen, Henrik Jessen Jürgensen, Oliver Krigslund, Henrik Gårdsvoll, Christoffer F. Nielsen, Eric Santoni-Rugiu, Niels Behrendt, Lars H. Engelholm
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11452 (2021)
Malignant mesothelioma (MM) is a highly aggressive cancer with limited therapeutic options. We have previously shown that the endocytic collagen receptor, uPARAP, is upregulated in certain cancers and can be therapeutically targeted. Public RNA expre
Externí odkaz:
https://doaj.org/article/bf9c3787659c42d8b0502307136ed2ba
Autor:
Kirstine Sandal Nørregaard, Henrik Jessen Jürgensen, Henrik Gårdsvoll, Lars Henning Engelholm, Niels Behrendt, Kent Søe
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 6865 (2021)
Cancer-induced bone degradation is part of the pathological process associated with both primary bone cancers, such as osteosarcoma, and bone metastases originating from, e.g., breast, prostate, and colon carcinomas. Typically, this includes a cancer
Externí odkaz:
https://doaj.org/article/69575cd56a2344aa9449a4d0d3eabec5
Autor:
Stine Friis, Daniel Tadeo, Sylvain M. Le-Gall, Henrik Jessen Jürgensen, Katiuchia Uzzun Sales, Eric Camerer, Thomas H. Bugge
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-17 (2017)
Abstract Background Matriptase is a membrane serine protease essential for epithelial development, homeostasis, and regeneration, as well as a central orchestrator of pathogenic pericellular signaling in the context of inflammatory and proliferative
Externí odkaz:
https://doaj.org/article/96b236299cf5401b81b37fb6c67c3c7b