Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Henrik G, Dohlman"'
Autor:
Kevin M. Knight, Brian E. Krumm, Nicholas J. Kapolka, W. Grant Ludlam, Meng Cui, Sepehr Mani, Iya Prytkova, Elizabeth G. Obarow, Tyler J. Lefevre, Wenyuan Wei, Ning Ma, Xi-Ping Huang, Jonathan F. Fay, Nagarajan Vaidehi, Alan V. Smrcka, Paul A. Slesinger, Diomedes E. Logothetis, Kirill A. Martemyanov, Bryan L. Roth, Henrik G. Dohlman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Many neurotransmitter receptors activate G proteins through exchange of GDP for GTP. The intermediate nucleotide-free state has eluded characterization, due largely to its inherent instability. Here we characterize a G protein variant associ
Externí odkaz:
https://doaj.org/article/a1bbb4b8f5a447f79e49586a70a5bd73
Autor:
Kevin M. Knight, Elizabeth G. Obarow, Wenyuan Wei, Sepehr Mani, Maria I. Esteller, Meng Cui, Ning Ma, Sarah A. Martin, Emily Brinson, Natalie Hewitt, Gaby M. Soden, Diomedes E. Logothetis, Nagarajan Vaidehi, Henrik G. Dohlman
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113578- (2023)
Externí odkaz:
https://doaj.org/article/6991d359de2f468da104364bc1e9ffc9
Autor:
Shuang Li, Yuanyuan Li, Blake R Rushing, Sarah E Harris, Susan L McRitchie, Janice C Jones, Daniel Dominguez, Susan J Sumner, Henrik G Dohlman
Publikováno v:
PLoS Genetics, Vol 17, Iss 7, p e1009640 (2021)
Heterotrimeric G proteins were originally discovered through efforts to understand the effects of hormones, such as glucagon and epinephrine, on glucose metabolism. On the other hand, many cellular metabolites, including glucose, serve as ligands for
Externí odkaz:
https://doaj.org/article/b1d6d008d7d84ee7807ee27521839932
Autor:
Shuang Li, Yuanyuan Li, Blake R. Rushing, Sarah E. Harris, Susan L. McRitchie, Daniel Dominguez, Susan J. Sumner, Henrik G. Dohlman
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 175 (2022)
The yeast Saccharomyces cerevisiae has long been used to produce alcohol from glucose and other sugars. While much is known about glucose metabolism, relatively little is known about the receptors and signaling pathways that indicate glucose availabi
Externí odkaz:
https://doaj.org/article/21c75afb0ace4dfcbc7d7e978dfd7343
Autor:
Natalie Hewitt, Ning Ma, Nadia Arang, Sarah A. Martin, Ajit Prakash, Jeffrey F. DiBerto, Kevin M. Knight, Soumadwip Ghosh, Reid H. J. Olsen, Bryan L. Roth, J. Silvio Gutkind, Nagarajan Vaidehi, Sharon L. Campbell, Henrik G. Dohlman
Publikováno v:
Sci Signal
Heterotrimeric guanine nucleotide–binding proteins (G proteins) that function as molecular switches for cellular growth and metabolism are activated by GTP and inactivated by GTP hydrolysis. In uveal melanoma, a conserved glutamine residue critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d826b894becd7f7b7fd4f5b9cd98a9b
https://doi.org/10.1126/scisignal.abq7842
https://doi.org/10.1126/scisignal.abq7842
Autor:
James P Shellhammer, Elizabeth Morin-Kensicki, Jacob P Matson, Guowei Yin, Daniel G Isom, Sharon L Campbell, Robert P Mohney, Henrik G Dohlman
Publikováno v:
PLoS Genetics, Vol 13, Iss 5, p e1006829 (2017)
All cells respond to osmotic stress by implementing molecular signaling events to protect the organism. Failure to properly adapt can lead to pathologies such as hypertension and ischemia-reperfusion injury. Mitogen-activated protein kinases (MAPKs)
Externí odkaz:
https://doaj.org/article/e1557cf21e24484d89a2ddd935501880
Autor:
Shuang Li, Henrik G. Dohlman
Publikováno v:
Journal of Biological Chemistry. 299:104617
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88a4bc5adcc9123c9b7e73b766b909d1
https://doi.org/10.1016/j.jbc.2023.104617
https://doi.org/10.1016/j.jbc.2023.104617
Autor:
Daniel Dominguez, Susan Sumner, Blake R. Rushing, Henrik G. Dohlman, Yuanyuan Li, Shuang Li, Sarah E. Harris, Susan McRitchie
Publikováno v:
Biomolecules; Volume 12; Issue 2; Pages: 175
The yeast Saccharomyces cerevisiae has long been used to produce alcohol from glucose and other sugars. While much is known about glucose metabolism, relatively little is known about the receptors and signaling pathways that indicate glucose availabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c33b9c495482793a2ca1e4da14a219f
https://pubmed.ncbi.nlm.nih.gov/35204676
https://pubmed.ncbi.nlm.nih.gov/35204676
Autor:
Blake R. Rushing, Susan Sumner, Shuang Li, Janice C. Jones, Daniel Dominguez, Yuanyuan Li, Henrik G. Dohlman, Sarah E. Harris, Susan McRitchie
Publikováno v:
PLoS Genetics, Vol 17, Iss 7, p e1009640 (2021)
PLoS Genetics
PLoS Genetics
Heterotrimeric G proteins were originally discovered through efforts to understand the effects of hormones, such as glucagon and epinephrine, on glucose metabolism. On the other hand, many cellular metabolites, including glucose, serve as ligands for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc22934899df34c7266ff0eee971ef68
https://doaj.org/article/b1d6d008d7d84ee7807ee27521839932
https://doaj.org/article/b1d6d008d7d84ee7807ee27521839932
Autor:
Timothy C. Elston, Henrik G. Dohlman, Nan Hao, James P. Shellhammer, Yang Li, Amy E. Pomeroy, Lorena Dujmusic
Publikováno v:
Yeast. 36:495-518
The pheromone response pathway of the yeast Saccharomyces cerevisiae is a well-established model for the study of G proteins and mitogen-activated protein kinase (MAPK) cascades. Our longstanding ability to combine sophisticated genetic approaches wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3126b2ac027c441d8a713c6c7f279e2
https://doi.org/10.1002/yea.3395
https://doi.org/10.1002/yea.3395