Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Henrik E, Mei"'
Autor:
Marta Ferreira-Gomes, Yidan Chen, Pawel Durek, Hector Rincon-Arevalo, Frederik Heinrich, Laura Bauer, Franziska Szelinski, Gabriela Maria Guerra, Ana-Luisa Stefanski, Antonia Niedobitek, Annika Wiedemann, Marina Bondareva, Jacob Ritter, Katrin Lehmann, Sebastian Hardt, Christian Hipfl, Sascha Hein, Eberhard Hildt, Mareen Matz, Henrik E. Mei, Qingyu Cheng, Van Duc Dang, Mario Witkowski, Andreia C. Lino, Andrey Kruglov, Fritz Melchers, Carsten Perka, Eva V. Schrezenmeier, Andreas Hutloff, Andreas Radbruch, Thomas Dörner, Mir-Farzin Mashreghi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Bone marrow plasma cells (BMPC) are the correlate of humoral immunity, consistently releasing antibodies into the bloodstream. It remains unclear if BMPC reflect different activation environments or maturation of their precursors. Here we de
Externí odkaz:
https://doaj.org/article/6afb3ecd327947ce81ffe2bed6522ae5
Autor:
Kenneth F. Baker, David McDonald, Gillian Hulme, Rafiqul Hussain, Jonathan Coxhead, David Swan, Axel R. Schulz, Henrik E. Mei, Lucy MacDonald, Arthur G. Pratt, Andrew Filby, Amy E. Anderson, John D. Isaacs
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Immune-mediated inflammatory diseases (IMIDs) are typically characterised by relapsing and remitting flares of inflammation. However, the unpredictability of disease flares impedes their study. Addressing this critical knowledge gap, we use
Externí odkaz:
https://doaj.org/article/34a7ab6817b24901ae14c64e18ae1869
Autor:
Axel R. Schulz, Leonard Fiebig, Heike Hirseland, Lisa-Marie Diekmann, Simon Reinke, Sebastian Hardt, Antonia Niedobitek, Henrik E. Mei
Publikováno v:
EBioMedicine, Vol 95, Iss , Pp 104735- (2023)
Summary: Background: SARS-CoV-2 specific antibody-secreting plasma cells (PC) mediating specific humoral immunity have been identified in the human bone marrow (BM) after COVID-19 or vaccination against SARS-CoV-2. However, it remained unclear whethe
Externí odkaz:
https://doaj.org/article/e841c7cf0ba1456ca09588607aa6fba6
Autor:
Daniela Kuzilková, Cristina Bugarin, Katerina Rejlova, Axel R. Schulz, Henrik E. Mei, Maddalena Paganin, Alessandra Biffi, Andrea Biondi, Tomas Kalina, Giuseppe Gaipa
Publikováno v:
Haematologica, Vol 107, Iss 6 (2021)
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive cancer arising from lymphoblasts of T-cell origin. While TALL accounts for only 15% of childhood and 25% of adult ALL, 30% of patients relapse with a poor outcome. Targeted therapy of resis
Externí odkaz:
https://doaj.org/article/23e3db9f9eed457890ee3aac902742cc
Autor:
Annika Wiedemann, Marie Lettau, Ina Wirries, Annemarie Jungmann, Abdulrahman Salhab, Gilles Gasparoni, Henrik E. Mei, Carsten Perka, Jörn Walter, Andreas Radbruch, Andreia C. Lino, Thomas Dörner
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
The functions of bone marrow plasma cells (BMPC) beyond antibody production are not fully elucidated and distinct subsets of BMPC suggest potential different functions. Phenotypic differences were identified for human BMPC depending on CD19 expressio
Externí odkaz:
https://doaj.org/article/e0343bc094fc42fb81cd129a2e315050
Autor:
Marie Burns, Lennard Ostendorf, Robert Biesen, Andreas Grützkau, Falk Hiepe, Henrik E. Mei, Tobias Alexander
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2424 (2021)
Given its uniformly high expression on plasma cells, CD38 has been considered as a therapeutic target in patients with systemic lupus erythematosus (SLE). Herein, we investigate the distribution of CD38 expression by peripheral blood leukocyte lineag
Externí odkaz:
https://doaj.org/article/d2bd787502b24eb28cb252bef2b3591e
Autor:
Ivet A. Yordanova, Friederike Ebner, Axel Ronald Schulz, Svenja Steinfelder, Berit Rosche, Anna Bolze, Friedemann Paul, Henrik E. Mei, Susanne Hartmann
Publikováno v:
Life, Vol 11, Iss 2, p 101 (2021)
Considering their potent immunomodulatory properties, therapeutic applications of Trichuris suis ova (TSO) are studied as potential alternative treatment of autoimmune disorders like multiple sclerosis (MS), rheumatoid arthritis (RA), or inflammatory
Externí odkaz:
https://doaj.org/article/3595f6a288e342869d474fc0305a149f
Autor:
Maddalena Paganin, Alessandra Biffi, Daniela Kuzilkova, Giuseppe Gaipa, Tomas Kalina, Axel Schulz, Andrea Biondi, Katerina Rejlova, Henrik E. Mei, Cristina Bugarin
Publikováno v:
Haematologica. 107:1293-1310
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive cancer arising from lymphoblasts of T-cell origin. While TALL accounts for only 15% of childhood and 25% of adult ALL, 30% of patients relapse with a poor outcome. Targeted therapy of resis
Autor:
Margitta Worm, Valerie Glatzel, Sabine Baumgart, Henrik E. Mei, Till Sörensen, Andreas Grützkau, Guido Heine
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyREFERENCES.
Autor:
Axel R. Schulz, Heike Hirseland, Lisa-Marie Diekmann, Simon Reinke, Sebastian Hardt, Antonia Niedobitek, Henrik E. Mei
Establishment of long-lived plasma cells (PC) in the bone marrow (BM) is important for the development of long-term specific humoral immunity. While SARS-CoV-2-specific, resting, affinity-matured, IgG-secreting plasma cells were described in human bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48bd5917cead9c43119e061f6ea5f7fa
https://doi.org/10.1101/2022.08.11.503574
https://doi.org/10.1101/2022.08.11.503574