Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Henrik Druid"'
Autor:
Albert Elmsjö, Liam J. Ward, Kie Horioka, Shimpei Watanabe, Fredrik C. Kugelberg, Henrik Druid, Henrik Green
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Postmortem metabolomics holds promise for identifying crucial biological markers relevant to death investigations and clinical scenarios. We aimed to assess its applicability in diagnosing hypothermia, a condition lacking definitive biomarke
Externí odkaz:
https://doaj.org/article/58fdd3a26d5c4529808d175f200de58e
Autor:
Ning Zhang, Luuk Harbers, Michele Simonetti, Constantin Diekmann, Quentin Verron, Enrico Berrino, Sara E. Bellomo, Gabriel M. C. Longo, Michael Ratz, Niklas Schultz, Firas Tarish, Peng Su, Bo Han, Wanzhong Wang, Sofia Onorato, Dora Grassini, Roberto Ballarino, Silvia Giordano, Qifeng Yang, Anna Sapino, Jonas Frisén, Kanar Alkass, Henrik Druid, Vassilis Roukos, Thomas Helleday, Caterina Marchiò, Magda Bienko, Nicola Crosetto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Somatic copy number alterations (SCNAs) are pervasive in advanced human cancers, but their prevalence and spatial distribution in early-stage, localized tumors and their surrounding normal tissues are poorly characterized. Here, we perform m
Externí odkaz:
https://doaj.org/article/a7bc352b5e9d473f9b3b201fba7c47d9
Autor:
Hailey Sounart, Enikő Lázár, Yuvarani Masarapu, Jian Wu, Tibor Várkonyi, Tibor Glasz, András Kiss, Erik Borgström, Andrew Hill, Sefanit Rezene, Soham Gupta, Aleksandra Jurek, Anezka Niesnerová, Henrik Druid, Olaf Bergmann, Stefania Giacomello
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-28 (2023)
Abstract Technologies to study localized host–pathogen interactions are urgently needed. Here, we present a spatial transcriptomics approach to simultaneously capture host and pathogen transcriptome-wide spatial gene expression information from hum
Externí odkaz:
https://doaj.org/article/40ebc38f0ce841148f8dd664380d350a
Autor:
Johanna Classon, Margherita Zamboni, Camilla Engblom, Kanar Alkass, Giulia Mantovani, Christian Pou, Dieudonné Nkulikiyimfura, Petter Brodin, Henrik Druid, Jeff Mold, Jonas Frisén
Publikováno v:
Molecular Oncology, Vol 16, Iss 19, Pp 3452-3464 (2022)
Prostate cancer is a heterogeneous disease with a need for new prognostic biomarkers. Human leukocyte antigen (HLA) genes are highly polymorphic genes central to antigen presentation to T‐cells. Two alleles, HLA‐A*02:01 and HLA‐A*24:02, have be
Externí odkaz:
https://doaj.org/article/9acb7be2d0f6479d879f6f4a25f54423
Autor:
Gopalakrishnan Dhanabalan, Tara Wardi Le Maître, Nenad Bogdanovic, Kanar Alkass, Henrik Druid
Publikováno v:
Neurobiology of Disease, Vol 120, Iss , Pp 63-75 (2018)
Chronic alcohol abuse causes cognitive impairments associated with neurodegeneration and volume loss in the human hippocampus. Here, we hypothesize that alcohol reduces the number of granule cells in the human dentate gyrus and consequently contribut
Externí odkaz:
https://doaj.org/article/3705308f6b76420d8b60a0f0166d88cc
Autor:
Vlad Radoi, Gerd Jakobsson, Vinko Palada, Andrej Nikosjkov, Henrik Druid, Lars Terenius, Eva Kosek, Vladana Vukojević
Publikováno v:
Molecules, Vol 27, Iss 7, p 2350 (2022)
The importance of the dynamic interplay between the opioid and the serotonin neuromodulatory systems in chronic pain is well recognized. In this study, we investigated whether these two signalling pathways can be integrated at the single-cell level v
Externí odkaz:
https://doaj.org/article/5f220e6391d74443a52ac19f247f44b6
Autor:
Joshua Moss, Judith Magenheim, Daniel Neiman, Hai Zemmour, Netanel Loyfer, Amit Korach, Yaacov Samet, Myriam Maoz, Henrik Druid, Peter Arner, Keng-Yeh Fu, Endre Kiss, Kirsty L. Spalding, Giora Landesberg, Aviad Zick, Albert Grinshpun, A. M. James Shapiro, Markus Grompe, Avigail Dreazan Wittenberg, Benjamin Glaser, Ruth Shemer, Tommy Kaplan, Yuval Dor
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The methylation status of circulating cell-free DNA (cfDNA) can be informative about recent cell death events. Here the authors present an approach to determine the tissue origins of cfDNA, using a reference methylation atlas of 25 human tissues and
Externí odkaz:
https://doaj.org/article/841a0167145749b69b07423fda860202
Publikováno v:
Biomolecules, Vol 12, Iss 1, p 32 (2021)
Vitreous fluid is commonly collected for toxicological analysis during forensic postmortem investigations. Vitreous fluid is also often analyzed for potassium, sodium, chloride and glucose for estimation of time since death, and for the evaluation of
Externí odkaz:
https://doaj.org/article/d10b0567af8f4ba3ab501e93507ccf52
Autor:
Pedro Réu, Azadeh Khosravi, Samuel Bernard, Jeff E. Mold, Mehran Salehpour, Kanar Alkass, Shira Perl, John Tisdale, Göran Possnert, Henrik Druid, Jonas Frisén
Publikováno v:
Cell Reports, Vol 20, Iss 4, Pp 779-784 (2017)
The hematopoietic system seeds the CNS with microglial progenitor cells during the fetal period, but the subsequent cell generation dynamics and maintenance of this population have been poorly understood. We report that microglia, unlike most other h
Externí odkaz:
https://doaj.org/article/d5fc57428b2e4a8db888448776497858
Autor:
Kirsty L. Spalding, Samuel Bernard, Erik Näslund, Mehran Salehpour, Göran Possnert, Lena Appelsved, Keng-Yeh Fu, Kanar Alkass, Henrik Druid, Anders Thorell, Mikael Rydén, Peter Arner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Lipid turnover in tissues can be calculated from ratios of different carbon isotopes. Here the authors use this approach to study lipid turnover in two distinct adipose tissue depots and find that, in obese individuals, visceral fat is more lipolytic
Externí odkaz:
https://doaj.org/article/b650818ee3aa43a0a056c56d449a3dbc