Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Henrik Dahllof"'
Autor:
Henrik Dahllof, Olivier Radresa, Andreas Nolting, Patrick Raboisson, Eva Nyman, Jeffrey S. Albert
Publikováno v:
The Open Pain Journal. 6:137-153
The Transient Receptor Potential A1 (TRPA1) ion channel has evolved in animals to respond to signals from a variety of sensory stimuli. Many structural determinants of its multimodal activation have been identified to date. TRPA1 activities include r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b34f34f59d5d77bd16a5fa19ff58b7e
https://doi.org/10.2174/1876386301306010137
https://doi.org/10.2174/1876386301306010137
Autor:
Peter Ström, Mcleod Donald A, Anna Breitholtz-Emanuelsson, William L. Heaton, Ylva Terelius, Tao Xin, Louise Edwards, Sheehan Susan M, Keith Jarvie, Anna Nordmark, David Wensbo, Patrick Raboisson, Henrik Dahllof, Abdelmalik Slassi, Alexander Minidis, Methvin Isaac, Julie Wilson, Annika Kers
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(22)
AZD9272 and AZD6538 are two novel mGluR5 negative allosteric modulators selected for further clinical development. An initial high-throughput screening revealed leads with promising profiles, which were further optimized by minor, yet indispensable,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc87dc7298442b699484fa807110d2b
https://pubmed.ncbi.nlm.nih.gov/23046966
https://pubmed.ncbi.nlm.nih.gov/23046966