Characterization of the TNF and IL-1 systems in human brain and blood after ischemic stroke

Autor: Bettina H. Clausen, Martin Wirenfeldt, Sofie S. Høgedal, Lars H. Frich, Helle H. Nielsen, Henrik D. Schrøder, Kamilla Østergaard, Bente Finsen, Bjarne W. Kristensen, Kate L. Lambertsen

Publikováno v: Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)

Abstract Preclinical and clinical proof-of-concept studies have suggested the effectiveness of pharmacological modulation of inflammatory cytokines in ischemic stroke. Experimental evidence shows that targeting tumor necrosis factor (TNF) and interle

Externí odkaz: https://doaj.org/article/3cae400332a44bbd9ebeeae911cf0139

Myopathy as a cause of Long COVID fatigue:Evidence from quantitative and single fiber EMG and muscle histopathology

Autor: Jane Agergaard, Benjamin Yamin Ali Khan, Thomas Engell-Sørensen, Berit Schiøttz-Christensen, Lars Østergaard, Eva K. Hejbøl, Henrik D. Schrøder, Henning Andersen, Jakob Udby Blicher, Thomas Holm Pedersen, Thomas Harbo, Hatice Tankisi, Anders Lehmann Dahl Pedersen, Andreas Fløe Hvass, Cagla Cömert, Christoffer Laustsen, Elisabeth Bendstrup, Gregory Wood, Hans Erik Bøtker, Johan Palmfeldt, Kristoffer Skaalum, Lars Jørgen Østergaard, Line Vibholm, Martin Mølhave, Rikke Katrine Jentoft Olsen, Sofie Eg Jørgensen, Steen Hvitfeldt Poulsen, Steffen Leth, Søren Sperling Haugen, Trine H. Mogensen, William Ullahammer, Won-Yong Kim

Publikováno v: Agergaard, J, Yamin Ali Khan, B, Engell-Sørensen, T, Schiøttz-Christensen, B, Østergaard, L, Hejbøl, E K, Schrøder, H D, Andersen, H, Blicher, J U, Holm Pedersen, T, Harbo, T, Tankisi, H & MULTICOV Consortium 2023, ' Myopathy as a cause of Long COVID fatigue : Evidence from quantitative and single fiber EMG and muscle histopathology ', Clinical Neurophysiology, vol. 148, pp. 65-75 . https://doi.org/10.1016/j.clinph.2023.01.010
MULTICOV Consortium 2023, ' Myopathy as a cause of Long COVID fatigue : Evidence from quantitative and single fiber EMG and muscle histopathology ', Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, vol. 148, pp. 65-75 . https://doi.org/10.1016/j.clinph.2023.01.010
Agergaard, J, Yamin Ali Khan, B, Engell-Sørensen, T, Schiøttz-Christensen, B, Jørgen Østergaard, L, Hejbøl, E K, Schrøder, H D, Andersen, H, Blicher, J U, Holm Pedersen, T, Harbo, T, Tankisi, H & MULTICOV Consortium 2023, ' Myopathy as a cause of Long COVID fatigue : Evidence from quantitative and single fiber EMG and muscle histopathology ', Clinical Neurophysiology, vol. 148, pp. 65-75 . https://doi.org/10.1016/j.clinph.2023.01.010

ObjectiveTo describe neurophysiological abnormalities in Long COVID and correlate quantitative electromyography (qEMG) and single fiber EMG (sfEMG) results to clinical scores and histopathology.Methods84 patients with non-improving musculoskeletal Lo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d24d6dc9fbbe811be63c9d75c347c7b
https://vbn.aau.dk/da/publications/ab3d1258-616a-438e-96be-f1f08a865ff4

CL-L1 and CL-K1 Exhibit Widespread Tissue Distribution With High and Co-Localized Expression in Secretory Epithelia and Mucosa

Autor: Soren W. K. Hansen, Josephine B. Aagaard, Karen B. Bjerrum, Eva K. Hejbøl, Ole Nielsen, Henrik D. Schrøder, Karsten Skjoedt, Anna L. Sørensen, Jonas H. Graversen, Maiken L. Henriksen

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Collectin liver 1 (CL-L1, alias collectin 10) and collectin kidney 1 (CL-K1, alias collectin 11) are oligomeric pattern recognition molecules associated with the complement system, and mutations in either of their genes may lead to deficiency and dev

Externí odkaz: https://doaj.org/article/172edd8b29eb460780aed8ce801ef805

Myopathy as a cause of fatigue in long-term post-COVID-19 symptoms:Evidence of skeletal muscle histopathology

Autor: Eva K. Hejbøl, Thomas Harbo, Jane Agergaard, Line B. Madsen, Thomas H. Pedersen, Lars J. Østergaard, Henning Andersen, Henrik D. Schrøder, Hatice Tankisi

Publikováno v: Hejbøl, E K, Harbo, T, Agergaard, J, Madsen, L B, Pedersen, T H, Østergaard, L J, Andersen, H, Schrøder, H D & Tankisi, H 2022, ' Myopathy as a cause of fatigue in long-term post-COVID-19 symptoms : Evidence of skeletal muscle histopathology ', European Journal of Neurology, vol. 29, no. 9, pp. 2832-2841 . https://doi.org/10.1111/ene.15435

Background and purpose: Among post-COVID-19 symptoms, fatigue is reported as one of the most common, even after mild acute infection, and as the cause of fatigue, myopathy diagnosed by electromyography has been proposed in previous reports. This stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ace94fe0aa5e4cf01851be87665516
https://pure.au.dk/portal/da/publications/myopathy-as-a-cause-of-fatigue-in-longterm-postcovid19-symptoms(856ccde2-b793-471e-a970-c8000c87a205).html

Delta-like 1 homolog (dlk1): a marker for rhabdomyosarcomas implicated in skeletal muscle regeneration.

Autor: Louise H Jørgensen, Jeeva Sellathurai, Erica E Davis, Tania Thedchanamoorthy, Rua W A Al-Bader, Charlotte H Jensen, Henrik D Schrøder

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e60692 (2013)

Dlk1, a member of the Epidermal Growth Factor family, is expressed in multiple tissues during development, and has been detected in carcinomas and neuroendocrine tumors. Dlk1 is paternally expressed and belongs to a group of imprinted genes associate

Externí odkaz: https://doaj.org/article/414db9b807ed4418baacb15a9dc1f763