A 7-Gene Signature Depicts the Biochemical Profile of Early Prefibrotic Myelofibrosis.

Autor: Vibe Skov, Mark Burton, Mads Thomassen, Thomas Stauffer Larsen, Caroline H Riley, Ann Brinch Madelung, Lasse Kjær, Henrik Bondo, Inger Stamp, Mats Ehinger, Rasmus Dahl-Sørensen, Nana Brochmann, Karsten Nielsen, Jürgen Thiele, Morten K Jensen, Ole Weis Bjerrum, Torben A Kruse, Hans Carl Hasselbalch

Publikováno v: PLoS ONE, Vol 11, Iss 8, p e0161570 (2016)

Recent studies have shown that a large proportion of patients classified as essential thrombocythemia (ET) actually have early primary prefibrotic myelofibrosis (prePMF), which implies an inferior prognosis as compared to patients being diagnosed wit

Externí odkaz: https://doaj.org/article/e8a77e96cb5f4691a2d728bdace4470e

A 7-Gene Signature Depicts the Biochemical Profile of Early Prefibrotic Myelofibrosis

Autor: Mark Burton, Ole Weis Bjerrum, Rasmus Dahl-Sørensen, Inger Stamp, Henrik Bondo, Mats Ehinger, Lasse Kjær, Caroline Hasselbalch Riley, Thomas Stauffer Larsen, Vibe Skov, Mads Thomassen, Nana Brochmann, Morten K. Jensen, Karsten Bork Nielsen, Torben A Kruse, Jürgen Thiele, Ann Brinch Madelung, Hans Carl Hasselbalch

Publikováno v: PLoS ONE, Vol 11, Iss 8, p e0161570 (2016)
Skov, V, Burton, M, Thomassen, M, Stauffer Larsen, T, Riley, C H, Brinch Madelung, A, Kjær, L, Bondo, H, Stamp, I, Ehinger, M, Dahl-Sørensen, R, Brochmann Mortensen, N, Nielsen, K, Thiele, J, Jensen, M K, Weis Bjerrum, O, Kruse, T A & Hasselbalch, H C 2016, ' A 7-Gene Signature Depicts the Biochemical Profile of Early Prefibrotic Myelofibrosis ', P L o S One, vol. 11, no. 8, e0161570, pp. 1-15 . https://doi.org/10.1371/journal.pone.0161570
Skov, V, Burton, M, Thomassen, M, Larsen, T S, Hasselbalch Riley, C, Brinch Madelung, A, Kjær, L, Bondo, H, Stamp, I, Ehinger, M, Dahl-Sørensen, R, Brochmann Mortensen, N, Nielsen, K, Thiele, J, Jensen, M K, Kruse, T A, Bjerrum, O W & Hasselbalch, H C 2015, ' A 7-gene signature depicts the biochemical profile of early prefibrotic myelofibrosis ', Haematologica, vol. 100, no. S1, E1315, pp. 526 . < http://www.haematologica.org/content/100/supplement_1/1.full-text.pdf+html >
Skov, V, Burton, M, Thomassen, M, Stauffer Larsen, T, Riley, C H, Madelung, A B, Kjaer, L, Bondo, H, Stamp, I, Ehinger, M, Dahl-Sørensen, R, Brochmann, N, Nielsen, K, Thiele, J, Jensen, M K, Weis Bjerrum, O, Kruse, T A & Hasselbalch, H C 2016, ' A 7-Gene Signature Depicts the Biochemical Profile of Early Prefibrotic Myelofibrosis ', PLoS ONE, vol. 11, no. 8, e0161570 . https://doi.org/10.1371/journal.pone.0161570
PLoS ONE
Skov, V, Burton, M, Thomassen, M, Larsen, T S, Hasselbalch Riley, C, Brinch Madelung, A, Kjær, L, Bondo, H, Stamp, I, Ehinger, M, Dahl-Sørensen, R, Brochmann Mortensen, N, Nielsen, K, Thiele, J, Jensen, M K, Bjerrum, O W, Kruse, T A & Hasselbalch, H C 2015, ' A 7-gene signature depicts the biochemical profile of early prefibrotic myelofibrosis ', 20th Congress of European Hematology Association (EHA), Vienna, Austria, 11/06/2015-14/06/2015 . < http://www.haematologica.org/content/100/supplement_1/1.full-text.pdf+html >

Recent studies have shown that a large proportion of patients classified as essential thrombocythemia (ET) actually have early primary prefibrotic myelofibrosis (prePMF), which implies an inferior prognosis as compared to patients being diagnosed wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec730adb992830a8c13265816d20991
http://europepmc.org/articles/PMC5007012?pdf=render

The JAK2V617F allele burden and STAT3- and STAT5 phosphorylation in myeloproliferative neoplasms: early prefibrotic myelofibrosis compared with essential thrombocythemia, polycythemia vera and myelofibrosis

Autor: Hans Carl Hasselbalch, Malene Risum, Michael Bzorek, Ann Brinch Madelung, Michael Holmsgaard Kristensen, Inger Stamp, Henrik Bondo

Publikováno v: APMIS. 119:498-504

Early prefibrotic myelofibrosis (early PMF) is a diagnosis that clinically and histologically mimic essential thrombocythemia (ET), but is important to distinguish from ET, polycythemia vera (PV) and primary myelofibrosis (PMF) due to its different p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b518afaf90497d66b87f8651862b45c1
https://doi.org/10.1111/j.1600-0463.2011.02754.x

World Health Organization-defined classification of myeloproliferative neoplasms: morphological reproducibility and clinical correlations--the Danish experience

Autor: Nana Brochmann Mortensen, Elisabeth Ralfkiaer, Preben Loevgreen, Rasmus Dahl-Sørensen, Inger Stamp, Signe Ledou Nielsen, Anne Falensteen, Henrik Bondo, Juergen Thiele, Hans Carl Hasselbalch, Kira Dynnes Svendsen, Helle Charlotte Knudsen, Mats Ehinger, Theis Lange, Ann Brinch Madelung, Karsten Bork Nielsen

Publikováno v: American journal of hematology. 88(12)

We examined inter-and intraobserver reproducibility and concordance between histological diagnosis and independently collected clinical findings in a large series of patients with the major subtypes of myeloproliferative neoplasms (MPNs) and controls

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4928bbdd292a80774f856e33b9a3704a
https://pubmed.ncbi.nlm.nih.gov/23897670

A Novel Immunohistochemical Sequential Multi-Labelling and Erasing Technique Enables Epitope Characterization of Bone Marrow Pericytes In Primary Myelofibrosis

Autor: Henrik Bondo, Hans Carl Hasselbalch, Ole Weis Bjerrum, Ann Brinch Madelung, Stefan Scheding, Eva Zetterberg, Elisabeth Ralfkiaer, Michael Bzorek

Publikováno v: Blood. 116:4108-4108

Abstract 4108 Background: In Philadelphia-negative chronic myeloproliferative neoplasms (MPN) increased microvascular density, bizarre vessel architecture and increased number of pericytes are distinct histopathological features; apart from the chara

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66970b2c1bb0d8f6f8e22b82efc6737
https://doi.org/10.1182/blood.v116.21.4108.4108