Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Henrik Berg, Rasmussen"'
Publikováno v:
Viruses, Vol 15, Iss 11, p 2151 (2023)
Molnupiravir, a prodrug known for its broad antiviral activity, has demonstrated efficacy in animal models of COVID-19, prompting clinical trials, in which initial results indicated a significant effect against the disease. However, subsequent clinic
Externí odkaz:
https://doaj.org/article/f37a25a13f94440db0409dbcafc4f0c6
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 2, Pp n/a-n/a (2022)
Abstract GS‐441524, the parent nucleoside of remdesivir, has been proposed to be effective against Covid‐19 based on in vitro studies and studies in animals. However, randomized clinical trials of the agent to treat Covid‐19 have not been condu
Externí odkaz:
https://doaj.org/article/32186d0650fd4671ab3d1c8e5578a41c
Autor:
Yanisa Wannasuphoprasit, Stig Ejdrup Andersen, Maria J. Arranz, Rosa Catalan, Gesche Jurgens, Sanne Maartje Kloosterboer, Henrik Berg Rasmussen, Anjali Bhat, Haritz Irizar, Dora Koller, Renato Polimanti, Baihan Wang, Eirini Zartaloudi, Isabelle Austin-Zimmerman, Elvira Bramon
Publikováno v:
Frontiers in Psychology, Vol 12 (2022)
BackgroundAntipsychotic-induced weight gain is a contributing factor in the reduced life expectancy reported amongst people with psychotic disorders. CYP2D6 is a liver enzyme involved in the metabolism of many commonly used antipsychotic medications.
Externí odkaz:
https://doaj.org/article/329a6163499a42ae9f34e1da18f61c33
Autor:
Kristine Kaalund-Brok, Tine Bodil Houmann, Marie Bang Hebsgaard, Maj-Britt Glenn Lauritsen, Louise Hyldborg Lundstrøm, Helene Grønning, Lise Darling, Susanna Reinert-Petersen, Morten Aagaard Petersen, Jens Richardt Møllegaard Jepsen, Anne Katrine Pagsberg, Kerstin Jessica Plessen, Henrik Berg Rasmussen, Pia Jeppesen, INDICES
Publikováno v:
PLoS ONE, Vol 16, Iss 10 (2021)
Randomized placebo-controlled trials have reported efficacy of methylphenidate (MPH) for Attention-deficit/hyperactivity disorder (ADHD); however, selection biases due to strict entry criteria may limit the generalizability of the findings. Few ecolo
Externí odkaz:
https://doaj.org/article/a18b6895a9af481db2c0e3811f35a663
Autor:
Henrik Berg Rasmussen, Gesche Jürgens, Ragnar Thomsen, Olivier Taboureau, Kornelius Zeth, Poul Erik Hansen, Peter Riis Hansen
Publikováno v:
Viruses, Vol 13, Iss 7, p 1369 (2021)
GS-441524 is an adenosine analog and the parent nucleoside of the prodrug remdesivir, which has received emergency approval for treatment of COVID-19. Recently, GS-441524 has been proposed to be effective in the treatment of COVID-19, perhaps even be
Externí odkaz:
https://doaj.org/article/15d61dbd3e404e23840e2bbba81147ee
Autor:
Eliane Briand, Ragnar Thomsen, Kristian Linnet, Henrik Berg Rasmussen, Søren Brunak, Olivier Taboureau
Publikováno v:
Molecules, Vol 24, Iss 15, p 2747 (2019)
The human carboxylesterase 1 (CES1), responsible for the biotransformation of many diverse therapeutic agents, may contribute to the occurrence of adverse drug reactions and therapeutic failure through drug interactions. The present study is designed
Externí odkaz:
https://doaj.org/article/7affc93356584c2db179bea78e015466
Publikováno v:
Rasmussen, H B, Thomsen, R & Hansen, P R 2022, ' Nucleoside analog GS-441524 : pharmacokinetics in different species, safety, and potential effectiveness against Covid-19 ', Pharmacology Research and Perspectives, vol. 10, no. 2, e00945 . https://doi.org/10.1002/prp2.945
GS-441524, the parent nucleoside of remdesivir, has been proposed to be effective against Covid-19 based on in vitro studies and studies in animals. However, randomized clinical trials of the agent to treat Covid-19 have not been conducted. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e37852a62cdaccc7a11ce6bb3d848496
https://curis.ku.dk/portal/da/publications/nucleoside-analog-gs441524(696d57b6-80ce-4a8b-8a26-224c2fce3c7d).html
https://curis.ku.dk/portal/da/publications/nucleoside-analog-gs441524(696d57b6-80ce-4a8b-8a26-224c2fce3c7d).html
Autor:
Karl Emil Nelveg-Kristensen, Majbritt Busk Madsen, Christian Torp-Pedersen, Lars Køber, Martin Egfjord, Henrik Berg Rasmussen, Peter Riis Hansen
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144195 (2015)
Evidence for pharmacogenetic risk stratification of angiotensin-converting enzyme inhibitor (ACEI) treatment is limited. Therefore, in a cohort of ACEI-treated patients with congestive heart failure (CHF), we investigated the predictive value of two
Externí odkaz:
https://doaj.org/article/98d42e7367864356872c4568c07e928a
Autor:
Martin Friedrichsen, Pernille Poulsen, Jørgen Wojtaszewski, Peter Riis Hansen, Allan Vaag, Henrik Berg Rasmussen
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56861 (2013)
CONTEXT AND AIMS: Carboxylesterase 1 (CES1) appears to play an important role in the control of the metabolism of triglycerides and cholesterol in adipocytes and other cell types including hepatocytes. Therefore, it is relevant to gain insights into
Externí odkaz:
https://doaj.org/article/cf5441dc443f48b8b01dbc2a40c1c6f2
Publikováno v:
Ugeskrift for laeger. 176(6)
Until now drug therapy has primarily been controlled by dose titration on the basis of effects and side effects. However, a lot of people being treated with a drug experience too little effect or too many side effects. Therefore it will be advantageo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27be78bc29459e830e9a6bfff700deb4
https://pubmed.ncbi.nlm.nih.gov/25096206
https://pubmed.ncbi.nlm.nih.gov/25096206