Screening archaeological bone for palaeogenetic and palaeoproteomic studies.

Autor: Ioannis Kontopoulos, Kirsty Penkman, Victoria E Mullin, Laura Winkelbach, Martina Unterländer, Amelie Scheu, Susanne Kreutzer, Henrik B Hansen, Ashot Margaryan, Matthew D Teasdale, Birgit Gehlen, Martin Street, Niels Lynnerup, Ioannis Liritzis, Adamantios Sampson, Christina Papageorgopoulou, Morten E Allentoft, Joachim Burger, Daniel G Bradley, Matthew J Collins

Publikováno v: PLoS ONE, Vol 15, Iss 6, p e0235146 (2020)

The recovery and analysis of ancient DNA and protein from archaeological bone is time-consuming and expensive to carry out, while it involves the partial or complete destruction of valuable or rare specimens. The fields of palaeogenetic and palaeopro

Externí odkaz: https://doaj.org/article/f5fced8d050e47a098488355bce1586f

Data from Remodeling of the Tumor Microenvironment Predicts Increased Risk of Cancer in Postmenopausal Women: The Prospective Epidemiologic Risk Factor (PERF I) Study

Autor: Morten Karsdal, Estrid Høgdall, Claus Christiansen, Jesper Skov Neergaard, Katrine Dragsbæk, Diana J. Leeming, Anne-Christine Bay-Jensen, Henrik B. Hansen, Stephanie N. Kehlet, Nicholas Willumsen, Cecilie L. Bager

Background: An altered tumor microenvironment is one of the earliest signs of cancer and an important driver of the disease. We have seen previously that biomarkers reflecting tumor microenvironment modifications, such as matrix metalloproteinase (MM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2a9b0a03895007857f80f7361ddda3
https://doi.org/10.1158/1055-9965.c.6515938.v1

Metabolic, biochemical, histopathological and transcriptomic effects of long-acting FGF21 analogue in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH

Autor: Malte H. Nielsen, Denise Oró, Henrik B. Hansen, Matthew Gillum, Michael Feigh

Publikováno v: Journal of Hepatology. 77:S669

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b129fbe6cb57c369bb835b978104b2b
https://doi.org/10.1016/s0168-8278(22)01657-9

Screening archaeological bone for palaeogenetic and palaeoproteomic studies

Autor: Victoria E. Mullin, Christina Papageorgopoulou, Matthew D. Teasdale, Henrik B. Hansen, Birgit Gehlen, Joachim Burger, Ashot Margaryan, Adamantios Sampson, Laura Winkelbach, Niels Lynnerup, Kirsty Penkman, Daniel G. Bradley, Amelie Scheu, Morten E. Allentoft, Martina Unterländer, Ioannis Liritzis, Matthew J. Collins, Ioannis Kontopoulos, Martin Street, Susanne Kreutzer

Publikováno v: PLoS ONE
Kontopoulos, I, Penkman, K, Mullin, V E, Winkelbach, L, Unterländer, M, Scheu, A, Kreutzer, S, Hansen, H B, Margaryan, A, Teasdale, M D, Gehlen, B, Street, M, Lynnerup, N, Liritzis, I, Sampson, A, Papageorgopoulou, C, Allentoft, M E, Burger, J, Bradley, D G & Collins, M J 2020, ' Screening archaeological bone for palaeogenetic and palaeoproteomic studies ', PLoS ONE, vol. 15, no. 6, e0235146 . https://doi.org/10.1371/journal.pone.0235146
PLoS ONE, Vol 15, Iss 6, p e0235146 (2020)

Funder: FP7 Ideas: European Research Council; funder-id: http://dx.doi.org/10.13039/100011199; Grant(s): 295729
The recovery and analysis of ancient DNA and protein from archaeological bone is time-consuming and expensive to carry out, while it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6401e568f26b46c7ab0a3f376c5efb90
https://pubmed.ncbi.nlm.nih.gov/32584871

Ancient pathogen DNA in human teeth and petrous bones

Autor: Niels Lynnerup, Eske Willerslev, Levon Yepiskoposyan, Morten E. Allentoft, Martin Sikora, Henrik B. Hansen, Vyacheslav Moiseyev, Liivi Varul, Simon Rasmussen, Alexandr Khoklov, Lehti Saag, Andrey Epimakhov, Ashot Margaryan, Aivar Kriiska

Publikováno v: Margaryan, A, Hansen, H B, Rasmussen, S, Sikora, M, Moiseyev, V, Khoklov, A, Epimakhov, A, Yepiskoposyan, L, Kriiska, A, Varul, L, Saag, L, Lynnerup, N, Willerslev, E & Allentoft, M E 2018, ' Ancient pathogen DNA in human teeth and petrous bones ', Ecology and Evolution, vol. 8, no. 6, pp. 3534-3542 . https://doi.org/10.1002/ece3.3924
Ecology and Evolution
Margaryan, A, Hansen, H, Rasmussen, S, Sikora, M, Moiseyev, V, Khoklov, A, Epimakhov, A, Yepiskoposyan, L, Kriiska, A, Varul, L, Saag, L, Lynnerup, N, Willerslev, E & Allentoft, M E 2018, ' Ancient pathogen DNA in human teeth and petrous bones ', Ecology and Evolution, vol. 8, no. 6, pp. 3534-3542 . https://doi.org/10.1002/ece3.3924

Recent ancient DNA (aDNA) studies of human pathogens have provided invaluable insights into their evolutionary history and prevalence in space and time. Most of these studies were based on DNA extracted from teeth or postcranial bones. In contrast, n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a46429a50467aceef72feb83f2ff11
https://orbit.dtu.dk/en/publications/4f1fe460-f41f-40b7-a1c4-7e95bc180a80