Zobrazeno 1 - 10
of 3 113
pro vyhledávání: '"Henrik, Zetterberg."'
Autor:
Miray Budak, Bernadette A. Fausto, Zuzanna Osiecka, Mustafa Sheikh, Robert Perna, Nicholas Ashton, Kaj Blennow, Henrik Zetterberg, Patricia Fitzgerald-Bocarsly, Mark A. Gluck
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background Phosphorylated tau (p-tau) and amyloid beta (Aβ) in human plasma may provide an affordable and minimally invasive method to evaluate Alzheimer’s disease (AD) pathophysiology. The medial temporal lobe (MTL) is susceptible to cha
Externí odkaz:
https://doaj.org/article/69d75a1a6fe74422a93d9adb3aba651c
Autor:
Anna Hofmann, Lisa M. Häsler, Marius Lambert, Stephan A. Kaeser, Susanne Gräber-Sultan, Ulrike Obermüller, Elke Kuder-Buletta, Christian la Fougere, Christoph Laske, Jonathan Vöglein, Johannes Levin, Nick C. Fox, Natalie S. Ryan, Henrik Zetterberg, Jorge J. Llibre-Guerra, Richard J. Perrin, Laura Ibanez, Peter R. Schofield, William S. Brooks, Gregory S. Day, Martin R. Farlow, Ricardo F. Allegri, Patricio Chrem Mendez, Takeshi Ikeuchi, Kensaku Kasuga, Jae-Hong Lee, Jee Hoon Roh, Hiroshi Mori, Francisco Lopera, Randall J. Bateman, Eric McDade, Brian A. Gordon, Jasmeer P. Chhatwal, Mathias Jucker, Stephanie A. Schultz, Dominantly Inherited Alzheimer Network
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Disease-modifying therapies for Alzheimer’s disease (AD) are likely to be most beneficial when initiated in the presymptomatic phase. To track the benefit of such interventions, fluid biomarkers are of great importance, with neurofilament
Externí odkaz:
https://doaj.org/article/0a454b50306942c5b151db45a71682b3
Autor:
Corey J. Bolton, Omair A. Khan, Dandan Liu, Sydney Wilhoite, Logan Dumitrescu, Amalia Peterson, Kaj Blennow, Henrik Zetterberg, Timothy J. Hohman, Angela L. Jefferson, Katherine A. Gifford
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 11, Pp 2977-2986 (2024)
Abstract Objective This study examined the effect of cognitive status, education, and sex on the association between subjective cognitive decline (SCD) and Alzheimer's disease (AD) biomarkers in non‐demented older adults. Methods Vanderbilt Memory
Externí odkaz:
https://doaj.org/article/b82a3c97a2f8422bb0313931c9a5a88b
Autor:
Evgeniia Lobanova, Yu P. Zhang, Derya Emin, Jack Brelstaff, Lakmini Kahanawita, Maura Malpetti, Annelies Quaegebeur, Kathy Triantafilou, Martha Triantafilou, Henrik Zetterberg, James B. Rowe, Caroline H. Williams-Gray, Clare Elizabeth Bryant, David Klenerman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Immunotherapeutic strategies for Alzheimer’s and Parkinson’s disease would be facilitated by better measures of inflammation. Here we established an ultra-sensitive single-molecule pull-down immunoassay combined with direct stochastic op
Externí odkaz:
https://doaj.org/article/3b89562d5e954dab9038f1d373df047b
Autor:
Karl Götze, Agathe Vrillon, Julien Dumurgier, Sandrine Indart, Marta Sanchez-Ortiz, Hela Slimi, Agathe Raynaud-Simon, Emmanuel Cognat, Matthieu Martinet, Henrik Zetterberg, Kaj Blennow, Claire Hourrègue, Elodie Bouaziz-Amar, Claire Paquet, Matthieu Lilamand
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Analysis of selected research cohorts has highlighted an association between plasma neurofilament light (NfL) protein and cross-sectional cognitive impairment as well as longitudinal cognitive decline. However, the findings have y
Externí odkaz:
https://doaj.org/article/72b22a4a79ff4ee783c0c7dbfa0db7ee
Autor:
Erik Fernström, Marianne Jarfelt, Malin Blomstrand, Birgitta Lannering, Markus Axelsson, Pontus Wasling, Thomas Björk‐Eriksson, Henrik Zetterberg, Marie Kalm
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 9, Pp 2382-2391 (2024)
Abstract Objective Treatment of pediatric brain tumors is associated with potential long‐term cognitive sequelae. Patients treated with craniospinal irradiation for posterior fossa tumors are at high risk. New biomarkers that could help to differen
Externí odkaz:
https://doaj.org/article/78b83252c8e6406496757c9868acf92b
Autor:
Charlotte Johansson, Steinunn Thordardottir, José Laffita-Mesa, Josef Pannee, Elena Rodriguez-Vieitez, Henrik Zetterberg, Kaj Blennow, Caroline Graff
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Several blood-based biomarkers offer the opportunity of in vivo detection of brain pathology and neurodegeneration in Alzheimer disease with high specificity and sensitivity, but the performance of amyloid-β (Aβ) measurements re
Externí odkaz:
https://doaj.org/article/f749f6d7e7b74fc1adaf158a55ea204e
Autor:
Ciro della Monica, Victoria Revell, Giuseppe Atzori, Rhiannon Laban, Simon S. Skene, Amanda Heslegrave, Hana Hassanin, Ramin Nilforooshan, Henrik Zetterberg, Derk-Jan Dijk
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Plasma biomarkers of dementia, including phosphorylated tau (p-tau217), offer promise as tools for diagnosis, stratification for clinical trials, monitoring disease progression, and assessing the success of interventions in those living with
Externí odkaz:
https://doaj.org/article/b7a19a55d5b447cca927ff0807044a82
Autor:
Makrina Daniilidou, Jasper Holleman, Göran Hagman, Ingemar Kåreholt, Malin Aspö, Ann Brinkmalm, Henrik Zetterberg, Kaj Blennow, Alina Solomon, Miia Kivipelto, Shireen Sindi, Anna Matton
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Cortisol dysregulation, neuroinflammation, and cerebrovascular dysfunction are biological processes that have been separately shown to be affected in Alzheimer’s disease (AD). Here, we aimed to identify biomarker signatures reflecting thes
Externí odkaz:
https://doaj.org/article/8c7751df030843d785cebe6217f0dcf6
Autor:
Camilla Christina Pedersen, Anastasia Ushakova, Guido Alves, Ole-Bjørn Tysnes, Kaj Blennow, Henrik Zetterberg, Jodi Maple-Grødem, Johannes Lange
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-6 (2024)
Abstract Neurofilament light chain (NFL) is elevated in neurodegenerative diseases, including Parkinson’s disease (PD). This study aimed to investigate serum NFL in newly diagnosed PD and its association with cognitive and motor decline over 10 yea
Externí odkaz:
https://doaj.org/article/87330a2ead404de697c1a54b4b1471e8