Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Henriikka, Salomäki"'
Autor:
Liisa Ailanen, Laura H. Vähätalo, Henriikka Salomäki-Myftari, Satu Mäkelä, Wendy Orpana, Suvi T. Ruohonen, Eriika Savontaus
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Neuropeptide Y (NPY) plays an important role in the regulation of energy homeostasis in the level of central and sympathetic nervous systems (SNSs). Genetic silencing of peripheral Y2-receptors have anti-obesity effects, but it is not known whether p
Externí odkaz:
https://doaj.org/article/4a3992cdb7554a42ae1429f6a7586366
Autor:
Henriikka Salomäki-Myftari, Laura H Vähätalo, Liisa Ailanen, Sami Pietilä, Asta Laiho, Arno Hänninen, Juha-Pekka Pursiheimo, Eveliina Munukka, Anniina Rintala, Eriika Savontaus, Ullamari Pesonen, Markku Koulu
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163805 (2016)
Prenatal metformin exposure has been shown to improve the metabolic outcome in the offspring of high fat diet fed dams. However, if this is evident also in a genetic model of obesity and whether gut microbiota has a role, is not known.The metabolic e
Externí odkaz:
https://doaj.org/article/9bf86201797f4bf58d8875ad9cd37f3c
Autor:
Annele Sainio, Hannu Järveläinen, Piia Takabe, Markku Koulu, Mirva Söderström, Sanna Oikari, Henriikka Salomäki-Myftari, Sanna Pasonen-Seppänen
Publikováno v:
Journal of Investigative Medicine
Metformin is the first-line drug in the treatment of type 2 diabetes worldwide based on its effectiveness and cardiovascular safety. Currently metformin is increasingly used during pregnancy in women with gestational diabetes mellitus, even if the lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2de9fd689345caf55484c83990b91b3
http://europepmc.org/articles/PMC7063400
http://europepmc.org/articles/PMC7063400
Autor:
Henriikka Salomäki, Merja Heinäniemi, Laura H Vähätalo, Liisa Ailanen, Kim Eerola, Suvi T Ruohonen, Ullamari Pesonen, Markku Koulu
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115778 (2014)
AIMS: Despite the wide use of metformin in metabolically challenged pregnancies, the long-term effects on the metabolism of the offspring are not known. We studied the long-term effects of prenatal metformin exposure during metabolically challenged p
Externí odkaz:
https://doaj.org/article/20a301e0e5534513a7ee092d49598223
Autor:
Henriikka Salomäki, Laura H. Vähätalo, Kirsti Laurila, Norma T. Jäppinen, Anna-Maija Penttinen, Liisa Ailanen, Juan Ilyasizadeh, Ullamari Pesonen, Markku Koulu
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/738516bf30d1464e9dfa6ef3a31cd1f5
Autor:
Henriikka Salomäki, Laura H Vähätalo, Kirsti Laurila, Norma T Jäppinen, Anna-Maija Penttinen, Liisa Ailanen, Juan Ilyasizadeh, Ullamari Pesonen, Markku Koulu
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56594 (2013)
AIMS: The antidiabetic drug metformin is currently used prior and during pregnancy for polycystic ovary syndrome, as well as during gestational diabetes mellitus. We investigated the effects of prenatal metformin exposure on the metabolic phenotype o
Externí odkaz:
https://doaj.org/article/9357303844824bc98ca8dfa735fc3a2c
Autor:
Laura H. Vähätalo, Kim Eerola, Asta Laiho, Helena Gylling, Henriikka Salomäki-Myftari, Katja Tuomainen, Eriika Savontaus, Markku Ahotupa, Liisa Ailanen, Suvi T. Ruohonen, Matias Röyttä
Publikováno v:
The Journal of endocrinology. 234(1)
A gain-of-function polymorphism in human neuropeptide Y (NPY) gene (rs16139) associates with metabolic disorders and earlier onset of type 2 diabetes (T2D). Similarly, mice overexpressing NPY in noradrenergic neurons (OE-NPYDBH) display obesity and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959402cc7880d8025cc1241bc21336b2
https://pubmed.ncbi.nlm.nih.gov/28468933
https://pubmed.ncbi.nlm.nih.gov/28468933
Autor:
Henriikka Salomäki, Petr Pavek, Marcin Buler, Jukka Hakkola, Markku Koulu, Sanna-Mari Aatsinki
Publikováno v:
British Journal of Pharmacology. 171:2351-2363
Background and Purpose The objective of this study was to determine how the AMPK activating antidiabetic drug metformin affects the major activator of hepatic gluconeogenesis, PPARγ coactivator 1α (PGC-1α) and liver functions regulated by PGC-1α.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afa3efe674dc4aadc5de65ad06367e5e
https://doi.org/10.1111/bph.12585
https://doi.org/10.1111/bph.12585
Autor:
Petteri Rinne, Pekka Saukko, Emilia Koskinen, Juhani Knuuti, Henriikka Salomäki, Heidi Liljenbäck, Salla Nuutinen, Mia Ståhle, Anne Roivainen, Sanna Hellberg, Johanna M.U. Silvola, Eriika Savontaus, Antti Saraste
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34(7):1346-54
Objective— Melanocortin peptides have been shown to elicit anti-inflammatory actions and to promote vascular endothelial function by activating type 1 and 3 melanocortin receptors. Here, we addressed whether these favorable properties of melanocort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3395f86bc6cb0757ff6ebf2f6d27923d
https://doi.org/10.1161/ATVBAHA.113.302963
https://doi.org/10.1161/ATVBAHA.113.302963
Autor:
Erik G. Larsson, Sofie Mellberg, Hua Huang, Martin Teichert, Patrik Georgii-Hemming, Irina Alafuzoff, Hellmut G. Augustin, Lei Zhang, Agata Zieba, Grietje Molema, Anna Dimberg, Elise Langenkamp, Henriikka Salomäki, Fredrik Pontén, Theo F. J. Kraus, Per Henrik Edqvist, Lothar C. Dieterich, Tommie Olofsson, Ola Söderberg
Publikováno v:
The Journal of Pathology. 228:378-390
Glioblastoma are aggressive astrocytic brain tumours characterized by microvascular proliferation and an abnormal vasculature, giving rise to brain oedema and increased patient morbidity. Here, we ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33fde730553af118dffa97c414ef07f0
https://doi.org/10.1002/path.4072
https://doi.org/10.1002/path.4072