Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Henriette, Pilegaard"'
Autor:
Weijia Feng, Gerard Arrey, Egija Zole, Wei lv, Xue Liang, Peng Han, Marghoob Mohiyuddin, Henriette Pilegaard, Birgitte Regenberg
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 3059-3067 (2022)
Extrachromosomal circular DNA (eccDNA) of chromosomal origin is common in eukaryotic cells. Amplification of oncogenes on large eccDNA (ecDNA) can drive biological processes such as tumorigenesis, and identification of eccDNA by sequencing after remo
Externí odkaz:
https://doaj.org/article/e3304d2b332c4de69e74a8ed18951a2b
Autor:
Natascha Masselkhi Christensen, Stine Ringholm, Bjørg Thiellesen Buch, Anders Gudiksen, Jens Frey Halling, Henriette Pilegaard
Publikováno v:
Experimental Gerontology, Vol 172, Iss , Pp 112046- (2023)
Aging has been suggested to be associated with changes in oxidative capacity, autophagy, and mitophagy in the liver, but a simultaneous evaluation of these key cellular processes is lacking. Moreover, skeletal muscle transcriptional coactivator perox
Externí odkaz:
https://doaj.org/article/b93741ca177e4f6c8f6262dc824f9397
Autor:
Peter Plomgaard, Jakob S. Hansen, Logan K. Townsend, Anders Gudiksen, Niels H. Secher, Jens O. Clemmesen, Rene K. Støving, Jens P. Goetze, David C. Wright, Henriette Pilegaard
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectiveGrowth differentiation factor (GDF)-15 is implicated in regulation of metabolism and circulating GDF15 increases in response to exercise. The source and regulation of the exercise-induced increase in GDF15 is, however not known.MethodPlasma
Externí odkaz:
https://doaj.org/article/ce58d911641d489ab432f2d4f5be64b9
Autor:
Camilla Hansen, Karina Olsen, Henriette Pilegaard, Jens Bangsbo, Lasse Gliemann, Ylva Hellsten
Publikováno v:
Physiological Reports, Vol 9, Iss 14, Pp n/a-n/a (2021)
Abstract The influence of glucose and palmitic acid (PA) on mitochondrial respiration and emission of hydrogen peroxide (H2O2) was determined in skeletal muscle‐derived microvascular endothelial cells. Measurements were assessed in intact and perme
Externí odkaz:
https://doaj.org/article/fbd5f85e3646434ea6970df1c6e35ff6
Autor:
Janne R. Hingst, Rasmus Kjøbsted, Jesper B. Birk, Nicolas O. Jørgensen, Magnus R. Larsen, Kohei Kido, Jeppe Kjærgaard Larsen, Sasha A.S. Kjeldsen, Joachim Fentz, Christian Frøsig, Stephanie Holm, Andreas M. Fritzen, Tine L. Dohlmann, Steen Larsen, Marc Foretz, Benoit Viollet, Peter Schjerling, Peter Overby, Jens F. Halling, Henriette Pilegaard, Ylva Hellsten, Jørgen F.P. Wojtaszewski
Publikováno v:
Molecular Metabolism, Vol 40, Iss , Pp 101028- (2020)
Objective: Evidence for AMP-activated protein kinase (AMPK)-mediated regulation of skeletal muscle metabolism during exercise is mainly based on transgenic mouse models with chronic (lifelong) disruption of AMPK function. Findings based on such model
Externí odkaz:
https://doaj.org/article/7b639b94cb3449f3af4191459a29d7c6
Autor:
Henrik Devitt Møller, Marghoob Mohiyuddin, Iñigo Prada-Luengo, M. Reza Sailani, Jens Frey Halling, Peter Plomgaard, Lasse Maretty, Anders Johannes Hansen, Michael P. Snyder, Henriette Pilegaard, Hugo Y. K. Lam, Birgitte Regenberg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Somatic cells can accumulate structural variations such as deletions. Here, Møller et al. show that normal human cells generate large extrachromosomal circular DNAs (eccDNAs), most likely the products of excised DNA, that can be transcriptionally ac
Externí odkaz:
https://doaj.org/article/05b697de38844d63ad7af833e2a47a93
Autor:
Morten L. Høgild, Anders Gudiksen, Henriette Pilegaard, Hans Stødkilde‐Jørgensen, Steen Bønløkke Pedersen, Niels Møller, Jens O. L. Jørgensen, Niels Jessen
Publikováno v:
Physiological Reports, Vol 7, Iss 21, Pp n/a-n/a (2019)
Abstract Fasting in human subjects shifts skeletal muscle metabolism toward lipid utilization and accumulation, including intramyocellular lipid (IMCL) deposition. Growth hormone (GH) secretion amplifies during fasting and promotes lipolysis and lipi
Externí odkaz:
https://doaj.org/article/4c1575a180374c6b92c04d1b9f556c7f
Autor:
Morten Hostrup, Jakob Grunnet Knudsen, Caroline Maag Kristensen, Søren Jessen, Henriette Pilegaard, Jens Bangsbo
Publikováno v:
Hostrup, M, Knudsen, J G, Maag Kristensen, C, Jessen, S, Pilegaard, H & Bangsbo, J 2022, ' Beta 2-agonist increases skeletal muscle interleukin 6 production and release in response to resistance exercise in men ', Scandinavian Journal of Medicine & Science in Sports, vol. 32, no. 7, pp. 1099-1108 . https://doi.org/10.1111/sms.14171
Objective: Several tissues produce and release interleukin-6 (IL-6) in response to beta2-adrenergic stimulation with selective agonists (beta2-agonists). Moreover, exercise stimulates muscle IL-6 production, but whether beta2-agonists regulate skelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e04dfc0a16dba711bd0cdd4366725524
https://doi.org/10.1111/sms.14171
https://doi.org/10.1111/sms.14171
Autor:
Rasmus Kjøbsted, Jonas M. Kristensen, Nicolas O. Eskesen, Kohei Kido, Klara Fjorder, Ditte F. Damgaard, Jeppe K. Larsen, Nicoline R. Andersen, Jesper B. Birk, Anders Gudiksen, Jonas T. Treebak, Peter Schjerling, Henriette Pilegaard, Jørgen F. P. Wojtaszewski
Publikováno v:
Kjøbsted, R, Kristensen, J M, Eskesen, N O, Kido, K, Fjorder, K, Damgaard, D F, Larsen, J K, Andersen, N R, Birk, J B, Gudiksen, A, Treebak, J T, Schjerling, P, Pilegaard, H & Wojtaszewski, J 2023, ' TBC1D4-S711 controls skeletal muscle insulin sensitization after exercise and contraction ', Diabetes, vol. 72, no. 7, pp. 857-871 . https://doi.org/10.2337/db22-0666
The ability of insulin to stimulate glucose uptake in skeletal muscle is important for whole-body glycemic control. Insulin-stimulated skeletal muscle glucose uptake is improved in the period after a single bout of exercise and accumulating evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a89498ca981548113ae9d2d065d9355c
https://curis.ku.dk/ws/files/344709125/Kjobsted_et_al_Diabetes_2023_TBC1D4_S711A_manuscript_Submitted_version_.pdf
https://curis.ku.dk/ws/files/344709125/Kjobsted_et_al_Diabetes_2023_TBC1D4_S711A_manuscript_Submitted_version_.pdf
Autor:
Anders Gudiksen, Albina Qoqaj, Stine Ringholm, Jørgen Wojtaszewski, Peter Plomgaard, Henriette Pilegaard
Publikováno v:
Gudiksen, A, Qoqaj, A, Ringholm, S, Wojtaszewski, J, Plomgaard, P & Pilegaard, H 2022, ' Ameliorating effects of lifelong physical activity on healthy aging and mitochondrial function in human white adipose tissue ', Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, vol. 77, no. 6, pp. 1101-1111 . https://doi.org/10.1093/gerona/glab356
Growing old is patently among the most prominent risk factors for lifestyle-related diseases and deterioration in physical performance. Aging in particular affects mitochondrial homeostasis, and maintaining a well-functioning mitochondrial pool is im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1385e8c44822b408a7309ff88310a4dc
https://doi.org/10.1093/gerona/glab356
https://doi.org/10.1093/gerona/glab356