Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Henriette, Macmillan"'
Autor:
Natasha Spottiswoode, Samantha Hao, Estella Sanchez-Guerrero, Angela M. Detweiler, Honey Mekonen, Norma Neff, Henriette Macmillan, Brian S. Schwartz, Joanne Engel, Joseph L. DeRisi, Steven A. Miller, Charles R. Langelier
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Multidrug-resistant (MDR) Pseudomonas aeruginosa has been declared a serious threat by the United States Centers for Disease Control and Prevention. Here, we used whole genome sequencing (WGS) to investigate recurrent P. aeruginosa bloodstream infect
Externí odkaz:
https://doaj.org/article/2828eeef9fac42af85ebf115d386a7b2
Two antagonistic response regulators control Pseudomonas aeruginosa polarization during mechanotaxis
Autor:
Marco J Kühn, Henriette Macmillan, Lorenzo Talà, Yuki Inclan, Ramiro Patino, Xavier Pierrat, Zainebe Al‐Mayyah, Joanne N Engel, Alexandre Persat
Publikováno v:
The EMBO Journal. 42
The opportunistic pathogen Pseudomonas aeruginosa adapts to solid surfaces to enhance virulence and infect its host. Type IV pili (T4P), long and thin filaments that power surface-specific twitching motility, allow single cells to sense surfaces and
Autor:
Marco J. Kühn, Henriette Macmillan, Lorenzo Talà, Yuki Inclan, Ramiro Patino, Xavier Pierrat, Zainebe Al-Mayyah, Joanne N. Engel, Alexandre Persat
The opportunistic pathogenPseudomonas aeruginosaadapts to solid surfaces to enhance virulence and infect its host. Type IV pili (T4P), long and thin filaments that power surface-specific twitching motility, allow single cells to mechanosense surfaces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2907b4b2e1319763a0288db2a2054a0a
https://doi.org/10.1101/2022.11.15.516588
https://doi.org/10.1101/2022.11.15.516588
Publikováno v:
F1000Research, Vol 4 (2016)
Autoantibodies against antigens expressed by insulin-producing β cells are circulating in both healthy individuals and patients at risk of developing Type 1 diabetes. Recent studies suggest that another set of antibodies (anti-idiotypic antibodies)
Externí odkaz:
https://doaj.org/article/435398f7b92049f49ec261eaa3b88107
Autor:
Marco J, Kühn, Lorenzo, Talà, Yuki F, Inclan, Ramiro, Patino, Xavier, Pierrat, Iscia, Vos, Zainebe, Al-Mayyah, Henriette, Macmillan, Jose, Negrete, Joanne N, Engel, Alexandre, Persat
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Single cells across kingdoms of life explore, prey, escape, or congregate using surface-specific motility. Motile eukaryotic cells use chemotaxis to direct migration on surfaces. However, how bacteria control surface motility remains und
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
B cell receptors and surface-displayed peptide/MHCII complexes constitute two key components of the B-cell machinery to sense signals and communicate with other cell types during antigen-triggered activation. However, critical pathways synergizing an
Publikováno v:
F1000Research
Autoantibodies against antigens expressed by insulin-producing β cells are circulating in both healthy individuals and patients at risk of developing Type 1 diabetes. Recent studies suggest that another set of antibodies (anti-idiotypic antibodies)
Autor:
Taejin Yoon, Catherine L. Keech, Michael J. Strohman, Elizabeth D. Mellins, Henriette Macmillan, John Sidney, Xi Jin, Zhenjun Chen, Tieying Hou
Publikováno v:
The Journal of Immunology. 187:2442-2452
HLA-DM (DM) catalyzes CLIP release, stabilizes MHC class II molecules, and edits the peptide repertoire presented by class II. Impaired DM function may have profound effects on Ag presentation events in the thymus and periphery that are critical for
Publikováno v:
The Journal of Immunology. 200:99.28-99.28
HLA-DO, a non-classical class II major histocompatibility complex (MHCII), competitively inhibits HLA-DM in B cells. B cells lower DO levels during antigen-mediated activation in germinal centers, implying a regulatory function of DO in resting B cel
Autor:
Timo Burster, Bernhard O. Boehm, Henriette Macmillan, Phi Truong, Tieying Hou, Elizabeth D. Mellins, Michael J. Strohman, Kenneth Lau, Robert Busch, James Schilling, Steven Schaffert, Fang Zou
Publikováno v:
Immunology. 130:436-446
SUMMARY The expression of major histocompatibility complex class II (MHC II) molecules is post-translationally regulated by endocytic protein turnover. Here, we identified the serine protease cathepsin G (CatG) as an MHC II-degrading protease by in v