Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Henri-Marc G Bourbon"'
Autor:
Denis Jullien, Emmanuelle Guillou, Sandra Bernat-Fabre, Adeline Payet, Henri-Marc G Bourbon, Muriel Boube
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0275613 (2022)
The multi-subunit Mediator complex plays a critical role in gene expression by bridging enhancer-bound transcription factors and the RNA polymerase II machinery. Although experimental case studies suggest differential roles of Mediator subunits, a co
Externí odkaz:
https://doaj.org/article/ee12978a4fd347a5b1720d033303d601
Autor:
Xiao Li, Mengmeng Liu, Xingjie Ren, Nicolas Loncle, Qun Wang, Rajitha-Udakara-Sampath Hemba-Waduge, Stephen H Yu, Muriel Boube, Henri-Marc G Bourbon, Jian-Quan Ni, Jun-Yuan Ji
Publikováno v:
PLoS Genetics, Vol 16, Iss 5, p e1008832 (2020)
Dysregulation of CDK8 (Cyclin-Dependent Kinase 8) and its regulatory partner CycC (Cyclin C), two subunits of the conserved Mediator (MED) complex, have been linked to diverse human diseases such as cancer. Thus, it is essential to understand the reg
Externí odkaz:
https://doaj.org/article/4e4346374603407a93e13c02794c0c5c
Autor:
Alexander Woglar, Kei Yamaya, Anne M. Villeneuve, Albert W. Hinman, Henri-Marc G Bourbon, Baptiste Roelens, Peter Chi, Hsin-Yi Yeh
Publikováno v:
Proc Natl Acad Sci U S A
Meiotic recombination plays dual roles in the evolution and stable inheritance of genomes: Recombination promotes genetic diversity by reassorting variants, and it establishes temporary connections between pairs of homologous chromosomes that ensure
Autor:
Henri-Marc G. Bourbon, Mikhail H. Benetah, Emmanuelle Guillou, Luis Humberto Mojica-Vazquez, Aissette Baanannou, Sandra Bernat-Fabre, Vincent Loubiere, Frédéric Bantignies, Giacomo Cavalli, Muriel Boube
Publikováno v:
PLOS Genetics. 18:e1010083
Gene duplications and transcriptional enhancer emergence/modifications are thought having greatly contributed to phenotypic innovations during animal evolution. Nevertheless, little is known about how enhancers evolve after gene duplication and how r