Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Henri-Baptiste Marjault"'
Autor:
Linda Rowland, Henri-Baptiste Marjault, Ola Karmi, DeAna Grant, Lauren J. Webb, Assaf Friedler, Rachel Nechushtai, Ron Elber, Ron Mittler
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Cell Penetrating Peptides (CPPs) are promising anticancer and antimicrobial drugs. We recently reported that a peptide derived from the human mitochondrial/ER membrane-anchored NEET protein, Nutrient Autophagy Factor 1 (NAF-1; NAF-144-67), s
Externí odkaz:
https://doaj.org/article/b4d3c35acc764f168760d30991e8cfdd
Autor:
Henri-Baptiste Marjault, Ola Karmi, Ke Zuo, Dorit Michaeli, Yael Eisenberg-Domovich, Giulia Rossetti, Benoit de Chassey, Jacky Vonderscher, Ioav Cabantchik, Paolo Carloni, Ron Mittler, Oded Livnah, Eric Meldrum, Rachel Nechushtai
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
Marjault et al. report two crystal structures of a drug molecule bound to NEET proteins mNT and NAF-1 and the effects of this molecule on diabetic mice, suggesting an approach for reducing mitochondrial iron and ROS levels in diabetic patients.
Externí odkaz:
https://doaj.org/article/5fdc9f8e63f74c36ac4f3fdb8fd0831a
Autor:
Ola Karmi, Yang-Sung Sohn, Henri-Baptiste Marjault, Tal Israeli, Gil Leibowitz, Konstantinos Ioannidis, Yaakov Nahmias, Ron Mittler, Ioav Z. Cabantchik, Rachel Nechushtai
Publikováno v:
Antioxidants, Vol 10, Iss 8, p 1160 (2021)
Decreased insulin secretion, associated with pancreatic β-cell failure, plays a critical role in many human diseases including diabetes, obesity, and cancer. While numerous studies linked β-cell failure with enhanced levels of reactive oxygen speci
Externí odkaz:
https://doaj.org/article/445d18587fbe4b629ebd01f35f244779
Autor:
Yang Sung Sohn, Anat losub-Amir, Alfredo E. Cardenas, Ola Karmi, Merav Darash Yahana, Tal Gruman, Linda Rowland, Henri-Baptiste Marjault, Lauren J. Webb, Ron Mittler, Ron Elber, Assaf Friedler, Rachel Nechushtai
Publikováno v:
Chemical science. 13(23)
An effective anti-cancer therapy should exclusively target cancer cells and trigger in them a broad spectrum of cell death pathways that will prevent avoidance. Here, we present a new approach in cancer therapy that specifically targets the mitochond
Autor:
Henri-Baptiste Marjault, Guo-Feng Luo, Yonatan Biniuri, Jianbang Wang, Martin Winkler, Ehud Neumann, Thomas Happe, Itamar Willner, Wei-Hai Chen, Rachel Nechushtai
Publikováno v:
Angewandte Chemie. 132:9248-9255
All-DNA scaffolds act as templates for the organization of photosystem I model systems. A series of DNA templates composed of ZnII -protoporphyrin IX (ZnII PPIX)-functionalized G-quadruplex conjugated to the 3'- or 5'-end of the tyrosinamide (TA) apt
Autor:
Ola Karmi, Henri-Baptiste Marjault, Fang Bai, Susmita Roy, Yang-Sung Sohn, Merav Darash Yahana, Faruck Morcos, Konstantinos Ioannidis, Yaakov Nahmias, Patricia A. Jennings, Ron Mittler, José N. Onuchic, Rachel Nechushtai
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(7)
Mitochondrial inner NEET (MiNT) and the outer mitochondrial membrane (OMM) mitoNEET (mNT) proteins belong to the NEET protein family. This family plays a key role in mitochondrial labile iron and reactive oxygen species (ROS) homeostasis. NEET protei
Autor:
Henri-Baptiste Marjault, David Stone, Guo-Feng Luo, Wei-Hai Chen, Itamar Willner, Ehud Neumann, Zhixin Zhou, Rachel Nechushtai
Publikováno v:
Nano Letters. 19:9121-9130
The broadband C3N4 semiconductor absorbs in the UV region, λ = 330-380 nm, a feature limiting its application for light-to-energy conversion. The unique surface adsorption properties of C3N4 allow, however, the binding of a photosensitizer, operatin
Autor:
Yaakov Nahmias, Ola Karmi, Ron Mittler, Henri-Baptiste Marjault, Yang Sung Sohn, Gil Leibowitz, Konstantinos Ioannidis, Tal Israeli, Rachel Nechushtai, Ioav Cabantchik
Publikováno v:
Antioxidants
Volume 10
Issue 8
Antioxidants, Vol 10, Iss 1160, p 1160 (2021)
Volume 10
Issue 8
Antioxidants, Vol 10, Iss 1160, p 1160 (2021)
Decreased insulin secretion, associated with pancreatic β-cell failure, plays a critical role in many human diseases including diabetes, obesity, and cancer. While numerous studies linked β-cell failure with enhanced levels of reactive oxygen speci
Autor:
Henri-Baptiste Marjault, Rachel Nechushtai, Guo-Feng Luo, Yonatan Biniuri, Anjan Bedi, Wei-Hai Chen, Ehud Neumann, Itamar Willner, Thomas Happe, David Stone, Ori Gidron, Michael Fadeev
Publikováno v:
Nano Letters. 19:6621-6628
Sequence-specific aptamers act as functional scaffolds for the assembly of photosynthetic model systems. The Ru(II)-tris-bipyridine photosensitizer is conjugated by different binding modes to the antityrosinamide aptamer to yield a set of photosensit
Autor:
Fang Bai, Ola Karmi, Guy Mayer, Yang Sung Sohn, Henri-Baptiste Marjault, José N. Onuchic, Sagi Tamir, Patricia A. Jennings, Assaf Friedler, Rachel Nechushtai, Ron Mittler, Luhua Song, Anat Iosub-Amir
Publikováno v:
Chemical Science
We reveal a novel interaction between the two anti-apoptotic proteins iASPP and NAF-1, which are overexpressed in many types of cancer cells, and propose that this interaction is required for apoptosis activation in cancer cells. A peptide derived fr