Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Henri-Alexandre Michaud"'
Autor:
Yaël Glasson, Laure-Agnès Chépeaux, Anne-Sophie Dumé, Philippe Jay, Nelly Pirot, Nathalie Bonnefoy, Henri-Alexandre Michaud
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Currently, the study of resistance mechanisms and disease progression in cancer relies on the capacity to analyze tumors as a complex ecosystem of healthy and malignant cells. Therefore, one of the current challenges is to decipher the intra-tumor he
Externí odkaz:
https://doaj.org/article/49ff55de47584104aef0b8187ecdf13a
Autor:
Yahya Ashraf, Hanane Mansouri, Valérie Laurent-Matha, Lindsay B. Alcaraz, Pascal Roger, Séverine Guiu, Danielle Derocq, Gautier Robin, Henri-Alexandre Michaud, Helène Delpech, Marta Jarlier, Martine Pugnière, Bruno Robert, Anthony Puel, Lucie Martin, Flavie Landomiel, Thomas Bourquard, Oussama Achour, Ingrid Fruitier-Arnaudin, Alexandre Pichard, Emmanuel Deshayes, Andrei Turtoi, Anne Poupon, Joëlle Simony-Lafontaine, Florence Boissière-Michot, Nelly Pirot, Florence Bernex, William Jacot, Stanislas du Manoir, Charles Theillet, Jean-Pierre Pouget, Isabelle Navarro-Teulon, Nathalie Bonnefoy, André Pèlegrin, Thierry Chardès, Pierre Martineau, Emmanuelle Liaudet-Coopman
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-17 (2019)
Abstract Background Triple-negative breast cancer (TNBC) treatment is currently restricted to chemotherapy. Hence, tumor-specific molecular targets and/or alternative therapeutic strategies for TNBC are urgently needed. Immunotherapy is emerging as a
Externí odkaz:
https://doaj.org/article/29cfb2cf1cb546cb9c2f21a1f397c343
Autor:
Ivan Perrot, Henri-Alexandre Michaud, Marc Giraudon-Paoli, Séverine Augier, Aurélie Docquier, Laurent Gros, Rachel Courtois, Cécile Déjou, Diana Jecko, Ondine Becquart, Hélène Rispaud-Blanc, Laurent Gauthier, Benjamin Rossi, Stéphanie Chanteux, Nicolas Gourdin, Beatrice Amigues, Alain Roussel, Armand Bensussan, Jean-François Eliaou, Jérémy Bastid, François Romagné, Yannis Morel, Emilie Narni-Mancinelli, Eric Vivier, Carine Paturel, Nathalie Bonnefoy
Publikováno v:
Cell Reports, Vol 27, Iss 8, Pp 2411-2425.e9 (2019)
Summary: Immune checkpoint inhibitors have revolutionized cancer treatment. However, many cancers are resistant to ICIs, and the targeting of additional inhibitory signals is crucial for limiting tumor evasion. The production of adenosine via the seq
Externí odkaz:
https://doaj.org/article/5587ee70bc8c4270948f7103cc944bcd
Autor:
Clément Barjon, Henri-Alexandre Michaud, Angeline Fages, Cécile Dejou, Alexandre Zampieri, Laetitia They, Aurélie Gennetier, Françoise Sanchez, Laurent Gros, Jean-François Eliaou, Nathalie Bonnefoy, Virginie Lafont
Publikováno v:
OncoImmunology, Vol 7, Iss 1 (2018)
Vγ9Vδ2 T cells contribute to the immune response against many tumor types through their direct cytotoxic activity and capacity to regulate the biological functions of other immune cells, such as dendritic cells and IFN-γ-producing CD8+ T cells. Ho
Externí odkaz:
https://doaj.org/article/558638ed3e754130a8d2e0ec44e88c32
Autor:
Laetitia They, Henri-Alexandre Michaud, Ondine Becquart, Virginie Lafont, Bernard Guillot, Florence Boissière-Michot, Marta Jarlier, Caroline Mollevi, Jean-François Eliaou, Nathalie Bonnefoy, Laurent Gros
Publikováno v:
OncoImmunology, Vol 6, Iss 10 (2017)
Tumor antigen-targeting monoclonal antibodies (TA-targeting mAbs) are used as therapeutics in many malignancies and their capacity to mobilize the host immunity puts them at the forefront of anti-cancer immunotherapies. Both innate and adaptive immun
Externí odkaz:
https://doaj.org/article/b0b6a65285064616819acd3a9f1129c4
Autor:
Henri-Alexandre Michaud, Tiphanie Gomard, Laurent Gros, Kevin Thiolon, Roudaina Nasser, Chantal Jacquet, Javier Hernandez, Marc Piechaczyk, Mireia Pelegrin
Publikováno v:
PLoS Pathogens, Vol 6, Iss 6, p e1000948 (2010)
Antiviral monoclonal antibodies (mAbs) represent promising therapeutics. However, most mAbs-based immunotherapies conducted so far have only considered the blunting of viral propagation and not other possible therapeutic effects independent of virus
Externí odkaz:
https://doaj.org/article/81054ed7d4bc41e5898a6c797b3603e3
Autor:
Tiphanie Gomard, Henri-Alexandre Michaud, Denis Tempé, Kevin Thiolon, Mireia Pelegrin, Marc Piechaczyk
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9585 (2010)
BACKGROUND: Dendritic cells (DCs) play a key role in the induction of adaptive and memory immune responses. Upon encounter with pathogens, they undergo a complex maturation process and migrate toward lymphoid organs where they stimulate immune effect
Externí odkaz:
https://doaj.org/article/5e2eb5ed204840aeb9341ccebf3d1619
Autor:
Lamine Alaoui, Javiera Villar, Renaud Leclere, Simon Le Gallou, Francis Relouzat, Henri-Alexandre Michaud, Karin Tarte, Natacha Teissier, Benoît Favier, Mikaël Roussel, Elodie Segura
Publikováno v:
Journal of Experimental Medicine
Journal of Experimental Medicine, 2023, 220 (7), pp.e20230002. ⟨10.1084/jem.20230002⟩
Journal of Experimental Medicine, 2023, 220 (7), pp.e20230002. ⟨10.1084/jem.20230002⟩
International audience; Macrophages play a central role in tissue homeostasis and host defense. However, the properties of human macrophages in non-diseased tissues remain poorly understood. Here, we characterized human tonsil macrophages and identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443a94292a6e3533defbd80f42ce9af2
https://hal.science/hal-04090249
https://hal.science/hal-04090249
Autor:
Celine Gongora, Nadia Vezzio-Vie, Roderick L. Beijersbergen, Maguy Del Rio, Pierre Martineau, Jerome Moreaux, Nathalie Bonnefoy, Philippe Pasero, Arnaud Coquelle, Marta Jarlier, Delphine Desigaud, Veronique Garambois, Flavie Coquel, Henri-Alexandre Michaud, Diego Tosi, Augusto F. Andrade, Eve Combès
Oxaliplatin combined with the ATR inhibitor VE-822 induces immune death signalling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1967a627961a165c7e604fc22df7e2d
https://doi.org/10.1158/0008-5472.22420949
https://doi.org/10.1158/0008-5472.22420949
Autor:
Celine Gongora, Nadia Vezzio-Vie, Roderick L. Beijersbergen, Maguy Del Rio, Pierre Martineau, Jerome Moreaux, Nathalie Bonnefoy, Philippe Pasero, Arnaud Coquelle, Marta Jarlier, Delphine Desigaud, Veronique Garambois, Flavie Coquel, Henri-Alexandre Michaud, Diego Tosi, Augusto F. Andrade, Eve Combès
Although many patients with colorectal cancer initially respond to the chemotherapeutic agent oxaliplatin, acquired resistance to this treatment remains a major challenge to the long-term management of this disease. To identify molecular targets of o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc9ed29041f254d948ae7a38444cd60
https://doi.org/10.1158/0008-5472.c.6510791.v1
https://doi.org/10.1158/0008-5472.c.6510791.v1