Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Henri Voedts"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
β-lactam-induced bacterial killing is complex and not fully resolved. Authors carry out a genome-wide analysis, through penicillin-binding protein replacement, to identify genes essential for drug efficacy.
Externí odkaz:
https://doaj.org/article/cb6efd426f0747438396c3f0af0e152d
Autor:
Nathanael A. Caveney, Guillermo Caballero, Henri Voedts, Ana Niciforovic, Liam J. Worrall, Marija Vuckovic, Matthieu Fonvielle, Jean-Emmanuel Hugonnet, Michel Arthur, Natalie C. J. Strynadka
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
In E. coli, alternate peptidoglycan crosslinking reactions carried out by the L,D-transpeptidase YcbB can lead to beta-lactam resistance. Here, Caveney et al. solve the crystal structure of YcbB and shed light into its mechanism of action and into Yc
Externí odkaz:
https://doaj.org/article/5893b624e29f4e1b9969ad99f17cd15a
Autor:
Waldemar Vollmer, Henri Voedts, Adam Lodge, Jean-Emmanuel Hugonnet, Delphine Dorchêne, Michel Arthur
Publikováno v:
EMBO J
EMBO Journal
EMBO Journal, EMBO Press, 2021, 40 (19), ⟨10.15252/embj.2021108126⟩
EMBO Journal
EMBO Journal, EMBO Press, 2021, 40 (19), ⟨10.15252/embj.2021108126⟩
Bacteria resist to the turgor pressure of the cytoplasm through a net-like macromolecule, the peptidoglycan, made of glycan strands connected via peptides cross-linked by penicillin-binding proteins (PBPs). We recently reported the emergence of β-la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f3ca90e046e0e9a8bedc98e139959b
https://europepmc.org/articles/PMC8488565/
https://europepmc.org/articles/PMC8488565/
Autor:
Michel Arthur, G. Caballero, Natalie C. J. Strynadka, Nathanael A. Caveney, Ana P. Niciforovic, Liam J. Worrall, Jean-Emmanuel Hugonnet, Matthieu Fonvielle, Marija Vuckovic, Henri Voedts
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
The bacterial cell wall plays a crucial role in viability and is an important drug target. In Escherichia coli, the peptidoglycan crosslinking reaction to form the cell wall is primarily carried out by penicillin-binding proteins that catalyse D,D-tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::375fbbcd034cb83e64d154162fa96617
https://doaj.org/article/5893b624e29f4e1b9969ad99f17cd15a
https://doaj.org/article/5893b624e29f4e1b9969ad99f17cd15a